Ferritinophagic Flux Activation in CT26 Cells Contributed to EMT Inhibition Induced by a Novel Iron Chelator, DpdtpA

p53-Mediated PI3K/AKT/mTOR Pathway Played a Role in PtoxDpt-Induced EMT Inhibition in Liver Cancer Cell Lines

(2019) Yongli Li et al.   Oxidative Medicine and Cellular Longevity

ADAM9 mediates the interleukin-6-induced Epithelial–Mesenchymal transition and metastasis through ROS production in hepatoma cells

(2018) Yinying Dong et al.   CANCER LETTERS

Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation

(2018) Tengfei Huang et al.   Oxidative Medicine and Cellular Longevity

AMD3100 inhibits epithelial–mesenchymal transition, cell invasion, and metastasis in the liver and the lung through blocking the SDF‐1α/CXCR4 signaling pathway in prostate cancer

(2018) Wen‐Bin Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Vitamin D inhibits the epithelial-mesenchymal transition by a negative feedback regulation of TGF-β activity

(2018) Chiara Ricca et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Metformin attenuates cells stemness and epithelial‑mesenchymal transition in colorectal cancer cells by inhibiting the Wnt3a/β‑catenin pathway

(2018) Chu Zhang et al.   Molecular Medicine Reports

Epithelial-to-mesenchymal transition in FHC-silenced cells: the role of CXCR4/CXCL12 axis

(2017) I. Aversa et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Understanding the molecular mechanisms driving metastasis

(2017) Joan Massagué et al.   Molecular Oncology

Scavenging of reactive oxygen species by astaxanthin inhibits epithelial–mesenchymal transition in high glucose-stimulated mesothelial cells

(2017) Kazuaki Hara et al.   PLoS One

Iron depletion-induced downregulation of N-cadherin expression inhibits invasive malignant phenotypes in human esophageal cancer

(2016) Seishi Nishitani et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Deferoxamine-induced increase in the intracellular iron levels in highly aggressive breast cancer cells leads to increased cell migration by enhancing TNF-α-dependent NF-κB signaling and TGF-β signaling

(2016) Ping Liu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Copper Ion Attenuated the Antiproliferative Activity of Di-2-pyridylhydrazone Dithiocarbamate Derivative; However, There Was a Lack of Correlation between ROS Generation and Antiproliferative Activity

(2016) Tingting Wang et al.   MOLECULES

PARP3 controls TGFβ and ROS driven epithelial-to-mesenchymal transition and stemness by stimulating a TG2-Snail-E-cadherin axis

(2016) Olga Karicheva et al.   Oncotarget

The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway

(2015) Jiabei Wang et al.   Oncotarget

Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial–mesenchymal transition

(2014) Darius J.R. Lane et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition

(2014) Rik Derynck et al.   CURRENT OPINION IN CELL BIOLOGY

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds

(2013) Timur R Samatov et al.   Molecular Cancer

Lysosomal Iron, Iron Chelation, and Cell Death

(2012) Alexei Terman et al.   ANTIOXIDANTS & REDOX SIGNALING

Spatiotemporal Regulation of Epithelial-Mesenchymal Transition Is Essential for Squamous Cell Carcinoma Metastasis

(2012) Jeff H. Tsai et al.   CANCER CELL

Tumor microenvironment: a main actor in the metastasis process

(2012) Daniela Spano et al.   CLINICAL & EXPERIMENTAL METASTASIS

The Iron Chelators Dp44mT and DFO Inhibit TGF-β-induced Epithelial-Mesenchymal Transition via Up-Regulation of N-Myc Downstream-regulated Gene 1 (NDRG1)

(2012) Zhiqiang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EMT and Oxidative Stress: A Bidirectional Interplay Affecting Tumor Malignancy

(2011) Elisa Giannoni et al.   ANTIOXIDANTS & REDOX SIGNALING

Signaling Mechanism(S) of Reactive Oxygen Species in Epithelial-Mesenchymal Transition Reminiscent of Cancer Stem Cells in Tumor Progression

(2010) Zhiwei Wang et al.   Current Stem Cell Research & Therapy

Ferritin Heavy Chain–Mediated Iron Homeostasis and Subsequent Increased Reactive Oxygen Species Production Are Essential for Epithelial-Mesenchymal Transition

(2009) Ke-Hua Zhang et al.   CANCER RESEARCH

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epithelial–mesenchymal transition and the invasive potential of tumors

(2008) Nancy Gavert et al.   TRENDS IN MOLECULAR MEDICINE