Probing of a Human Proteome Microarray With a Recombinant Pathogen Protein Reveals a Novel Mechanism by Which Hookworms Suppress B-Cell Receptor Signaling

Probing the equatorial groove of the hookworm protein and vaccine candidate antigen, Na-ASP-2

(2014) Lyndel Mason et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

B Cell Depletion with Anti-CD79 mAbs Ameliorates Autoimmune Disease in MRL/lpr Mice

(2014) Y. Li et al.   JOURNAL OF IMMUNOLOGY

Anti-CD79 Antibody Induces B Cell Anergy That Protects against Autoimmunity

(2014) I. R. Hardy et al.   JOURNAL OF IMMUNOLOGY

Genome of the human hookworm Necator americanus

(2014) Yat T Tang et al.   NATURE GENETICS

Hookworm Excretory/Secretory Products Induce Interleukin-4 (IL-4)+IL-10+CD4+T Cell Responses and Suppress Pathology in a Mouse Model of Colitis

(2013) Ivana Ferreira et al.   INFECTION AND IMMUNITY

SBAL: a practical tool to generate and edit structure-based amino acid sequence alignments

(2012) Conan K. Wang et al.   BIOINFORMATICS

B-cell receptor: from resting state to activate

(2012) Bebhinn Treanor   IMMUNOLOGY

The hookworm pharmacopoeia for inflammatory diseases

(2012) Severine Navarro et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: Implications for the development of vaccines against helminths

(2012) David J. Diemert et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Trypsin resistance of the major peanut allergen Ara h 6 and allergenicity of the digestion products are abolished after selective disruption of disulfide bonds

(2012) Stéphane Hazebrouck et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Fusion of Na-ASP-2 with human immunoglobulin Fcγ abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE

(2012) B. ZHAN et al.   PARASITE IMMUNOLOGY

Characterising the Mucosal and Systemic Immune Responses to Experimental Human Hookworm Infection

(2012) Soraya Gaze et al.   PLoS Pathogens

Hookworm SCP/TAPS protein structure—A key to understanding host–parasite interactions and developing new interventions

(2011) Asiah Osman et al.   BIOTECHNOLOGY ADVANCES

Role of dendritic cells: a step forward for the hygiene hypothesis

(2011) Xi Yang et al.   Cellular & Molecular Immunology

Fungal proteomics: from identification to function

(2011) Sean Doyle   FEMS MICROBIOLOGY LETTERS

Monophosphorylation of CD79a and CD79b ITAM Motifs Initiates a SHIP-1 Phosphatase-Mediated Inhibitory Signaling Cascade Required for B Cell Anergy

(2011) Shannon K. O'Neill et al.   IMMUNITY

Twenty-First Century Progress Toward the Global Control of Human Hookworm Infection

(2011) Richard Bungiro et al.   Current Infectious Disease Reports

Production-scale purification of the recombinant major house dust mite allergen Der f 2 mutant C8/119S

(2010) Satoshi Koyanagi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Neutrophils Influence the Level of Antigen Presentation during the Immune Response to Protein Antigens in Adjuvants

(2010) C.-W. Yang et al.   JOURNAL OF IMMUNOLOGY

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Developing vaccines to combat hookworm infection and intestinal schistosomiasis

(2010) Peter J. Hotez et al.   NATURE REVIEWS MICROBIOLOGY

Structural and Functional Studies of Igαβ and Its Assembly with the B Cell Antigen Receptor

(2010) Sergei Radaev et al.   STRUCTURE

Suppression of Phosphatidylinositol 3,4,5-Trisphosphate Production Is a Key Determinant of B Cell Anergy

(2009) Cecille D. Browne et al.   IMMUNITY

Necator americanus Infection: A Possible Cause of Altered Dendritic Cell Differentiation and Eosinophil Profile in Chronically Infected Individuals

(2009) Ricardo T. Fujiwara et al.   PLoS Neglected Tropical Diseases

The secret(ion) life of worms

(2009) David McK Bird et al.   GENOME BIOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Accelerating and focusing protein-protein docking correlations using multi-dimensional rotational FFT generating functions

(2008) D. W. Ritchie et al.   BIOINFORMATICS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS

Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 Hookworm Vaccine in unexposed adults

(2008) Jeffrey M. Bethony et al.   VACCINE

Necator americanus: The Na-ASP-2 protein secreted by the infective larvae induces neutrophil recruitment in vivo and in vitro

(2007) Molly A. Bower et al.   EXPERIMENTAL PARASITOLOGY