Targeting DNAJB9, a novel ER luminal co-chaperone, to rescue ΔF508-CFTR

Limitations to providing adult cystic fibrosis care in Europe: Results of a care centre survey

(2017) Susan Madge et al.   Journal of Cystic Fibrosis

Cystic fibrosis

(2016) J Stuart Elborn   LANCET

Members of the Hsp70 Family Recognize Distinct Types of Sequences to Execute ER Quality Control

(2016) Julia Behnke et al.   MOLECULAR CELL

Compartmentalized Accumulation of cAMP near Complexes of Multidrug Resistance Protein 4 (MRP4) and Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Contributes to Drug-induced Diarrhea

(2015) Changsuk Moon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NDRG1 promotes growth of hepatocellular carcinoma cells by directly interacting with GSK-3β and Nur77 to prevent β-catenin degradation

(2015) Wen-Jing Lu et al.   Oncotarget

Genetic Inhibition Of The Ubiquitin Ligase Rnf5 Attenuates Phenotypes Associated To F508del Cystic Fibrosis Mutation

(2015) Valeria Tomati et al.   Scientific Reports

Stabilizing Rescued Surface-Localized ΔF508 CFTR by Potentiation of Its Interaction with Na+/H+ Exchanger Regulatory Factor 1

(2014) Kavisha Arora et al.   BIOCHEMISTRY

The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control

(2014) Dimitra Athanasiou et al.   HUMAN MOLECULAR GENETICS

ER-associated degradation: Protein quality control and beyond

(2014) Annamaria Ruggiano et al.   JOURNAL OF CELL BIOLOGY

Probing of a Human Proteome Microarray With a Recombinant Pathogen Protein Reveals a Novel Mechanism by Which Hookworms Suppress B-Cell Receptor Signaling

(2014) Leon Tribolet et al.   JOURNAL OF INFECTIOUS DISEASES

RNF185 Is a Novel E3 Ligase of Endoplasmic Reticulum-associated Degradation (ERAD) That Targets Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

(2013) Elma El Khouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects

(2013) Jill M. Fritz et al.   MOLECULAR BIOLOGY OF THE CELL

A functional CFTR assay using primary cystic fibrosis intestinal organoids

(2013) Johanna F Dekkers et al.   NATURE MEDICINE

Ubiquitination and Degradation of CFTR by the E3 Ubiquitin Ligase MARCH2 through Its Association with Adaptor Proteins CAL and STX6

(2013) Jie Cheng et al.   PLoS One

The Cystic Fibrosis Intestine

(2013) R. C. De Lisle et al.   Cold Spring Harbor Perspectives in Medicine

An Adult Mouse Model of Vibrio cholerae-induced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera

(2013) Sutthipong Sawasvirojwong et al.   PLoS Neglected Tropical Diseases

FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability

(2012) Darren M. Hutt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERdj4 Protein Is a Soluble Endoplasmic Reticulum (ER) DnaJ Family Protein That Interacts with ER-associated Degradation Machinery

(2012) Chunwei Walter Lai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BiP prevents rod opsin aggregation

(2012) Dimitra Athanasiou et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms of CFTR Folding at the Endoplasmic Reticulum

(2012) Soo Jung Kim et al.   Frontiers in Pharmacology

ERp29 Regulates ΔF508 and Wild-type Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Trafficking to the Plasma Membrane in Cystic Fibrosis (CF) and Non-CF Epithelial Cells

(2011) Laurence Suaud et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel ER J-protein DNAJB12 Accelerates ER-associated Degradation of Membrane Proteins Including CFTR

(2010) Yo-hei Yamamoto et al.   CELL STRUCTURE AND FUNCTION

The Cystic Fibrosis-causing Mutation ΔF508 Affects Multiple Steps in Cystic Fibrosis Transmembrane Conductance Regulator Biogenesis

(2010) Patrick H. Thibodeau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Endoplasmic Reticulum–associated Degradation of the Epithelial Sodium Channel Requires a Unique Complement of Molecular Chaperones

(2010) Teresa M. Buck et al.   MOLECULAR BIOLOGY OF THE CELL

The endoplasmic reticulum–associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3–dependent degradation of nascent CFTRΔF508

(2010) Diane E. Grove et al.   MOLECULAR BIOLOGY OF THE CELL

A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation

(2010) Jurre Hageman et al.   MOLECULAR CELL

Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and ΔF508 CFTR

(2008) Tsukasa Okiyoneda et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulated release of ERdj3 from unfolded proteins by BiP

(2008) Yi Jin et al.   EMBO JOURNAL

Role of N-linked oligosaccharides in the biosynthetic processing of the cystic fibrosis membrane conductance regulator

(2008) X.-b. Chang et al.   JOURNAL OF CELL SCIENCE

Guidelines for Diagnosis of Cystic Fibrosis in Newborns through Older Adults: Cystic Fibrosis Foundation Consensus Report

(2008) Philip M. Farrell et al.   JOURNAL OF PEDIATRICS

ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C

(2008) Mei Dong et al.   MOLECULAR BIOLOGY OF THE CELL

Identification of novel substrates for Cdk5 and new targets for Cdk5 inhibitors using high-density protein microarrays

(2008) Cathrin Schnack et al.   PROTEOMICS