Cancer‐Specific Therapy by Artificial Modulation of Intracellular Calcium Concentration

Mitoxantrone-preloaded water-responsive phospholipid-amorphous calcium carbonate hybrid nanoparticles for targeted and effective cancer therapy

(2019) Cheng Wang et al.   International Journal of Nanomedicine

Enhanced Intracellular Ca2+ Nanogenerator for Tumor-Specific Synergistic Therapy via Disruption of Mitochondrial Ca2+ Homeostasis and Photothermal Therapy

(2018) Lihua Xu et al.   ACS Nano

Lipase-Triggered Water-Responsive “Pandora's Box” for Cancer Therapy: Toward Induced Neighboring Effect and Enhanced Drug Penetration

(2018) Cheng Wang et al.   ADVANCED MATERIALS

Encapsulation of cisplatin in a pegylated calcium phosphate nanoparticle (CPNP) for enhanced cytotoxicity to cancerous cells

(2017) Yang Ding et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability

(2017) Timothy S. Luongo et al.   NATURE

Taking advantage of the disadvantage: employing the high aqueous instability of amorphous calcium carbonate to realize burst drug release within cancer cells

(2017) Cheng Wang et al.   Journal of Materials Chemistry B

Targeting calcium signaling in cancer therapy

(2017) Chaochu Cui et al.   Acta Pharmaceutica Sinica B

In Situ Strategy to Encapsulate Antibiotics in a Bioinspired CaCO3 Structure Enabling pH-Sensitive Drug Release Apt for Therapeutic and Imaging Applications

(2016) Gousia Begum et al.   ACS Applied Materials & Interfaces

SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway

(2016) Zhao Jing et al.   CANCER LETTERS

Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca2+ ATPase activity in ovarian cancer cells

(2016) Jeong-ah Seo et al.   CANCER LETTERS

Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid

(2016) Stella Pesakhov et al.   Oncotarget

Self-Monitoring and Self-Delivery of Photosensitizer-Doped Nanoparticles for Highly Effective Combination Cancer Therapy in Vitro and in Vivo

(2015) Jinfeng Zhang et al.   ACS Nano

(−)-Englerin A is a Potent and Selective Activator of TRPC4 and TRPC5 Calcium Channels

(2015) Yasemin Akbulut et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Altered calcium signaling in cancer cells

(2015) Teneale A. Stewart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A Preloaded Amorphous Calcium Carbonate/Doxorubicin@Silica Nanoreactor for pH-Responsive Delivery of an Anticancer Drug

(2014) Yang Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amplified lipid rafts of malignant cells constitute a target for inhibition of aberrantly active NFAT and melanoma tumor growth by the aminobisphosphonate zoledronic acid

(2014) U. Levin-Gromiko et al.   CARCINOGENESIS

Preparation and Size Control of Sub-100 nm Pure Nanodrugs

(2014) Jinfeng Zhang et al.   NANO LETTERS

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia

(2014) Kunfu Ouyang et al.   Nature Communications

Simultaneous mitochondrial Ca2+ overload and proteasomal inhibition are responsible for the induction of paraptosis in malignant breast cancer cells

(2012) Mi Jin Yoon et al.   CANCER LETTERS

Orai3 is an estrogen receptor α-regulated Ca2+ channel that promotes tumorigenesis

(2012) Rajender K. Motiani et al.   FASEB JOURNAL

Mitochondria as sensors and regulators of calcium signalling

(2012) Rosario Rizzuto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy

(2012) S. R. Denmeade et al.   Science Translational Medicine

Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis

(2011) Y.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca2+ concentration

(2010) Mu Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Microbial excavation of solid carbonates powered by P-type ATPase-mediated transcellular Ca2+ transport

(2010) F. Garcia-Pichel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca2+ homeostasis

(2009) Jinhua Shen et al.   NATURE CELL BIOLOGY

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

(2008) Ajaikumar B. Kunnumakkara et al.   CANCER LETTERS

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY