Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia
Authors
Keywords
-
Journal
ONCOGENE
Volume 36, Issue 18, Pages 2589-2598
Publisher
Springer Nature
Online
2016-11-07
DOI
10.1038/onc.2016.416
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Xenograft models for normal and malignant stem cells
- (2015) S. Goyama et al. BLOOD
- Hematopoietic Differentiation Is Required for Initiation of Acute Myeloid Leukemia
- (2015) Min Ye et al. Cell Stem Cell
- UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO
- (2015) S Goyama et al. LEUKEMIA
- PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells
- (2015) Shiri Gur-Cohen et al. NATURE MEDICINE
- PAR1 inhibition suppresses the self-renewal and growth of A2B5-defined glioma progenitor cells and their derived gliomas in vivo
- (2015) R Auvergne et al. ONCOGENE
- Dysregulated protease activated receptor 1 (PAR1) promotes metastatic phenotype in breast cancer through HMGA2
- (2015) E Yang et al. ONCOGENE
- Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells
- (2014) F. Nakahara et al. BLOOD
- Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
- (2014) Liran I. Shlush et al. NATURE
- Proteinase-Activated Receptor 1 (PAR1) Regulates Leukemic Stem Cell Functions
- (2014) Nicole Bäumer et al. PLoS One
- Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
- (2014) M. R. Corces-Zimmerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A novel role for factor VIII and thrombin/PAR1 in regulating hematopoiesis and its interplay with the bone structure
- (2013) A. Aronovich et al. BLOOD
- Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
- (2013) Susumu Goyama et al. JOURNAL OF CLINICAL INVESTIGATION
- Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
- (2013) J. Gao et al. Science Signaling
- The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO
- (2012) F.-S. Chou et al. BLOOD
- Matrix metalloproteases and PAR1 activation
- (2012) K. M. Austin et al. BLOOD
- The transcriptional programme controlled by Runx1 during early embryonic blood development
- (2012) Yosuke Tanaka et al. DEVELOPMENTAL BIOLOGY
- Thrombin Receptor Regulates Hematopoiesis and Endothelial-to-Hematopoietic Transition
- (2012) Rui Yue et al. DEVELOPMENTAL CELL
- RUNX1Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures
- (2012) Jason H. Mendler et al. JOURNAL OF CLINICAL ONCOLOGY
- Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia
- (2012) M. Jan et al. Science Translational Medicine
- Hemostatic factors, innate immunity and malignancy
- (2012) Jay L. Degen et al. THROMBOSIS RESEARCH
- The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.
- (2012) Ethan Cerami et al. Cancer Discovery
- Increased expression of protease-activated receptor 1 (PAR-1) in human leukemias
- (2011) Camilla de S.B. Veiga et al. BLOOD CELLS MOLECULES AND DISEASES
- Transforming human blood stem and progenitor cells: A new way forward in leukemia modeling
- (2010) James C. Mulloy et al. CELL CYCLE
- The Wnt/ -Catenin Pathway Is Required for the Development of Leukemia Stem Cells in AML
- (2010) Y. Wang et al. SCIENCE
- Thrombin-stimulated growth factor and cytokine expression in osteoblasts is mediated by protease-activated receptor-1 and prostanoids
- (2009) Charles N. Pagel et al. BONE
- ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
- (2009) Yifang Hu et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
- (2008) Junping Wei et al. CANCER CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More