Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways

Ghrelin attenuates ultraviolet B radiation-induced impairment in capacities of epidermal stem cells

(2018) Yue-hui Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Ghrelin protects against osteoarthritis through interplay with Akt and NF-κB signaling pathways

(2018) Ruize Qu et al.   FASEB JOURNAL

Serum biomarkers of inflammation and adiposity in the LABS cohort: associations with metabolic disease and surgical outcomes

(2018) Robert W. O’Rourke et al.   INTERNATIONAL JOURNAL OF OBESITY

Signs of atopic dermatitis and contact dermatitis affected by distinct H2-haplotype in the NC/Nga genetic background

(2018) Kozo Ohkusu-Tsukada et al.   Scientific Reports

MAPK Phosphatase-1 Deficiency Exacerbates the Severity of Imiquimod-Induced Psoriasiform Skin Disease

(2018) Weiheng Zhao et al.   Frontiers in Immunology

Human Langerhans Cells with Pro-inflammatory Features Relocate within Psoriasis Lesions

(2018) Liv Eidsmo et al.   Frontiers in Immunology

Complement Activation in Inflammatory Skin Diseases

(2018) Jenny Giang et al.   Frontiers in Immunology

GDF11 Antagonizes Psoriasis-like Skin Inflammation via Suppression of NF-κB Signaling Pathway

(2018) Wenhan Wang et al.   INFLAMMATION

Effects of Ghrelin on the Apoptosis of Rheumatoid Arthritis Fibroblast-Like Synoviocyte MH7A Cells

(2018) Junxian Ma et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mangiferin antagonizes TNF-α-mediated inflammatory reaction and protects against dermatitis in a mice model

(2017) Yunpeng Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Ccr6 Is Dispensable for the Development of Skin Lesions Induced by Imiquimod despite its Effect on Epidermal Homing of IL-22–Producing Cells

(2017) Perrine M. Cochez et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway

(2017) Weiwei Li et al.   Oncotarget

Lipoxin A4 and its analog suppress inflammation by modulating HMGB1 translocation and expression in psoriasis

(2017) Xinxin Liu et al.   Scientific Reports

Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis

(2016) Thomas Marichal et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteomic Investigation of Dermal Fibroblasts Isolated from Affected and Unaffected Skin Samples from Patients with Limited Cutaneous Systemic Sclerosis: 2 Distinct Entities?

(2016) Claudio Corallo et al.   JOURNAL OF RHEUMATOLOGY

TNF and ROS Crosstalk in Inflammation

(2016) Heiko Blaser et al.   TRENDS IN CELL BIOLOGY

Contact dermatitis

(2016) Rabia Sofia Rashid et al.   BMJ-British Medical Journal

Contact dermatitis

(2016) Rabia Sofia Rashid et al.   BMJ-British Medical Journal

Cancer anorexia: hypothalamic activity and its association with inflammation and appetite-regulating peptides in lung cancer

(2016) Alessio Molfino et al.   Journal of Cachexia Sarcopenia and Muscle

Ghrelin accelerates wound healing through GHS-R1a-mediated MAPK-NF-κB/GR signaling pathways in combined radiation and burn injury in rats

(2016) Cong Liu et al.   Scientific Reports

Cumulative Incidence of, Risk Factors for and Outcome of Dermatological Complications of Anti-TNF Therapy in Inflammatory Bowel Disease: A 14-Year Experience

(2015) Estelle Fréling et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Randomized Phase II Study of the Anti-inflammatory Effect of Ghrelin During the Postoperative Period of Esophagectomy

(2015) Akihiro Takata et al.   ANNALS OF SURGERY

T Cell–Mediated Hypersensitivity Reactions to Drugs

(2015) Rebecca Pavlos et al.   Annual Review of Medicine

T cell responses in psoriasis and psoriatic arthritis

(2015) Marco Diani et al.   AUTOIMMUNITY REVIEWS

The global burden of psoriatic skin disease

(2015) K.L. Goff et al.   BRITISH JOURNAL OF DERMATOLOGY

Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice

(2015) Makiko Kawaguchi et al.   CANCER SCIENCE

Rebamipide suppresses TNF-α mediated inflammationin vitroand attenuates the severity of dermatitis in mice

(2015) Weiwei Li et al.   FEBS Journal

Coenzyme Q10 Suppresses TNF-α-Induced Inflammatory Reaction In Vitro and Attenuates Severity of Dermatitis in Mice

(2015) Weiwei Li et al.   INFLAMMATION

New approaches for predicting T cell–mediated drug reactions: A role for inducible and potentially preventable autoimmunity

(2015) Aaron W. Michels et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dynamics and Transcriptomics of Skin Dendritic Cells and Macrophages in an Imiquimod-Induced, Biphasic Mouse Model of Psoriasis

(2015) Dorothea Terhorst et al.   JOURNAL OF IMMUNOLOGY

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury

(2015) Alaa S. Awad et al.   KIDNEY INTERNATIONAL

Psoriasis

(2015) Wolf-Henning Boehncke et al.   LANCET

NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling

(2015) Yves Dondelinger et al.   MOLECULAR CELL

Commensal–dendritic-cell interaction specifies a unique protective skin immune signature

(2015) Shruti Naik et al.   NATURE

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

Correction: The Role of High Mobility Group Box 1 Protein (HMGB1) in the Immunopathology of Experimental Pulmonary Tuberculosis

(2015) Rogelio Hernández-Pando et al.   PLoS One

IκBζ is a key driver in the development of psoriasis

(2015) Claus Johansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate

(2015) Ramesh K. Krishnan et al.   Nature Communications

Aquaporin-3-mediated hydrogen peroxide transport is required for NF-κB signalling in keratinocytes and development of psoriasis

(2015) Mariko Hara-Chikuma et al.   Nature Communications

IgM rheumatoid factor amplifies the inflammatory response of macrophages induced by the rheumatoid arthritis-specific immune complexes containing anticitrullinated protein antibodies

(2014) Lætitia Laurent et al.   ANNALS OF THE RHEUMATIC DISEASES

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

Basophils regulate the recruitment of eosinophils in a murine model of irritant contact dermatitis

(2014) Chisa Nakashima et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Chronic allergic contact dermatitis promotes skin cancer

(2014) Shadmehr Demehri et al.   JOURNAL OF CLINICAL INVESTIGATION

Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity

(2014) Yuki Kagoya et al.   JOURNAL OF CLINICAL INVESTIGATION

Epidermal Th22 and Tc17 Cells Form a Localized Disease Memory in Clinically Healed Psoriasis

(2014) S. Cheuk et al.   JOURNAL OF IMMUNOLOGY

Nutritional State-Dependent Ghrelin Activation of Vasopressin Neurons via Retrograde Trans-Neuronal-Glial Stimulation of Excitatory GABA Circuits

(2014) J. Haam et al.   JOURNAL OF NEUROSCIENCE

Integrative Biology Approach Identifies Cytokine Targeting Strategies for Psoriasis

(2014) G. K. Perera et al.   Science Translational Medicine

Regulation of NF-κB by TNF family cytokines

(2014) Matthew S. Hayden et al.   SEMINARS IN IMMUNOLOGY

An ITAM-Syk-CARD9 signalling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells

(2014) Shinsuke Yasukawa et al.   Nature Communications

Multi-Scale Optical Imaging of the Delayed Type Hypersensitivity Reaction Attenuated by Rapamycin

(2014) Meijie Luo et al.   Theranostics

Relationships between Adipose Tissue and Psoriasis, with or without Arthritis

(2014) Éric Toussirot et al.   Frontiers in Immunology

The multiple factors affecting the association between atopic dermatitis and contact sensitization

(2013) J. P. Thyssen et al.   ALLERGY

Monocyte/Macrophage MMP-14 Modulates Cell Infiltration and T-Cell Attraction in Contact Dermatitis But Not in Murine Wound Healing

(2013) Anke Klose et al.   AMERICAN JOURNAL OF PATHOLOGY

Biomarkers in psoriasis and psoriatic arthritis

(2013) Federica Villanova et al.   ANNALS OF THE RHEUMATIC DISEASES

Ghrelin and bone

(2013) Patric J.D. Delhanty et al.   BIOFACTORS

Effect of acute and regular exercise on growth hormone secretagogue receptor-1a expression in human lymphocytes, T cell subpopulation and monocytes

(2013) Nicolette C. Bishop et al.   BRAIN BEHAVIOR AND IMMUNITY

Inactivation of BAD by IKK Inhibits TNFα-Induced Apoptosis Independently of NF-κB Activation

(2013) Jie Yan et al.   CELL

RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex

(2013) Fan Yao et al.   CELL RESEARCH

Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals

(2013) Malene W. Poulsen et al.   EUROPEAN JOURNAL OF NUTRITION

TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis

(2013) Boyi Liu et al.   FASEB JOURNAL

Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice

(2013) Yun-Peng Zhao et al.   FEBS LETTERS

Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

(2013) Cornelia Tillack et al.   GUT

Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin

(2013) Samira Tamoutounour et al.   IMMUNITY

Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium

(2013) Filip Van Hauwermeiren et al.   JOURNAL OF CLINICAL INVESTIGATION

CD8 T Cells Regulate Allergic Contact Dermatitis by Modulating CCR2–Dependent TNF/iNOS–Expressing Ly6C + CD11b + Monocytic Cells

(2013) Shu Zhen Chong et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

From the Medical Board of the National Psoriasis Foundation: The risk of cardiovascular disease in individuals with psoriasis and the potential impact of current therapies

(2013) Jeremy Hugh et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

TNF-α/TNFR1 signaling promotes gastric tumorigenesis through induction of Noxo1 and Gna14 in tumor cells

(2013) H Oshima et al.   ONCOGENE

IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

(2012) James G. Krueger et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation

(2012) Sofie Vandevyver et al.   JOURNAL OF CLINICAL INVESTIGATION

An Alternative Pathway of Imiquimod-Induced Psoriasis-Like Skin Inflammation in the Absence of Interleukin-17 Receptor A Signaling

(2012) Khalifa El Malki et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis

(2011) Gayathri K. Perera et al.   Annual Review of Pathology-Mechanisms of Disease

Characterization of factors that determine lentiviral vector tropism in skin tissue using an ex vivo model

(2011) Nikolai Kunicher et al.   JOURNAL OF GENE MEDICINE

Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF- -induced JNK activation and inflammation

(2011) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Whole-body deletion of LPS-induced TNF-  factor (LITAF) markedly improves experimental endotoxic shock and inflammatory arthritis

(2011) J. C. Merrill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevation of serum epidermal growth factor and interleukin 1 receptor antagonist in active psoriasis vulgaris

(2010) K.S. Anderson et al.   BRITISH JOURNAL OF DERMATOLOGY

Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis

(2010) Andrea Chiricozzi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis

(2009) L. van der Fits et al.   JOURNAL OF IMMUNOLOGY

Abrogation of High-Affinity IgE Receptor-Mediated Mast Cell Activation at the Effector Phase Prevents Contact Hypersensitivity to Oxazolone

(2009) Maiko Kobayashi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Psoriasis

(2009) Frank O. Nestle et al.   NEW ENGLAND JOURNAL OF MEDICINE