The role of Cullin3-mediated ubiquitination of the catalytic subunit of PP2A in TRAIL signaling

Combining TRAIL with PI3 kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling

(2015) Grazia Saturno et al.   Oncotarget

Regulation of the Src-PP2A Interaction in Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis

(2013) Jing Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors

(2012) Hairong Cheng et al.   CELL CYCLE

Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells

(2011) Juan Wang et al.   CELL CYCLE

Activation of the Akt Survival Pathway Contributes to TRAIL Resistance in Cancer Cells

(2010) Jing Xu et al.   PLoS One

TRAIL as a target in anti-cancer therapy

(2009) Gen Sheng Wu   CANCER LETTERS

Serine/Threonine Phosphatases: Mechanism through Structure

(2009) Yigong Shi   CELL

Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling

(2009) Zhaoyu Jin et al.   CELL

Mapatumumab, a Fully Human Agonistic Monoclonal Antibody That Targets TRAIL-R1, in Combination with Gemcitabine and Cisplatin: a Phase I Study

(2009) C. H. Mom et al.   CLINICAL CANCER RESEARCH

Mapatumumab, an Antibody Targeting TRAIL-R1, in Combination With Paclitaxel and Carboplatin in Patients With Advanced Solid Malignancies: Results of a Phase I and Pharmacokinetic Study

(2009) Stephen Leong et al.   JOURNAL OF CLINICAL ONCOLOGY

α4 Is an Essential Regulator of PP2A Phosphatase Activity

(2009) Mei Kong et al.   MOLECULAR CELL

Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms

(2009) Jie Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype

(2008) Monzur Rahman et al.   BREAST CANCER RESEARCH AND TREATMENT

Identification of PP2A as a crucial regulator of the NF-κB feedback loop: its inhibition by UVB turns NF-κB into a pro-apoptotic factor

(2008) S Barisic et al.   CELL DEATH AND DIFFERENTIATION

Cullin-RING ubiquitin ligases: global regulation and activation cycles

(2008) Dimple R Bosu et al.   Cell Division