The endoplasmic reticulum–associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3–dependent degradation of nascent CFTRΔF508
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Title
The endoplasmic reticulum–associated Hsp40 DNAJB12 and Hsc70 cooperate to facilitate RMA1 E3–dependent degradation of nascent CFTRΔF508
Authors
Keywords
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Journal
MOLECULAR BIOLOGY OF THE CELL
Volume 22, Issue 3, Pages 301-314
Publisher
American Society for Cell Biology (ASCB)
Online
2010-12-10
DOI
10.1091/mbc.e10-09-0760
References
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Related references
Note: Only part of the references are listed.- The V510D Suppressor Mutation Stabilizes ΔF508-CFTR at the Cell Surface
- (2010) Tip W. Loo et al. BIOCHEMISTRY
- Regulatory Insertion Removal Restores Maturation, Stability and Function of ΔF508 CFTR
- (2010) Andrei A. Aleksandrov et al. JOURNAL OF MOLECULAR BIOLOGY
- The HSP70 chaperone machinery: J proteins as drivers of functional specificity
- (2010) Harm H. Kampinga et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis
- (2010) Chi Wang et al. PROTEIN SCIENCE
- N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic
- (2009) Rina Glozman et al. JOURNAL OF CELL BIOLOGY
- Mechanisms for Rescue of Correctable Folding Defects in CFTRΔF508
- (2009) Diane E. Grove et al. MOLECULAR BIOLOGY OF THE CELL
- Cooperative Assembly and Misfolding of CFTR Domains In Vivo
- (2009) Kai Du et al. MOLECULAR BIOLOGY OF THE CELL
- The ubiquitylation machinery of the endoplasmic reticulum
- (2009) Christian Hirsch et al. NATURE
- BAP31 Interacts with Sec61 Translocons and Promotes Retrotranslocation of CFTRΔF508 via the Derlin-1 Complex
- (2008) Bing Wang et al. CELL
- Dissecting the ER-Associated Degradation of a Misfolded Polytopic Membrane Protein
- (2008) Kunio Nakatsukasa et al. CELL
- Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces
- (2008) J.-P. Mornon et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation
- (2008) Luísa S. Pissarra et al. CHEMISTRY & BIOLOGY
- Gp78 Cooperates with RMA1 in Endoplasmic Reticulum-associated Degradation of CFTRΔF508
- (2008) Daisuke Morito et al. MOLECULAR BIOLOGY OF THE CELL
- Assembly and Misassembly of Cystic Fibrosis Transmembrane Conductance Regulator: Folding Defects Caused by Deletion of F508 Occur Before and After the Calnexin-dependent Association of Membrane Spanning Domain (MSD) 1 and MSD2
- (2008) Meredith F. N. Rosser et al. MOLECULAR BIOLOGY OF THE CELL
- Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
- (2008) A. W. R. Serohijos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding
- (2008) Adrian W. R. Serohijos et al. PLoS Computational Biology
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