Quantifying Clonal and Subclonal Passenger Mutations in Cancer Evolution

Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity

(2015) Michael S. Rooney et al.   CELL

Mutant number distribution in an exponentially growing population

(2015) Peter Keller et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT

Characterizing inhibited tumor growth in stem-cell-driven non-spatial cancers

(2015) Ignacio A. Rodriguez-Brenes et al.   MATHEMATICAL BIOSCIENCES

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

(2015) Bartlomiej Waclaw et al.   NATURE

A Big Bang model of human colorectal tumor growth

(2015) Andrea Sottoriva et al.   NATURE GENETICS

A Multiscale Model Evaluates Screening for Neoplasia in Barrett’s Esophagus

(2015) Kit Curtius et al.   PLoS Computational Biology

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

(2014) M. Rajasagi et al.   BLOOD

Scaling Solution in the Large Population Limit of the General Asymmetric Stochastic Luria–Delbrück Evolution Process

(2014) David A. Kessler et al.   JOURNAL OF STATISTICAL PHYSICS

Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers

(2014) Ivana Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Evolution: Mathematical Models and Computational Inference

(2014) Niko Beerenwinkel et al.   SYSTEMATIC BIOLOGY

Population genetics of neutral mutations in exponentially growing cancer cell populations

(2013) Rick Durrett   ANNALS OF APPLIED PROBABILITY

Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

(2013) Dan A. Landau et al.   CELL

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

Large population solution of the stochastic Luria-Delbruck evolution model

(2013) D. A. Kessler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unwanted Evolution

(2013) I. Bozic et al.   SCIENCE

Cancer Genome Landscapes

(2013) B. Vogelstein et al.   SCIENCE

Tumor growth dynamics: insights into evolutionary processes

(2013) Ignacio A. Rodriguez-Brenes et al.   TRENDS IN ECOLOGY & EVOLUTION

Evolutionary dynamics of cancer in response to targeted combination therapy

(2013) Ivana Bozic et al.   eLife

Impact of Tumor Progression on Cancer Incidence Curves

(2012) E. G. Luebeck et al.   CANCER RESEARCH

The effect of one additional driver mutation on tumor progression

(2012) Johannes G. Reiter et al.   Evolutionary Applications

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Dynamics of targeted cancer therapy

(2012) Ivana Bozic et al.   TRENDS IN MOLECULAR MEDICINE

Reliable detection of subclonal single-nucleotide variants in tumour cell populations

(2012) Moritz Gerstung et al.   Nature Communications

Intratumor Heterogeneity in Evolutionary Models of Tumor Progression

(2011) Rick Durrett et al.   GENETICS

Fitness Conferred by BCR-ABL Kinase Domain Mutations Determines the Risk of Pre-Existing Resistance in Chronic Myeloid Leukemia

(2011) Kevin Leder et al.   PLoS One

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

Accumulation of driver and passenger mutations during tumor progression

(2010) I. Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of resistance and progression to disease during clonal expansion of cancer

(2009) Richard Durrett et al.   THEORETICAL POPULATION BIOLOGY

Comparative lesion sequencing provides insights into tumor evolution

(2008) S. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA