Varroa destructor parasitism has a greater effect on proteome changes than the deformed wing virus and activates TGF-β signaling pathways

Quantitative proteomics reveals divergent responses in Apis mellifera worker and drone pupae to parasitization by Varroa destructor

(2018) Carla Surlis et al.   JOURNAL OF INSECT PHYSIOLOGY

Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila

(2018) Shrivani Sriskanthadevan-Pirahas et al.   PLoS Genetics

Proteome Comparisons between Hemolymph of Two Honeybee Strains (Apis mellifera ligustica) Reveal Divergent Molecular Basis in Driving Hemolymph Function and High Royal Jelly Secretion

(2017) Zewdu Ararso et al.   JOURNAL OF PROTEOME RESEARCH

Beyond the survival and death of the deltamethrin-threatened pollen beetle Meligethes aeneus : An in-depth proteomic study employing a transcriptome database

(2017) Tomas Erban et al.   Journal of Proteomics

Hippo signaling promotes JNK-dependent cell migration

(2017) Xianjue Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus and dsRNA-triggered transcriptional responses reveal key components of honey bee antiviral defense

(2017) Laura M. Brutscher et al.   Scientific Reports

Detailed proteome mapping of newly emerged honeybee worker hemolymph and comparison with the red-eye pupal stage

(2016) Tomas Erban et al.   APIDOLOGIE

Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila

(2016) Bo Liu et al.   CELL

Targeting the molecular mechanisms of ischemic damage: Protective effects of alpha-crystallin-B

(2016) Judit Cubedo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Royal Jelly: An ancient remedy with remarkable antibacterial properties

(2016) Filippo Fratini et al.   MICROBIOLOGICAL RESEARCH

CDD/SPARCLE: functional classification of proteins via subfamily domain architectures

(2016) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability

(2016) W-T Liu et al.   ONCOGENE

A mutualistic symbiosis between a parasitic mite and a pathogenic virus undermines honey bee immunity and health

(2016) Gennaro Di Prisco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated virulence of an emerging viral genotype as a driver of honeybee loss

(2016) Dino P. McMahon et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Deformed wing virus is a recent global epidemic in honeybees driven by Varroa mites

(2016) L. Wilfert et al.   SCIENCE

Tick–Host–Pathogen Interactions: Conflict and Cooperation

(2016) José de la Fuente et al.   PLoS Pathogens

Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals

(2016) Vicki P. Losick et al.   PLoS One

PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells

(2015) Bilal Rah et al.   Autophagy

CD109 attenuates TGF-β1 signaling and enhances EGF signaling in SK-MG-1 human glioblastoma cells

(2015) Jing-Min Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Draper/CED-1 Mediates an Ancient Damage Response to Control Inflammatory Blood Cell Migration In Vivo

(2015) Iwan Robert Evans et al.   CURRENT BIOLOGY

Rac1 augments Wnt signaling by stimulating  -catenin-lymphoid enhancer factor-1 complex assembly independent of  -catenin nuclear import

(2015) C. Jamieson et al.   JOURNAL OF CELL SCIENCE

Ras-activated Dsor1 promotes Wnt signaling in Drosophila development

(2015) E. T. Hall et al.   JOURNAL OF CELL SCIENCE

Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling

(2015) Andrew Archibald et al.   MOLECULAR BIOLOGY OF THE CELL

HSP70 binding protein 1 (HspBP1) suppresses HIV-1 replication by inhibiting NF-κB mediated activation of viral gene expression

(2015) Priyanka Chaudhary et al.   NUCLEIC ACIDS RESEARCH

Metabolic Methanol: Molecular Pathways and Physiological Roles

(2015) Yuri L. Dorokhov et al.   PHYSIOLOGICAL REVIEWS

In-depth proteomic analysis of Varroa destructor: Detection of DWV-complex, ABPV, VdMLV and honeybee proteins in the mite

(2015) Tomas Erban et al.   Scientific Reports

Antiviral defense mechanisms in honey bees

(2015) Laura M Brutscher et al.   Current Opinion in Insect Science

Perlecan Diversely Regulates the Migration and Proliferation of Distinct Cell Types in vitro

(2015) Ryosuke Nakamura et al.   CELLS TISSUES ORGANS

Overexpression of atypical protein kinase C in HeLa cells facilitates macropinocytosis via Src activation

(2014) Ellen J. Tisdale et al.   CELLULAR SIGNALLING

Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition

(2014) Rik Derynck et al.   CURRENT OPINION IN CELL BIOLOGY

Rab proteins: The key regulators of intracellular vesicle transport

(2014) Tanmay Bhuin et al.   EXPERIMENTAL CELL RESEARCH

Immunogene and viral transcript dynamics during parasitic Varroa destructor mite infection of developing honey bee (Apis mellifera) pupae

(2014) R. D. Kuster et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ

(2014) Jürgen Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

Innate Antiviral Host Defense Attenuates TGF-β Function through IRF3-Mediated Suppression of Smad Signaling

(2014) Pinglong Xu et al.   MOLECULAR CELL

Sorbitol dehydrogenase inhibitor protects the liver from ischemia/reperfusion-induced injury via elevated glycolytic flux and enhanced sirtuin 1 activity

(2014) CHANGHE ZHANG et al.   Molecular Medicine Reports

Influenza viral neuraminidase primes bacterial coinfection through TGF-β–mediated expression of host cell receptors

(2014) Ning Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ancient defense system eliminates unfit cells from developing tissues during cell competition

(2014) S. N. Meyer et al.   SCIENCE

A Virulent Strain of Deformed Wing Virus (DWV) of Honeybees (Apis mellifera) Prevails after Varroa destructor-Mediated, or In Vitro, Transmission

(2014) Eugene V. Ryabov et al.   PLoS Pathogens

Israeli Acute Paralysis Virus: Epidemiology, Pathogenesis and Implications for Honey Bee Health

(2014) Yan Ping Chen et al.   PLoS Pathogens

Regulation of the NF-κB-Mediated Transcription of Inflammatory Genes

(2014) Dev Bhatt et al.   Frontiers in Immunology

Are Reactive Oxygen Species Always Detrimental to Pathogens?

(2013) Claudia N. Paiva et al.   ANTIOXIDANTS & REDOX SIGNALING

Two-dimensional gel proteome analysis of honeybee, Apis mellifera, worker red-eye pupa hemolymph

(2013) Tomas Erban et al.   APIDOLOGIE

Src kinases mediate the interaction of the apical determinant Bazooka/PAR3 with STAT92E and increase signalling efficiency in Drosophila ectodermal cells

(2013) S. Sotillos et al.   DEVELOPMENT

The role of Ran-binding protein 3 during influenza A virus replication

(2013) R. Predicala et al.   JOURNAL OF GENERAL VIROLOGY

Regulation of Hepatitis B Virus Infection by Rab5, Rab7, and the Endolysosomal Compartment

(2013) A. Macovei et al.   JOURNAL OF VIROLOGY

The One Hour Yeast Proteome

(2013) Alexander S. Hebert et al.   MOLECULAR & CELLULAR PROTEOMICS

A Cdc42- and Rac-interactive binding (CRIB) domain mediates functions of coronin

(2013) K. Swaminathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tick salivary compounds: their role in modulation of host defences and pathogen transmission

(2013) Mária Kazimírová et al.   Frontiers in Cellular and Infection Microbiology

Nup358 interacts with Dishevelled and aPKC to regulate neuronal polarity

(2013) P. Vyas et al.   Biology Open

A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms

(2012) Nathan H. Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

1D and 2D annotation enrichment: a statistical method integrating quantitative proteomics with complementary high-throughput data

(2012) Juergen Cox et al.   BMC BIOINFORMATICS

Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis

(2012) A. B. Rodrigues et al.   DEVELOPMENT

The Drosophila BCL6 homolog ken and barbie promotes somatic stem cell self-renewal in the testis niche

(2012) Melanie Issigonis et al.   DEVELOPMENTAL BIOLOGY

Snf1-related kinase inhibits colon cancer cell proliferation through calcyclin-binding protein-dependent reduction of β-catenin

(2012) Amy K. Rines et al.   FASEB JOURNAL

Virus-induced changes in mitochondrial bioenergetics as potential targets for therapy

(2012) Tatiana El-Bacha et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The c-Jun N-terminal Kinase (JNK)-binding Protein (JNKBP1) Acts as a Negative Regulator of NOD2 Protein Signaling by Inhibiting Its Oligomerization Process

(2012) Aurore Lecat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Partitioning-defective Protein 6 (Par-6) Activates Atypical Protein Kinase C (aPKC) by Pseudosubstrate Displacement

(2012) Chiharu Graybill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals

(2012) Manuel Garber et al.   MOLECULAR CELL

Knockdown of Coronin-1C disrupts Rac1 activation and impairs tumorigenic potential in hepatocellular carcinoma cells

(2012) ZHI-GANG WANG et al.   ONCOLOGY REPORTS

An insect-specific P450 oxidative decarbonylase for cuticular hydrocarbon biosynthesis

(2012) Y. Qiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Honey Bee Viral Landscape Altered by a Parasitic Mite

(2012) S. J. Martin et al.   SCIENCE

LAMTOR1 depletion induces p53-dependent apoptosis via aberrant lysosomal activation

(2012) M Malek et al.   Cell Death & Disease

Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis

(2012) Alfiya Akhmetshina et al.   Nature Communications

Synergistic Parasite-Pathogen Interactions Mediated by Host Immunity Can Drive the Collapse of Honeybee Colonies

(2012) Francesco Nazzi et al.   PLoS Pathogens

p38 MAPK-dependent small HSP27 and αB-crystallin phosphorylation in regulation of myocardial function following cardioplegic arrest

(2011) Richard T. Clements et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Leucine nutrition in animals and humans: mTOR signaling and beyond

(2011) Fengna Li et al.   AMINO ACIDS

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Interpretation of Data Underlying the Link Between Colony Collapse Disorder (CCD) and an Invertebrate Iridescent Virus

(2011) Leonard J. Foster   MOLECULAR & CELLULAR PROTEOMICS

Salivary secretions from the honeybee mite, Varroa destructor: effects on insect haemocytes and preliminary biochemical characterization

(2011) E. H. RICHARDS et al.   PARASITOLOGY

Lack of Evidence for an Association between Iridovirus and Colony Collapse Disorder

(2011) Rafal Tokarz et al.   PLoS One

Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila

(2011) Michelle T. Juarez et al.   PLoS Genetics

HIV and SIV Induce Alterations in CNS CaMKII Expression and Activation

(2010) Ravi G. Gupta et al.   AMERICAN JOURNAL OF PATHOLOGY

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Bcl-6 and NF- B cistromes mediate opposing regulation of the innate immune response

(2010) G. D. Barish et al.   GENES & DEVELOPMENT

Ixodid tick salivary gland products target host wound healing growth factors

(2010) Valeria Hajnická et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Down-regulation of Bcl-2 is mediated by NF-κB activation inHelicobacter pylori-induced apoptosis of gastric epithelial cells

(2010) Sang Hui Chu et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Wnt signal transduction pathways

(2010) Yuko Komiya et al.   Organogenesis

RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway

(2009) Yu-Hsin Chiu et al.   CELL

Beyond Reactive Oxygen Species

(2009) Bradford G. Hill et al.   CIRCULATION RESEARCH

Nuclear Export of Smad2 and Smad3 by RanBP3 Facilitates Termination of TGF-β Signaling

(2009) Fangyan Dai et al.   DEVELOPMENTAL CELL

Modulation of TLR Signaling by Multiple MyD88-Interacting Partners Including Leucine-Rich Repeat Fli-I-Interacting Proteins

(2009) P. Dai et al.   JOURNAL OF IMMUNOLOGY

Identification of major royal jelly proteins in the brain of the honeybee Apis mellifera

(2009) Leonardo Gomes Peixoto et al.   JOURNAL OF INSECT PHYSIOLOGY

TGF-β signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3

(2009) Anjali Shukla et al.   NATURE CELL BIOLOGY

Changes in transcript abundance relating to colony collapse disorder in honey bees (Apis mellifera)

(2009) R. M. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADP+-dependent farnesol dehydrogenase, acorpora allataenzyme involved in juvenile hormone synthesis

(2009) Jaime G. Mayoral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localization of deformed wing virus (DWV) in the brains of the honeybee, Apis mellifera Linnaeus

(2009) Karan S Shah et al.   Virology Journal

Differential gene expression of the honey bee Apis mellifera associated with Varroa destructor infection

(2008) M Navajas et al.   BMC GENOMICS

BCL6 Represses Smad Signaling in Transforming Growth Factor-  Resistance

(2008) D. Wang et al.   CANCER RESEARCH

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Suppression of the Deubiquitinating Enzyme USP5 Causes the Accumulation of Unanchored Polyubiquitin and the Activation of p53

(2008) Saurabh Dayal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ran-Binding Protein 3 Phosphorylation Links the Ras and PI3-Kinase Pathways to Nucleocytoplasmic Transport

(2008) Sang-Oh Yoon et al.   MOLECULAR CELL

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

AIMP2/p38, the scaffold for the multi-tRNA synthetase complex, responds to genotoxic stresses via p53

(2008) J. M. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetic complications and dysregulated innate immunity

(2007) Dana et al.   Frontiers in Bioscience-Landmark