Protective effects of glucagon‐like peptide‐1 on cardiac remodeling by inhibiting oxidative stress through mammalian target of rapamycin complex 1/p70 ribosomal protein S6 kinase pathway in diabetes mellitus

IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045

(2018) N.H. Cho et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Andrographolide Ameliorates Diabetic Cardiomyopathy in Mice by Blockage of Oxidative Damage and NF-κB-Mediated Inflammation

(2018) Ershun Liang et al.   Oxidative Medicine and Cellular Longevity

Ginsenoside Rh2 Improves Cardiac Fibrosis via PPARδ–STAT3 Signaling in Type 1-Like Diabetic Rats

(2017) Shih-Hsiang Lo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Effects of Diabetes Induction on the Rat Heart: Differences in Oxidative Stress, Inflammatory Cells, and Fibrosis between Subendocardial and Interstitial Myocardial Areas

(2017) Maria C. Guido et al.   Oxidative Medicine and Cellular Longevity

Insights for Oxidative Stress and mTOR Signaling in Myocardial Ischemia/Reperfusion Injury under Diabetes

(2017) Dajun Zhao et al.   Oxidative Medicine and Cellular Longevity

Diabetic Cardiomyopathy: Current Approach and Potential Diagnostic and Therapeutic Targets

(2017) Georgiana-Emmanuela Gilca et al.   Journal of Diabetes Research

Novel protective mechanism of reducing renal cell damage in diabetes: Activation AMPK by AICAR increased NRF2/OGG1 proteins and reduced oxidative DNA damage

(2016) Samy L. Habib et al.   CELL CYCLE

Clinical Update: Cardiovascular Disease in Diabetes Mellitus

(2016) Cecilia C. Low Wang et al.   CIRCULATION

Mitochondrial Metabolism in Aging Heart

(2016) Edward J. Lesnefsky et al.   CIRCULATION RESEARCH

Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities

(2016) Ilaria Russo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

mTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and aging

(2015) Andras Perl   Annals of the New York Academy of Sciences

The Mitochondria in Diabetic Heart Failure: From Pathogenesis to Therapeutic Promise

(2015) Joel D. Schilling   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Dynamics in Diabetic Cardiomyopathy

(2015) Chad A. Galloway et al.   ANTIOXIDANTS & REDOX SIGNALING

Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy

(2015) Zoltán V. Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

miR-222 Is Necessary for Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

(2015) Xiaojun Liu et al.   Cell Metabolism

Metabolic Syndrome Abolishes Glucagon-Like Peptide 1 Receptor Agonist Stimulation of SERCA in Coronary Smooth Muscle

(2015) Stacey L. Dineen et al.   DIABETES

Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes

(2015) Petar M. Seferović et al.   EUROPEAN HEART JOURNAL

The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1–p70S6K–RPS6 signaling

(2015) Timothy D. Calamaras et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diabetic Cardiovascular Disease Induced by Oxidative Stress

(2015) Yosuke Kayama et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Pre-Treatment With Glucagon-Like Peptide-1 Protects Against Ischemic Left Ventricular Dysfunction and Stunning Without a Detected Difference in Myocardial Substrate Utilization

(2015) Liam M. McCormick et al.   JACC-Cardiovascular Interventions

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

(2015) Makoto Shigeto et al.   JOURNAL OF CLINICAL INVESTIGATION

Preclinical Left Ventricular Diastolic Dysfunction in Metabolic Syndrome

(2014) Nir Ayalon et al.   AMERICAN JOURNAL OF CARDIOLOGY

AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1

(2014) Yanh Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Glucagon-Like Peptide-1 Receptor Agonists for Diabetes Mellitus

(2014) Nathaniel R. Smilowitz et al.   CIRCULATION

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Folliculin (Flcn) inactivation leads to murine cardiac hypertrophy through mTORC1 deregulation

(2014) Yukiko Hasumi et al.   HUMAN MOLECULAR GENETICS

Diabetic cardiomyopathy and its mechanisms: Role of oxidative stress and damage

(2014) Quan Liu et al.   Journal of Diabetes Investigation

Glucagon-Like Peptide-1: Glucose Homeostasis and Beyond

(2013) Young Min Cho et al.   Annual Review of Physiology

Hyperglycemia-induced Oxidative Stress and its Role in Diabetes Mellitus Related Cardiovascular Diseases

(2013) Teresa Fiorentino et al.   CURRENT PHARMACEUTICAL DESIGN

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury

(2013) Assaad A. Eid et al.   DIABETES

Glucagon-Like Peptide-1 Protects Against Cardiac Microvascular Injury in Diabetes via a cAMP/PKA/Rho-Dependent Mechanism

(2013) D. Wang et al.   DIABETES

Pre-Clinical Diastolic Dysfunction

(2013) Siu-Hin Wan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury

(2012) Yi Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Diabetes: A Global Challenge With High Economic Burden for Public Health Systems and Society

(2012) Armando Arredondo   AMERICAN JOURNAL OF PUBLIC HEALTH

Diabetic cardiomyopathy: pathophysiology and clinical features

(2012) Takayuki Miki et al.   HEART FAILURE REVIEWS

GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases

(2012) Hari Hendarto et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice

(2011) Kimberley M. Mellor et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Glucagon-like peptide-1 and the exenatide analogue AC3174 improve cardiac function, cardiac remodeling, and survival in rats with chronic heart failure

(2010) Que Liu et al.   Cardiovascular Diabetology

Emerging cardiovascular actions of the incretin hormone glucagon-like peptide-1: potential therapeutic benefits beyond glycaemic control?

(2009) David J Grieve et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardioprotective and Vasodilatory Actions of Glucagon-Like Peptide 1 Receptor Are Mediated Through Both Glucagon-Like Peptide 1 Receptor–Dependent and –Independent Pathways

(2008) Kiwon Ban et al.   CIRCULATION