Mutant p53 improves cancer cells’ resistance to endoplasmic reticulum stress by sustaining activation of the UPR regulator ATF6
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Title
Mutant p53 improves cancer cells’ resistance to endoplasmic reticulum stress by sustaining activation of the UPR regulator ATF6
Authors
Keywords
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Journal
ONCOGENE
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-16
DOI
10.1038/s41388-019-0878-3
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- (2018) L. Montibeller et al. CELL STRESS & CHAPERONES
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- (2018) Fiamma Mantovani et al. CELL DEATH AND DIFFERENTIATION
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- (2017) Eleonora Ingallina et al. NATURE CELL BIOLOGY
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- (2017) Kanaga Sabapathy et al. Nature Reviews Clinical Oncology
- Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
- (2016) Dawid Walerych et al. NATURE CELL BIOLOGY
- Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5
- (2016) Fotini Vogiatzi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis
- (2015) E. Chevet et al. Cancer Discovery
- Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway
- (2015) Takushi Namba et al. Oncotarget
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- (2015) Xiaoli Yao et al. PLoS One
- Endoplasmic Reticulum Stress in Malignancy
- (2014) Hanna J. Clarke et al. CANCER CELL
- TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
- (2014) L. Silwal-Pandit et al. CLINICAL CANCER RESEARCH
- Mutant p53 Reprograms TNF Signaling in Cancer Cells through Interaction with the Tumor Suppressor DAB2IP
- (2014) Giulio Di Minin et al. MOLECULAR CELL
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- (2013) Kwang Hong Tay et al. CELLULAR SIGNALLING
- Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress-Mitochondrial Dialog Triggering Lipotoxic Rodent and Human -Cell Apoptosis
- (2012) D. A. Cunha et al. DIABETES
- SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis
- (2011) D Li et al. CELL DEATH AND DIFFERENTIATION
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- (2011) M. Guan et al. CLINICAL CANCER RESEARCH
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47
- (2010) Karima Bourougaa et al. MOLECULAR CELL
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- (2008) Yusuke Adachi et al. CELL STRUCTURE AND FUNCTION
- ATF6 -Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
- (2008) D. M. Schewe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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