TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability
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Title
TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability
Authors
Keywords
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Journal
ONCOGENE
Volume 36, Issue 19, Pages 2715-2723
Publisher
Springer Nature
Online
2016-11-29
DOI
10.1038/onc.2016.424
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Related references
Note: Only part of the references are listed.- USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses
- (2014) Qiang Zou et al. NATURE IMMUNOLOGY
- Regulation of USP7/HAUSP in response to DNA damage: Yet another role for ATM
- (2012) Svetlana V. Khoronenkova et al. CELL CYCLE
- ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage
- (2012) Svetlana V. Khoronenkova et al. MOLECULAR CELL
- USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma
- (2012) Pieter J A Eichhorn et al. NATURE MEDICINE
- Non-Smad signaling pathways
- (2011) Yabing Mu et al. CELL AND TISSUE RESEARCH
- Role of Smads in TGFβ signaling
- (2011) Carl-Henrik Heldin et al. CELL AND TISSUE RESEARCH
- Switching TGFβ from a tumor suppressor to a tumor promoter
- (2011) Gareth J Inman CURRENT OPINION IN GENETICS & DEVELOPMENT
- TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs
- (2011) Tao Huang et al. EMBO JOURNAL
- USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1
- (2011) Xinna Zhang et al. EMBO JOURNAL
- USP15 is a deubiquitylating enzyme for receptor-activated SMADs
- (2011) Masafumi Inui et al. NATURE CELL BIOLOGY
- The dynamic roles of TGF-β in cancer
- (2010) Erik Meulmeester et al. JOURNAL OF PATHOLOGY
- The Ubiquitin-Specific Peptidase USP15 Regulates Human Papillomavirus Type 16 E6 Protein Stability
- (2009) R. M. Vos et al. JOURNAL OF VIROLOGY
- Breaking the chains: structure and function of the deubiquitinases
- (2009) David Komander et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TGFβ in Cancer
- (2008) Joan Massagué CELL
- Non-Smad pathways in TGF-β signaling
- (2008) Ying E Zhang CELL RESEARCH
- Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4
- (2008) P. Li et al. MOLECULAR AND CELLULAR BIOLOGY
- A Very Private TGF-β Receptor Embrace
- (2008) Joan Massagué MOLECULAR CELL
- Cooperative Assembly of TGF-β Superfamily Signaling Complexes Is Mediated by Two Disparate Mechanisms and Distinct Modes of Receptor Binding
- (2008) Jay Groppe et al. MOLECULAR CELL
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