The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)

Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways

(2019) Jia-Min Zhang et al.   Cell Reports

FANCM limits ALT activity by restricting telomeric replication stress induced by deregulated BLM and R-loops

(2019) Bruno Silva et al.   Nature Communications

C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2

(2018) Xin D. Gao et al.   NATURE METHODS

Break-Induced Replication: The Where, The Why, and The How

(2018) J. Kramara et al.   TRENDS IN GENETICS

The concerted roles of FANCM and Rad52 in the protection of common fragile sites

(2018) Hailong Wang et al.   Nature Communications

Bi-allelic Recessive Loss-of-Function Variants in FANCM Cause Non-obstructive Azoospermia

(2018) Laura Kasak et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biallelic truncating FANCM mutations cause early-onset cancer but not Fanconi anemia

(2017) Massimo Bogliolo et al.   GENETICS IN MEDICINE

Homology Requirements and Competition between Gene Conversion and Break-Induced Replication during Double-Strand Break Repair

(2017) Anuja Mehta et al.   MOLECULAR CELL

Replication Fork Reversal: Players and Guardians

(2017) Annabel Quinet et al.   MOLECULAR CELL

Mechanism of tandem duplication formation in BRCA1-mutant cells

(2017) Nicholas A. Willis et al.   NATURE

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

(2017) Robin M Meyers et al.   NATURE GENETICS

TRF2 binds branched DNA to safeguard telomere integrity

(2017) Isabelle Schmutz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

FANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres

(2017) Xiaolei Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Lengthening of Telomeres: DNA Repair Pathways Converge

(2017) Alexander P. Sobinoff et al.   TRENDS IN GENETICS

TRF2 binds branched DNA to safeguard telomere integrity

(2017) Isabelle Schmutz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP

(2017) James M. Daley et al.   Cell Reports

The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage

(2017) Juan Lafuente-Barquero et al.   PLoS Genetics

Fanconi anemia proteins in telomere maintenance

(2016) Jaya Sarkar et al.   DNA REPAIR

Noncanonical views of homology-directed DNA repair

(2016) Priyanka Verma et al.   GENES & DEVELOPMENT

FANCD2 limits BLM-dependent telomere instability in the alternative lengthening of telomeres pathway

(2016) Heather Root et al.   HUMAN MOLECULAR GENETICS

Break-induced telomere synthesis underlies alternative telomere maintenance

(2016) Robert L. Dilley et al.   NATURE

FANCM interacts with PCNA to promote replication traverse of DNA interstrand crosslinks

(2016) Florian Rohleder et al.   NUCLEIC ACIDS RESEARCH

SMARCAL1 Resolves Replication Stress at ALT Telomeres

(2016) Kelli E. Cox et al.   Cell Reports

Bloom syndrome complex promotes FANCM recruitment to stalled replication forks and facilitates both repair and traverse of DNA interstrand crosslinks

(2016) Chen Ling et al.   Cell Discovery

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres

(2015) William C. Drosopoulos et al.   JOURNAL OF CELL BIOLOGY

The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription

(2015) Rebekka A. Schwab et al.   MOLECULAR CELL

Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis

(2014) Nam Woo Cho et al.   CELL

The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability

(2014) David Fox et al.   CELL RESEARCH

DNA2 Cooperates with the WRN and BLM RecQ Helicases to Mediate Long-range DNA End Resection in Human Cells

(2014) Andreas Sturzenegger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple Interactions of the Intrinsically Disordered Region between the Helicase and Nuclease Domains of the Archaeal Hef Protein

(2014) Sonoko Ishino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes

(2014) Qi Zhao et al.   Nature Communications

ATR-Dependent Phosphorylation of FANCM at Serine 1045 Is Essential for FANCM Functions

(2013) T. R. Singh et al.   CANCER RESEARCH

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

(2013) Luis Ignacio Toledo et al.   CELL

Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1

(2013) C. Elizabeth Caldon et al.   CELL CYCLE

The DNA Translocase FANCM/MHF Promotes Replication Traverse of DNA Interstrand Crosslinks

(2013) Jing Huang et al.   MOLECULAR CELL

Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

(2013) Marenda A. Wilson et al.   NATURE

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

(2013) Lorenzo Costantino et al.   SCIENCE

Substrate-Selective Repair and Restart of Replication Forks by DNA Translocases

(2013) Rémy Bétous et al.   Cell Reports

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity

(2012) Jean-Baptiste Vannier et al.   CELL

The DNA translocase activity of FANCM protects stalled replication forks

(2012) Andrew N. Blackford et al.   HUMAN MOLECULAR GENETICS

The Mph1 Helicase Can Promote Telomere Uncapping and Premature Senescence in Budding Yeast

(2012) Sarah Luke-Glaser et al.   PLoS One

Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome

(2012) K. A. Hoadley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FANCM Limits Meiotic Crossovers

(2012) W. Crismani et al.   SCIENCE

A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability

(2010) Zhijiang Yan et al.   MOLECULAR CELL

The FANCM/FAAP24 Complex Is Required for the DNA Interstrand Crosslink-Induced Checkpoint Response

(2010) Min Huang et al.   MOLECULAR CELL

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling

(2009) Sarah Luke-Glaser et al.   EMBO JOURNAL

Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M

(2009) Sietske T. Bakker et al.   HUMAN MOLECULAR GENETICS

FANCM Connects the Genome Instability Disorders Bloom's Syndrome and Fanconi Anemia

(2009) Andrew J. Deans et al.   MOLECULAR CELL

DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity

(2009) Jeremy D Henson et al.   NATURE BIOTECHNOLOGY

Spontaneous occurrence of telomeric DNA damage response in the absence of chromosome fusions

(2009) Anthony J Cesare et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair

(2008) Yutong Xue et al.   HUMAN MOLECULAR GENETICS

The Fanconi Anemia Protein FANCM Can Promote Branch Migration of Holliday Junctions and Replication Forks

(2008) Kerstin Gari et al.   MOLECULAR CELL

Remodeling of DNA replication structures by the branch point translocase FANCM

(2008) K. Gari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA