Identification of evolutionary and kinetic drivers of NAD-dependent signaling
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Identification of evolutionary and kinetic drivers of NAD-dependent signaling
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 116, Issue 32, Pages 15957-15966
Publisher
Proceedings of the National Academy of Sciences
Online
2019-07-25
DOI
10.1073/pnas.1902346116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
- (2018) Sarah J. Mitchell et al. Cell Metabolism
- Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence
- (2018) Luis Rajman et al. Cell Metabolism
- Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
- (2018) Ling Liu et al. Cell Metabolism
- NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR
- (2018) Jun Yoshino et al. Cell Metabolism
- Elucidation of the trigonelline degradation pathway reveals previously undescribed enzymes and metabolites
- (2018) Nadia Perchat et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
- (2018) Christopher R. Martens et al. Nature Communications
- NNMT activation can contribute to the development of fatty liver disease by modulating the NAD+ metabolism
- (2018) Motoaki Komatsu et al. Scientific Reports
- A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
- (2018) Aimo Kannt et al. Scientific Reports
- De novo NAD+ biosynthetic impairment in acute kidney injury in humans
- (2018) Ali Poyan Mehr et al. NATURE MEDICINE
- Pharmacological bypass of NAD+ salvage pathway protects neurons from chemotherapy-induced degeneration
- (2018) Hui-wen Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes
- (2017) Rebecca Gupte et al. GENES & DEVELOPMENT
- NAD and the aging process: Role in life, death and everything in between
- (2017) Claudia C.S. Chini et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Nicotinamide N -Methyltransferase: More Than a Vitamin B3 Clearance Enzyme
- (2017) Pavlos Pissios TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer
- (2017) Jair Machado Espindola-Netto et al. Oncotarget
- Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy
- (2017) Nicolas Diguet et al. CIRCULATION
- Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice
- (2016) Kathryn F. Mills et al. Cell Metabolism
- The role of mitochondrial sirtuins in health and disease
- (2016) Brenna Osborne et al. FREE RADICAL BIOLOGY AND MEDICINE
- ETE 3: Reconstruction, Analysis, and Visualization of Phylogenomic Data
- (2016) Jaime Huerta-Cepas et al. MOLECULAR BIOLOGY AND EVOLUTION
- Biosensor reveals multiple sources for mitochondrial NAD+
- (2016) X. A. Cambronne et al. SCIENCE
- NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice
- (2016) H. Zhang et al. SCIENCE
- NAD+ repletion improves muscle function in muscular dystrophy and counters global PARylation
- (2016) D. Ryu et al. Science Translational Medicine
- Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice
- (2016) Samuel A.J. Trammell et al. Scientific Reports
- Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3
- (2015) Karolina Y. Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization
- (2015) Shangyu Hong et al. NATURE MEDICINE
- NAD+ in aging, metabolism, and neurodegeneration
- (2015) E. Verdin SCIENCE
- Discovery and characterization of novel small-molecule inhibitors targeting nicotinamide phosphoribosyltransferase
- (2015) Tian-Ying Xu et al. Scientific Reports
- Intracellular Mono-ADP-Ribosylation in Signaling and Disease
- (2015) Mareike Bütepage et al. Cells
- Sequence divergence and diversity suggests ongoing functional diversification of vertebrate NAD metabolism
- (2014) Toni I. Gossmann et al. DNA REPAIR
- Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity
- (2014) Daniel Kraus et al. NATURE
- SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information
- (2014) Marco Biasini et al. NUCLEIC ACIDS RESEARCH
- Effect of substrate competition in kinetic models of metabolic networks
- (2013) Sascha Schäuble et al. FEBS LETTERS
- Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
- (2013) Kathrin Schmeisser et al. Nature Chemical Biology
- NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
- (2013) Olesya A Ulanovskaya et al. Nature Chemical Biology
- Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models
- (2013) Bing Gong et al. NEUROBIOLOGY OF AGING
- The Evolutionary Portrait of Metazoan NAD Salvage
- (2013) João Carneiro et al. PLoS One
- The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
- (2012) Carles Cantó et al. Cell Metabolism
- NAD+biosynthesis and salvage - a phylogenetic perspective
- (2012) Toni I. Gossmann et al. FEBS Journal
- Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) as Messengers for Calcium Mobilization
- (2012) Hon Cheung Lee JOURNAL OF BIOLOGICAL CHEMISTRY
- Small-Molecule Allosteric Activators of Sirtuins
- (2011) David A. Sinclair et al. Annual Review of Pharmacology and Toxicology
- Pathway analysis of NAD+metabolism
- (2011) Luis F. de Figueiredo et al. BIOCHEMICAL JOURNAL
- Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice
- (2011) Jun Yoshino et al. Cell Metabolism
- CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy
- (2011) M. Cecilia Ljungberg et al. HUMAN MOLECULAR GENETICS
- Genomics-driven Reconstruction ofAcinetobacterNAD Metabolism
- (2010) Leonardo Sorci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Isoform-specific Targeting and Interaction Domains in Human Nicotinamide Mononucleotide Adenylyltransferases
- (2010) Corinna Lau et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response
- (2010) B Wang et al. ONCOGENE
- Improved side-chain torsion potentials for the Amber ff99SB protein force field
- (2010) Kresten Lindorff-Larsen et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes
- (2009) Chiao-Po Hsu et al. CIRCULATION RESEARCH
- Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo
- (2009) B. Beirowski et al. JOURNAL OF NEUROSCIENCE
- Microbial NAD Metabolism: Lessons from Comparative Genomics
- (2009) F. Gazzaniga et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPT
- (2009) E. S. Burgos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Emerging Roles of NAD+ and Its Metabolites in Cell Signaling
- (2009) F. Koch-Nolte et al. Science Signaling
- Weak Coupling of ATP Hydrolysis to the Chemical Equilibrium of Human Nicotinamide Phosphoribosyltransferase†
- (2008) Emmanuel S. Burgos et al. BIOCHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started