Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau
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Title
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau
Authors
Keywords
Tau, Neuronal injury, Late-stage, Anle138b, Small animal PET
Journal
Alzheimers Research & Therapy
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-08-01
DOI
10.1186/s13195-019-0522-z
References
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Note: Only part of the references are listed.- Molecular imaging in dementia: Past, present, and future
- (2018) R. Laforce et al. Alzheimers & Dementia
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- (2018) Tharick A. Pascoal et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
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- (2017) The Lancet Neurology LANCET NEUROLOGY
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- (2016) T A Pascoal et al. MOLECULAR PSYCHIATRY
- A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers
- (2016) Clifford R. Jack et al. NEUROLOGY
- Bapineuzumab for mild to moderate Alzheimer’s disease in two global, randomized, phase 3 trials
- (2016) Rik Vandenberghe et al. Alzheimers Research & Therapy
- Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies
- (2015) Jens Wagner et al. ACTA NEUROPATHOLOGICA
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- (2015) M Brendel et al. MOLECULAR PSYCHIATRY
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- (2014) Johannes Levin et al. ACTA NEUROPATHOLOGICA
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- Intravenous immunoglobulin for treatment of mild-to-moderate Alzheimer's disease: a phase 2, randomised, double-blind, placebo-controlled, dose-finding trial
- (2013) Richard Dodel et al. LANCET NEUROLOGY
- Cognitive reserve associated with FDG-PET in preclinical Alzheimer disease
- (2013) M. Ewers et al. NEUROLOGY
- Are Tau Aggregates Toxic or Protective in Tauopathies?
- (2013) Catherine M. Cowan et al. Frontiers in Neurology
- The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Guy M. McKhann et al. Alzheimers & Dementia
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- (2010) A. Rominger et al. JOURNAL OF NUCLEAR MEDICINE
- Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
- (2010) Carol Kilkenny et al. PLOS BIOLOGY
- Classification and basic pathology of Alzheimer disease
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