Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies
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Title
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies
Authors
Keywords
Alzheimer’s disease, Tauopathy, Tau, Protein aggregation, Anle138b, Tau aggregation inhibitor
Journal
ACTA NEUROPATHOLOGICA
Volume 130, Issue 5, Pages 619-631
Publisher
Springer Nature
Online
2015-10-06
DOI
10.1007/s00401-015-1483-3
References
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- (2013) Maria Grazia Spillantini et al. LANCET NEUROLOGY
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- (2013) Kiran Yanamandra et al. NEURON
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- (2012) Erin E. Congdon et al. Autophagy
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- (2009) M. Polydoro et al. JOURNAL OF NEUROSCIENCE
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- (2009) Murat Oz et al. MEDICINAL RESEARCH REVIEWS
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