Consecutive seeding and transfer of genetic diversity in metastasis

Inferring parsimonious migration histories for metastatic cancers

(2018) Mohammed El-Kebir et al.   NATURE GENETICS

Minimal functional driver gene heterogeneity among untreated metastases

(2018) Johannes G. Reiter et al.   SCIENCE

Intratumor Heterogeneity and Circulating Tumor Cell Clusters

(2017) Zafarali Ahmed et al.   MOLECULAR BIOLOGY AND EVOLUTION

Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

(2017) Alvin P Makohon-Moore et al.   NATURE GENETICS

Between-region genetic divergence reflects the mode and tempo of tumor evolution

(2017) Ruping Sun et al.   NATURE GENETICS

The spatial organization of intra-tumour heterogeneity and evolutionary trajectories of metastases in hepatocellular carcinoma

(2017) Weiwei Zhai et al.   Nature Communications

Reconstructing metastatic seeding patterns of human cancers

(2017) Johannes G. Reiter et al.   Nature Communications

How Subclonal Modeling Is Changing the Metastatic Paradigm

(2016) Geoff Macintyre et al.   CLINICAL CANCER RESEARCH

Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer

(2016) Andrew McPherson et al.   NATURE GENETICS

Identification of neutral tumor evolution across cancer types

(2016) Marc J Williams et al.   NATURE GENETICS

Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

(2016) Kevin J. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metastasis as an evolutionary process

(2016) S. Turajlic et al.   SCIENCE

Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution

(2016) Ivana Bozic et al.   PLoS Computational Biology

The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”

(2016) Peter Savas et al.   PLOS MEDICINE

The evolutionary history of lethal metastatic prostate cancer

(2015) Gunes Gundem et al.   NATURE

Using tumour phylogenetics to identify the roots of metastasis in humans

(2015) Kamila Naxerova et al.   Nature Reviews Clinical Oncology

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

(2015) J. Zachary Sanborn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic Cancer Metastases Harbor Evidence of Polyclonality

(2015) R. Maddipati et al.   Cancer Discovery

The evolution of tumor metastasis during clonal expansion with alterations in metastasis driver genes

(2015) Kimiyo N. Yamamoto et al.   Scientific Reports

PyClone: statistical inference of clonal population structure in cancer

(2014) Andrew Roth et al.   NATURE METHODS

Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers

(2014) Ivana Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Evolution: Mathematical Models and Computational Inference

(2014) Niko Beerenwinkel et al.   SYSTEMATIC BIOLOGY

Spreaders and Sponges Define Metastasis in Lung Cancer: A Markov Chain Monte Carlo Mathematical Model

(2013) P. K. Newton et al.   CANCER RESEARCH

Estimating and interpreting FST: The impact of rare variants

(2013) G. Bhatia et al.   GENOME RESEARCH

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Evolutionary dynamics of cancer in response to targeted combination therapy

(2013) Ivana Bozic et al.   eLife

Computational Modeling of Pancreatic Cancer Reveals Kinetics of Metastasis Suggesting Optimum Treatment Strategies

(2012) Hiroshi Haeno et al.   CELL

The effect of one additional driver mutation on tumor progression

(2012) Johannes G. Reiter et al.   Evolutionary Applications

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

(2012) Luis A. Diaz Jr et al.   NATURE

Clonal evolution in cancer

(2012) Mel Greaves et al.   NATURE

Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines

(2012) Ashley A. Powell et al.   PLoS One

Does the cell number 109still really fit one gram of tumor tissue?

(2011) Ugo Del Monte   CELL CYCLE

Intratumor Heterogeneity in Evolutionary Models of Tumor Progression

(2011) Rick Durrett et al.   GENETICS

Clinical implications of cancer self-seeding

(2011) Elizabeth Comen et al.   Nature Reviews Clinical Oncology

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL