Priming of Hypothalamic Ghrelin Signaling and Microglia Activation Exacerbate Feeding in Rats’ Offspring Following Maternal Overnutrition

Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways

(2019) Ruize Qu et al.   Scientific Reports

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Maternal Flavonoids Intake Reverts Depression-Like Behaviour in Rat Female Offspring

(2019) Ana de la Garza et al.   Nutrients

Maternal overnutrition by hypercaloric diets programs hypothalamic mitochondrial fusion and metabolic dysfunction in rat male offspring

(2018) Robbi E. Cardenas-Perez et al.   Nutrition & Metabolism

Inhibition of ghrelin o-acyltransferase attenuated lipotoxicity by inducing autophagy via AMPK–mTOR pathway

(2018) Shaoren Zhang et al.   Drug Design Development and Therapy

Obesity, Inflammation, Toll-Like Receptor 4 and Fatty Acids

(2018) Marcelo Rogero et al.   Nutrients

Maternal Lipid Concentrations during Early Pregnancy and Eating Behaviour and Energy Intake in the Offspring

(2018) Anna Dieberger et al.   Nutrients

Conditional microglial depletion in rats leads to reversible anorexia and weight loss by disrupting gustatory circuitry

(2018) Simone N. De Luca et al.   BRAIN BEHAVIOR AND IMMUNITY

The Ghrelin/GOAT System Regulates Obesity-Induced Inflammation in Male Mice

(2017) Rebecca E. Harvey et al.   ENDOCRINOLOGY

Association between increased visceral fat area and alterations in plasma fatty acid profile in overweight subjects: a cross-sectional study

(2017) Miso Kang et al.   Lipids in Health and Disease

Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a

(2017) Matteo Spinelli et al.   Nature Communications

Microglia activation due to obesity programs metabolic failure leading to type two diabetes

(2017) R Maldonado-Ruiz et al.   Nutrition & Diabetes

Central Modulation of Neuroinflammation by Neuropeptides and Energy-Sensing Hormones during Obesity

(2017) Roger Maldonado-Ruiz et al.   Biomed Research International

Experimental Models of Maternal Obesity and Neuroendocrine Programming of Metabolic Disorders in Offspring

(2017) Clare M. Reynolds et al.   Frontiers in Endocrinology

Neonatal overfeeding disrupts pituitary ghrelin signalling in female rats long-term; Implications for the stress response

(2017) Luba Sominsky et al.   PLoS One

Knockdown of Tlr4 in the Arcuate Nucleus Improves Obesity Related Metabolic Disorders

(2017) Yongli Zhao et al.   Scientific Reports

Maternal Western diet increases adiposity even in male offspring of obesity-resistant rat dams: early endocrine risk markers

(2016) Jennifer B. Frihauf et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control

(2016) Tina Djogo et al.   Cell Metabolism

Causal relationship between obesity-related traits and TLR4-driven responses at the maternal–fetal interface

(2016) Xiaohua Yang et al.   DIABETOLOGIA

Maternal Obesity in Pregnancy Developmentally Programs Adipose Tissue Inflammation in Young, Lean Male Mice Offspring

(2016) Maria Z. Alfaradhi et al.   ENDOCRINOLOGY

Sickness-Associated Anorexia: Mother Nature’s Idea of Immunonutrition?

(2016) Gustav van Niekerk et al.   MEDIATORS OF INFLAMMATION

Dietary saturated fat and monounsaturated fat have reversible effects on brain function and the secretion of pro-inflammatory cytokines in young women

(2016) Julie A. Dumas et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Maternal High-Fat Diet during Pregnancy and Lactation Influences Obestatin and Ghrelin Concentrations in Milk and Plasma of Wistar Rat Dams and Their Offspring

(2016) Monika Słupecka et al.   International Journal of Endocrinology

Sexually dimorphic brain fatty acid composition in low and high fat diet-fed mice

(2016) Carlos Rodriguez-Navas et al.   Molecular Metabolism

Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

(2015) Farhana Naznin et al.   JOURNAL OF ENDOCRINOLOGY

Genetic obesity alters recruitment of TANK-binding kinase 1 and AKT into hypothalamic lipid rafts domains

(2015) Ilse Delint-Ramirez et al.   NEUROCHEMISTRY INTERNATIONAL

Maternal obesity and the developmental programming of hypertension: a role for leptin

(2014) P. D. Taylor et al.   Acta Physiologica

Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term

(2014) Ilvana Ziko et al.   BRAIN BEHAVIOR AND IMMUNITY

Divergent Neuronal Circuitries Underlying Acute Orexigenic Effects of Peripheral or Central Ghrelin: Critical Role of Brain Accessibility

(2014) A. Cabral et al.   JOURNAL OF NEUROENDOCRINOLOGY

Neurobiology of food intake in health and disease

(2014) Gregory J. Morton et al.   NATURE REVIEWS NEUROSCIENCE

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia

(2014) Ted M. Hsu et al.   Frontiers in Aging Neuroscience

The Role of Ghrelin in Reward-Based Eating

(2012) Mario Perelló et al.   BIOLOGICAL PSYCHIATRY

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet

(2011) Brante P. Sampey et al.   Obesity

Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization

(2010) Patric J. D. Delhanty et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Perinatal Exposure to High-Fat Diet Programs Energy Balance, Metabolism and Behavior in Adulthood

(2010) Elinor L. Sullivan et al.   NEUROENDOCRINOLOGY

Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic β-cell line

(2010) Wei Wang et al.   REGULATORY PEPTIDES

A Double-Blind, Randomized Study of Minocycline for the Treatment of Negative and Cognitive Symptoms in Early-Phase Schizophrenia

(2009) Yechiel Levkovitz et al.   JOURNAL OF CLINICAL PSYCHIATRY

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Maternal High-Fat Diet and Fetal Programming: Increased Proliferation of Hypothalamic Peptide-Producing Neurons That Increase Risk for Overeating and Obesity

(2008) G.-Q. Chang et al.   JOURNAL OF NEUROSCIENCE