Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells

Bcl-2-associated athanogene 3 (BAG3) is an enhancer of small heat shock protein turnover via activation of autophagy in the heart

(2018) Yui Inomata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synapsin III is a key component of α-synuclein fibrils in Lewy bodies of PD brains

(2018) Francesca Longhena et al.   BRAIN PATHOLOGY

Network analysis of hippocampal neurons by microelectrode array in the presence of HIV-1 Tat and cocaine

(2018) Taha Mohseni Ahooyi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner

(2018) Maoping Tang et al.   NEUROBIOLOGY OF AGING

BAG3 Overexpression and Cytoprotective Autophagy Mediate Apoptosis Resistance in Chemoresistant Breast Cancer Cells

(2018) Chandan Kanta Das et al.   NEOPLASIA

Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease

(2018) Gaia Faustini et al.   ACTA NEUROPATHOLOGICA

Dysregulation of Neuronal Cholesterol Homeostasis upon Exposure to HIV-1 Tat and Cocaine Revealed by RNA-Sequencing

(2018) Taha Mohseni Ahooyi et al.   Scientific Reports

Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations

(2017) Andoni Echaniz-Laguna et al.   HUMAN MUTATION

BAG3-mediated proteostasis at a glance

(2017) Christina Klimek et al.   JOURNAL OF CELL SCIENCE

A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy

(2017) Yu-Lan Cao et al.   NEUROBIOLOGY OF AGING

Regulation of Neurotransmitter Release by Amyloid Precursor Protein Through Synapsin Phosphorylation

(2017) An Liu et al.   NEUROCHEMICAL RESEARCH

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases

(2017) Paola Rusmini et al.   Frontiers in Molecular Neuroscience

The Role of the Multifunctional BAG3 Protein in Cellular Protein Quality Control and in Disease

(2017) Elisabeth Stürner et al.   Frontiers in Molecular Neuroscience

SORLA regulates calpain-dependent degradation of synapsin

(2016) Daniela Hartl et al.   Alzheimers & Dementia

Inhibition of autophagy enhances dynamin inhibitor-induced apoptosis via promoting Bak activation and mitochondrial damage in human Jurkat T cells

(2016) Yoon Hee Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes

(2016) Farzaneh G. Tahrir et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Breaking BAG: The Co-Chaperone BAG3 in Health and Disease

(2016) Christian Behl   TRENDS IN PHARMACOLOGICAL SCIENCES

Molecular Mechanism of HIV-1 Tat Interacting with Human Dopamine Transporter

(2015) Yaxia Yuan et al.   ACS Chemical Neuroscience

 -synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons

(2015) M. Zaltieri et al.   JOURNAL OF CELL SCIENCE

Reduced phosphorylation of synapsin I in the hippocampus of Engrailed-2 knockout mice, a model for autism spectrum disorders

(2015) G. Provenzano et al.   NEUROSCIENCE

SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation

(2015) Leo T. -H. Tang et al.   Nature Communications

Interactive effects of cocaine on HIV infection: implication in HIV-associated neurocognitive disorder and neuroAIDS

(2015) Santosh Dahal et al.   Frontiers in Microbiology

BAG3 mRNA is present in synaptosomal polysomes of rat brain

(2014) Anna Paola Bruno et al.   CELL CYCLE

WW Domain of BAG3 Is Required for the Induction of Autophagy in Glioma Cells

(2014) Nana Merabova et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tension-induced autophagy

(2013) Anna Ulbricht et al.   Autophagy

BAG3-dependent noncanonical autophagy induced by proteasome inhibition in HepG2 cells

(2013) Bao-Qin Liu et al.   Autophagy

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

HIV-1 Tat protein variants: Critical role for the cysteine region in synaptodendritic injury

(2013) Sarah J. Bertrand et al.   EXPERIMENTAL NEUROLOGY

Fast Vesicle Transport Is Required for the Slow Axonal Transport of Synapsin

(2013) Y. Tang et al.   JOURNAL OF NEUROSCIENCE

B cell lymphoma in hiv transgenic mice

(2013) Sabrina Curreli et al.   Retrovirology

Autism-related behavioral abnormalities in synapsin knockout mice

(2012) Barbara Greco et al.   BEHAVIOURAL BRAIN RESEARCH

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

Identification of a synaptosome- associated form of BAG3 protein

(2011) Anna Paola Bruno et al.   CELL CYCLE

BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins

(2011) Martin Gamerdinger et al.   EMBO REPORTS

Medial prefrontal cortical synapsin II knock-down induces behavioral abnormalities in the rat: Examining synapsin II in the pathophysiology of schizophrenia

(2011) Bailey A. Dyck et al.   SCHIZOPHRENIA RESEARCH

BAG3 expression is sustained by FGF2 in neural progenitor cells and impacts cell proliferation

(2010) Antonio Gentilella et al.   CELL CYCLE

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

The co-chaperone BAG3 interacts with the cytosolic chaperonin CCT: New hints for actin folding

(2009) Bianca Fontanella et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

bag3 gene expression is regulated by heat shock factor 1

(2008) Silvia Franceschelli et al.   JOURNAL OF CELLULAR PHYSIOLOGY