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Title
Restriction of HIV-1 and other retroviruses by TRIM5
Authors
Keywords
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Journal
NATURE REVIEWS MICROBIOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-07-16
DOI
10.1038/s41579-019-0225-2
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Note: Only part of the references are listed.- Immunoproteasome activation enables human TRIM5α restriction of HIV-1
- (2019) Jose M. Jimenez-Guardeño et al. Nature Microbiology
- Fuzziness in Protein Interactions—A Historical Perspective
- (2018) Monika Fuxreiter JOURNAL OF MOLECULAR BIOLOGY
- Nup153 Unlocks the Nuclear Pore Complex for HIV-1 Nuclear Translocation in Non-dividing Cells
- (2018) Cindy Buffone et al. JOURNAL OF VIROLOGY
- Editing of the human TRIM5 gene to introduce mutations with the potential to inhibit HIV-1
- (2018) Caroline Dufour et al. PLoS One
- Inhibitors of the HIV-1 capsid, a target of opportunity
- (2018) Stephanie K. Carnes et al. Current Opinion in HIV and AIDS
- Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis
- (2018) Chantal L Márquez et al. eLife
- IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis
- (2018) Donna L Mallery et al. eLife
- PF74 Reinforces the HIV-1 Capsid To Impair Reverse Transcription-Induced Uncoating
- (2018) Sanela Rankovic et al. JOURNAL OF VIROLOGY
- Inositol phosphates are assembly co-factors for HIV-1
- (2018) Robert A. Dick et al. NATURE
- Trivalent RING Assembly on Retroviral Capsids Activates TRIM5 Ubiquitination and Innate Immune Signaling
- (2018) Adam J. Fletcher et al. Cell Host & Microbe
- Retrovirus Restriction by TRIM5α: RINGside at a Cage Fight
- (2018) Wesley I. Sundquist et al. Cell Host & Microbe
- A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins
- (2018) Jeremy R. Keown et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations
- (2018) Caitlin M. Quinn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state
- (2018) Natacha Merindol et al. PLoS Pathogens
- A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV
- (2018) Molly OhAinle et al. eLife
- Stabilization of protein-protein interactions in drug discovery
- (2017) Sebastian A. Andrei et al. Expert Opinion on Drug Discovery
- Prevalence of gag mutations associated with in vitro resistance to capsid inhibitor GS-CA1 in HIV-1 antiretroviral-naive patients
- (2017) Marine Perrier et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Reverse Transcription Mechanically Initiates HIV-1 Capsid Disassembly
- (2017) Sanela Rankovic et al. JOURNAL OF VIROLOGY
- Dynamic conformational changes in the rhesus TRIM5α dimer dictate the potency of HIV-1 restriction
- (2017) Rajan Lamichhane et al. VIROLOGY
- TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition
- (2017) Marcin D. Roganowicz et al. PLoS Pathogens
- Identification of Interferon-Stimulated Genes with Antiretroviral Activity
- (2016) Melissa Kane et al. Cell Host & Microbe
- Crystal structure of the Trim5α Bbox2 domain from rhesus macaques describes a plastic oligomerisation interface
- (2016) Jeremy Russell Keown et al. JOURNAL OF STRUCTURAL BIOLOGY
- TRIM5α Degradation via Autophagy Is Not Required for Retroviral Restriction
- (2016) Sabrina Imam et al. JOURNAL OF VIROLOGY
- Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets
- (2016) Carla M. S. Ribeiro et al. NATURE
- HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis
- (2016) David A. Jacques et al. NATURE
- HIV-1 capsid uncoating initiates after the first strand transfer of reverse transcription
- (2016) Ophélie Cosnefroy et al. Retrovirology
- The structure and flexibility of conical HIV-1 capsids determined within intact virions
- (2016) Simone Mattei et al. SCIENCE
- Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site
- (2016) Chuang Liu et al. Nature Communications
- Characterisation of assembly and ubiquitylation by the RBCC motif of Trim5α
- (2016) Jeremy R. Keown et al. Scientific Reports
- Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α
- (2016) Jonathan M Wagner et al. eLife
- Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids
- (2016) Yen-Li Li et al. eLife
- Impact of TRIM5α in vivo
- (2015) Emi E. Nakayama et al. AIDS
- TRIM5 requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription
- (2015) A. J. Fletcher et al. EMBO JOURNAL
- Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene
- (2015) Ulrike Jung et al. HUMAN GENE THERAPY
- TRIM5α-Mediated Ubiquitin Chain Conjugation Is Required for Inhibition of HIV-1 Reverse Transcription and Capsid Destabilization
- (2015) Edward M. Campbell et al. JOURNAL OF VIROLOGY
- HIV-1 and interferons: who's interfering with whom?
- (2015) Tomas Doyle et al. NATURE REVIEWS MICROBIOLOGY
- HIV-1 capsid: the multifaceted key player in HIV-1 infection
- (2015) Edward M. Campbell et al. NATURE REVIEWS MICROBIOLOGY
- X-ray crystal structures of native HIV-1 capsid protein reveal conformational variability
- (2015) A. T. Gres et al. SCIENCE
- RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin
- (2015) Zinaida Yudina et al. Cell Reports
- The immunoproteasome and viral infection: a complex regulator of inflammation
- (2015) Mary K. McCarthy et al. Frontiers in Microbiology
- Recognition of the HIV Capsid by the TRIM5α Restriction Factor Is Mediated by a Subset of Pre-Existing Conformations of the TRIM5α SPRY Domain
- (2014) Dmytro B. Kovalskyy et al. BIOCHEMISTRY
- TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition
- (2014) Michael A. Mandell et al. DEVELOPMENTAL CELL
- Stabilized Human TRIM5α Protects Human T Cells From HIV-1 Infection
- (2014) Max W Richardson et al. MOLECULAR THERAPY
- Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
- (2014) Akash Bhattacharya et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice
- (2014) David C. Goldstone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer
- (2014) J. G. Sanchez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HIV-1 uncoating: connection to nuclear entry and regulation by host proteins
- (2014) Zandrea Ambrose et al. VIROLOGY
- A model for cofactor use during HIV-1 reverse transcription and nuclear entry
- (2014) Laura Hilditch et al. Current Opinion in Virology
- Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly
- (2014) Amanda J. Price et al. PLoS Pathogens
- Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid
- (2014) Ke Peng et al. eLife
- Using Antiubiquitin Antibodies to Probe the Ubiquitination State Within rhTRIM5α Cytoplasmic Bodies
- (2013) Cindy M. Danielson et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Capsid-binding retrovirus restriction factors: discovery, restriction specificity and implications for the development of novel therapeutics
- (2013) M. Sanz-Ramos et al. JOURNAL OF GENERAL VIROLOGY
- Rhesus Monkey TRIM5α SPRY Domain Recognizes Multiple Epitopes That Span Several Capsid Monomers on the Surface of the HIV-1 Mature Viral Core
- (2013) Nikolaos Biris et al. JOURNAL OF MOLECULAR BIOLOGY
- Retrovirus Restriction by TRIM5 Proteins Requires Recognition of Only a Small Fraction of Viral Capsid Subunits
- (2013) J. Shi et al. JOURNAL OF VIROLOGY
- A Comparison of Murine Leukemia Viruses That Escape from Human and Rhesus Macaque TRIM5 s
- (2013) S. Ohkura et al. JOURNAL OF VIROLOGY
- Generation of Rhesus Macaque-Tropic HIV-1 Clones That Are Resistant to Major Anti-HIV-1 Restriction Factors
- (2013) M. Nomaguchi et al. JOURNAL OF VIROLOGY
- Pressure from TRIM5 Contributes to Control of HIV-1 Replication by Individuals Expressing Protective HLA-B Alleles
- (2013) C. Granier et al. JOURNAL OF VIROLOGY
- A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen
- (2013) Quang Toan Pham et al. VIRUS RESEARCH
- Fates of Retroviral Core Components during Unrestricted and TRIM5-Restricted Infection
- (2013) Sebla B. Kutluay et al. PLoS Pathogens
- Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity
- (2013) Kevin R. McCarthy et al. PLoS Pathogens
- Assisted Evolution Enables HIV-1 to Overcome a High TRIM5α-Imposed Genetic Barrier to Rhesus Macaque Tropism
- (2013) Steven J. Soll et al. PLoS Pathogens
- TRIM5 alpha Drives SIVsmm Evolution in Rhesus Macaques
- (2013) Fan Wu et al. PLoS Pathogens
- Inhibition of Reverse Transcriptase Activity Increases Stability of the HIV-1 Core
- (2012) Y. Yang et al. JOURNAL OF VIROLOGY
- Generation of an HIV-1-Resistant Immune System with CD34+ Hematopoietic Stem Cells Transduced with a Triple-Combination Anti-HIV Lentiviral Vector
- (2012) J. E. Walker et al. JOURNAL OF VIROLOGY
- Diverse HIV viruses are targeted by a conformationally dynamic antiviral
- (2012) Matthew E C Caines et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural insight into HIV-1 capsid recognition by rhesus TRIM5
- (2012) H. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition module
- (2012) N. Biris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions
- (2012) Zana Lukic et al. Retrovirology
- Recruitment and Dynamics of Proteasome Association with rhTRIM5α Cytoplasmic Complexes During HIV-1 Infection
- (2012) Cindy M. Danielson et al. TRAFFIC
- Determinants of the Higher Order Association of the Restriction Factor TRIM5α and Other Tripartite Motif (TRIM) Proteins
- (2011) Xing Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RING Domain Mutations Uncouple TRIM5 Restriction of HIV-1 from Inhibition of Reverse Transcription and Acceleration of Uncoating
- (2011) A. Roa et al. JOURNAL OF VIROLOGY
- Modulation of TRIM5 Activity in Human Cells by Alternatively Spliced TRIM5 Isoforms
- (2011) E. Battivelli et al. JOURNAL OF VIROLOGY
- Contribution of E3-Ubiquitin Ligase Activity to HIV-1 Restriction by TRIM5 rh: Structure of the RING Domain of TRIM5
- (2011) M. Lienlaf et al. JOURNAL OF VIROLOGY
- Atomic-level modelling of the HIV capsid
- (2011) Owen Pornillos et al. NATURE
- TRIM5 is an innate immune sensor for the retrovirus capsid lattice
- (2011) Thomas Pertel et al. NATURE
- Complementary assays reveal a relationship between HIV-1 uncoating and reverse transcription
- (2011) A. E. Hulme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rhesus TRIM5α Disrupts the HIV-1 Capsid at the InterHexamer Interfaces
- (2011) Gongpu Zhao et al. PLoS Pathogens
- Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein
- (2011) Sadayuki Ohkura et al. PLoS Pathogens
- Chemically Controlled Protein Assembly: Techniques and Applications
- (2010) Adrian Fegan et al. CHEMICAL REVIEWS
- Generation of human TRIM5α mutants with high HIV-1 restriction activity
- (2010) Q T Pham et al. GENE THERAPY
- Homology-based Identification of Capsid Determinants That Protect HIV1 from Human TRIM5α Restriction
- (2010) Pierre V. Maillard et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TRIM5 Disrupts the Structure of Assembled HIV-1 Capsid Complexes In Vitro
- (2010) L. R. Black et al. JOURNAL OF VIROLOGY
- The Specificity of TRIM5 -Mediated Restriction Is Influenced by Its Coiled-Coil Domain
- (2010) P. V. Maillard et al. JOURNAL OF VIROLOGY
- Strain-Specific Differences in the Impact of Human TRIM5 , Different TRIM5 Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1
- (2010) E. Battivelli et al. JOURNAL OF VIROLOGY
- p62/Sequestosome-1 Associates with and Sustains the Expression of Retroviral Restriction Factor TRIM5
- (2010) C. O'Connor et al. JOURNAL OF VIROLOGY
- Small-Molecule Inhibition of Human Immunodeficiency Virus Type 1 Infection by Virus Capsid Destabilization
- (2010) J. Shi et al. JOURNAL OF VIROLOGY
- Hexagonal assembly of a restricting TRIM5 protein
- (2010) B. K. Ganser-Pornillos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α
- (2010) Ayumu Kuroishi et al. Retrovirology
- Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α
- (2010) Beatriz Pacheco et al. VIROLOGY
- Conformational Adaptation of Asian Macaque TRIMCyp Directs Lineage Specific Antiviral Activity
- (2010) Laura M. J. Ylinen et al. PLoS Pathogens
- HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention
- (2010) Wade S. Blair et al. PLoS Pathogens
- X-Ray Structures of the Hexameric Building Block of the HIV Capsid
- (2009) Owen Pornillos et al. CELL
- A B-Box 2 Surface Patch Important for TRIM5 Self-Association, Capsid Binding Avidity, and Retrovirus Restriction
- (2009) F. Diaz-Griffero et al. JOURNAL OF VIROLOGY
- Active site remodeling switches HIV specificity of antiretroviral TRIMCyp
- (2009) Amanda J Price et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Crystal structure of cyclophilin A complexed with a binding site peptide from the HIV-1 capsid protein
- (2009) Felix F. Vajdos et al. PROTEIN SCIENCE
- Ubiquitination of E3 ubiquitin ligase TRIM5α and its potential role
- (2008) Keiko Yamauchi et al. FEBS Journal
- Visualization of a proteasome-independent intermediate during restriction of HIV-1 by rhesus TRIM5α
- (2008) Edward M. Campbell et al. JOURNAL OF CELL BIOLOGY
- Structure of B-MLV Capsid Amino-terminal Domain Reveals Key Features of Viral Tropism, Gag Assembly and Core Formation
- (2008) Gulnahar B. Mortuza et al. JOURNAL OF MOLECULAR BIOLOGY
- Silencing of tripartite motif protein (TRIM) 5α mediated anti-HIV-1 activity by truncated mutant of TRIM5α
- (2008) Hikoichiro Maegawa et al. JOURNAL OF VIROLOGICAL METHODS
- The TRIM5 B-Box 2 Domain Promotes Cooperative Binding to the Retroviral Capsid by Mediating Higher-Order Self-Association
- (2008) X. Li et al. JOURNAL OF VIROLOGY
- Rhesus Macaque TRIM5 Alleles Have Divergent Antiretroviral Specificities
- (2008) S. J. Wilson et al. JOURNAL OF VIROLOGY
- Biochemical and Biophysical Characterization of a Chimeric TRIM21-TRIM5 Protein
- (2008) A. K. Kar et al. JOURNAL OF VIROLOGY
- Biochemical Characterization of a Recombinant TRIM5 Protein That Restricts Human Immunodeficiency Virus Type 1 Replication
- (2008) C. R. Langelier et al. JOURNAL OF VIROLOGY
- Independent evolution of an antiviral TRIMCyp in rhesus macaques
- (2008) S. J. Wilson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Implication of TRIMalpha and TRIMCyp in interferon-induced anti-retroviral restriction activities
- (2008) Laetitia Carthagena et al. Retrovirology
- A human TRIM5α B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus
- (2008) Felipe Diaz-Griffero et al. VIROLOGY
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