Amyloid-β and hyperphosphorylated tau synergy drives metabolic decline in preclinical Alzheimer’s disease

Cerebrospinal fluid tau and amyloid-β1-42in patients with dementia

(2015) Tobias Skillbäck et al.   BRAIN

Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

(2015) Sylvia Villeneuve et al.   BRAIN

The mediational effects of FDG hypometabolism on the association between cerebrospinal fluid biomarkers and neurocognitive function

(2015) N. Maritza Dowling et al.   NEUROIMAGE

Cerebrospinal fluid β-amyloid and phospho-tau biomarker interactions affecting brain structure in preclinical Alzheimer disease

(2014) Juan Fortea et al.   ANNALS OF NEUROLOGY

Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease

(2014) Niklas Mattsson et al.   BRAIN

Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons

(2014) Rodrigo A. Quintanilla et al.   NEUROBIOLOGY OF DISEASE

Synergistic effects of amyloid-beta and wild-type human tau on dendritic spine loss in a floxed double transgenic model of Alzheimer's disease

(2014) Meredith A. Chabrier et al.   NEUROBIOLOGY OF DISEASE

Rates of  -amyloid accumulation are independent of hippocampal neurodegeneration

(2014) C. R. Jack et al.   NEUROLOGY

Association of hypometabolism and amyloid levels in aging, normal subjects

(2014) V. J. Lowe et al.   NEUROLOGY

The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials

(2014) Reisa Sperling et al.   NEURON

TDP-43 interaction with the intracellular domain of amyloid precursor protein induces p53-associated apoptosis

(2014) Jing Wang et al.   NEUROSCIENCE LETTERS

Synergistic Effect of β-Amyloid and Neurodegeneration on Cognitive Decline in Clinically Normal Individuals

(2014) Elizabeth C. Mormino et al.   JAMA Neurology

Brain amyloid-β oligomers in ageing and Alzheimer’s disease

(2013) Sylvain E. Lesné et al.   BRAIN

Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study

(2013) Stephanie JB Vos et al.   LANCET NEUROLOGY

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer's disease

(2013) Usman A Khan et al.   NATURE NEUROSCIENCE

Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later

(2013) C. M. Roe et al.   NEUROLOGY

Selective Worsening of Brain Injury Biomarker Abnormalities in Cognitively Normal Elderly Persons With β-Amyloidosis

(2013) David S. Knopman et al.   JAMA Neurology

Amyloid-β–Associated Clinical Decline Occurs Only in the Presence of Elevated P-tau

(2012) Rahul S. Desikan et al.   ARCHIVES OF NEUROLOGY

Longitudinal imaging of Alzheimer pathology using [11C]PIB, [18F]FDDNP and [18F]FDG PET

(2012) Rik Ossenkoppele et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Apolipoprotein E, Not Fibrillar  -Amyloid, Reduces Cerebral Glucose Metabolism in Normal Aging

(2012) W. J. Jagust et al.   JOURNAL OF NEUROSCIENCE

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease

(2012) D. S. Knopman et al.   NEUROLOGY

Tau pathology in children and young adults: can you still be unconditionally baptist?

(2011) Charles Duyckaerts   ACTA NEUROPATHOLOGICA

Amyloid-β associated volume loss occurs only in the presence of phospho-tau

(2011) Rahul S. Desikan et al.   ANNALS OF NEUROLOGY

BEaST: Brain extraction based on nonlocal segmentation technique

(2011) Simon F. Eskildsen et al.   NEUROIMAGE

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

(2010) Kaj Blennow et al.   Nature Reviews Neurology

Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

(2010) Lars M. Ittner et al.   NATURE REVIEWS NEUROSCIENCE

Total and phosphorylated tau protein as biological markers of Alzheimer’s disease

(2009) Harald Hampel et al.   EXPERIMENTAL GERONTOLOGY

Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

(2008) Milos D. Ikonomovic et al.   BRAIN

Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease

(2008) L. Mosconi et al.   NEUROLOGY

Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis

(2008) Scott A. Small et al.   NEURON