Opposing effects of acute versus chronic inhibition of p53 on decitabine’s efficacy in myeloid neoplasms
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Title
Opposing effects of acute versus chronic inhibition of p53 on decitabine’s efficacy in myeloid neoplasms
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-03
DOI
10.1038/s41598-019-44496-6
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- (2016) G L Uy et al. LEUKEMIA
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- (2015) S Goyama et al. LEUKEMIA
- LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells
- (2015) Peidu Jiang et al. METHODS
- SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS
- (2014) D Inoue et al. LEUKEMIA
- Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
- (2013) Susumu Goyama et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2012) K. I. Leonova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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