Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity

Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes

(2013) R. Malfavon-Borja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses

(2013) Alex A. Compton et al.   PLoS Pathogens

HIV-1 Capsid-Targeting Domain of Cleavage and Polyadenylation Specificity Factor 6

(2012) K. Lee et al.   JOURNAL OF VIROLOGY

Endogenous Lentiviruses in the Ferret Genome

(2012) J. Cui et al.   JOURNAL OF VIROLOGY

Gag-CA Q110D mutation elicits TRIM5-independent enhancement of HIV-1mt replication in macaque cells

(2012) Masako Nomaguchi et al.   MICROBES AND INFECTION

Endogenous Lentiviral Elements in the Weasel Family (Mustelidae)

(2012) G.-Z. Han et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structural insight into HIV-1 capsid recognition by rhesus TRIM5 

(2012) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the rhesus monkey TRIM5  PRYSPRY domain, the HIV capsid recognition module

(2012) N. Biris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

(2012) Amanda J. Price et al.   PLoS Pathogens

The Requirement for Nucleoporin NUP153 during Human Immunodeficiency Virus Type 1 Infection Is Determined by the Viral Capsid

(2011) K. A. Matreyek et al.   JOURNAL OF VIROLOGY

Unique Spectrum of Activity of Prosimian TRIM5  against Exogenous and Endogenous Retroviruses

(2011) N. Rahm et al.   JOURNAL OF VIROLOGY

Atomic-level modelling of the HIV capsid

(2011) Owen Pornillos et al.   NATURE

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

(2011) Thomas Pertel et al.   NATURE

A Single Amino Acid of Human Immunodeficiency Virus Type 2 Capsid Protein Affects Conformation of Two External Loops and Viral Sensitivity to TRIM5α

(2011) Tadashi Miyamoto et al.   PLoS One

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Rhesus TRIM5α Disrupts the HIV-1 Capsid at the Inter­Hexamer Interfaces

(2011) Gongpu Zhao et al.   PLoS Pathogens

Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein

(2011) Sadayuki Ohkura et al.   PLoS Pathogens

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Structural and Functional Analysis of Prehistoric Lentiviruses Uncovers an Ancient Molecular Interface

(2010) David C. Goldstone et al.   Cell Host & Microbe

Homology-based Identification of Capsid Determinants That Protect HIV1 from Human TRIM5α Restriction

(2010) Pierre V. Maillard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM5  Disrupts the Structure of Assembled HIV-1 Capsid Complexes In Vitro

(2010) L. R. Black et al.   JOURNAL OF VIROLOGY

Species-Specific Inhibition of Foamy Viruses from South American Monkeys by New World Monkey TRIM5  Proteins

(2010) B. Pacheco et al.   JOURNAL OF VIROLOGY

Evolution of the Antiretroviral Restriction Factor TRIMCyp in Old World Primates

(2010) Elizabeth A. Dietrich et al.   PLoS One

Hexagonal assembly of a restricting TRIM5  protein

(2010) B. K. Ganser-Pornillos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α

(2010) Ayumu Kuroishi et al.   Retrovirology

Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction

(2010) Ken Kono et al.   Retrovirology

HIV-2 capsids distinguish high and low virus load patients in a West African community cohort

(2010) Clayton O. Onyango et al.   VACCINE

Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5α

(2010) Beatriz Pacheco et al.   VIROLOGY

TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

(2010) Andrea Kirmaier et al.   PLOS BIOLOGY

Conformational Adaptation of Asian Macaque TRIMCyp Directs Lineage Specific Antiviral Activity

(2010) Laura M. J. Ylinen et al.   PLoS Pathogens

TRIM5α Modulates Immunodeficiency Virus Control in Rhesus Monkeys

(2010) So-Yon Lim et al.   PLoS Pathogens

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

NMR Structure of the N-Terminal Domain of Capsid Protein from the Mason–Pfizer Monkey Virus

(2009) Pavel Macek et al.   JOURNAL OF MOLECULAR BIOLOGY

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

Active site remodeling switches HIV specificity of antiretroviral TRIMCyp

(2009) Amanda J Price et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Modification of a loop sequence between α-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) vif and CA α-helices 4 and 5 loop improves replication in cynomolgus monkey cells

(2009) Ayumu Kuroishi et al.   Retrovirology

The structural biology of HIV assembly

(2008) Barbie K Ganser-Pornillos et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Tissue-specific restriction of cyclophilin A-independent HIV-1- and SIV-derived lentiviral vectors

(2008) C A Kahl et al.   GENE THERAPY

Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus

(2008) Gulnahar B. Mortuza et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of Postentry Restrictions to Mason-Pfizer Monkey Virus Infection in New World Monkey Cells

(2008) W. E. Diehl et al.   JOURNAL OF VIROLOGY

Rhesus Macaque TRIM5 Alleles Have Divergent Antiretroviral Specificities

(2008) S. J. Wilson et al.   JOURNAL OF VIROLOGY

Biochemical Characterization of a Recombinant TRIM5  Protein That Restricts Human Immunodeficiency Virus Type 1 Replication

(2008) C. R. Langelier et al.   JOURNAL OF VIROLOGY

TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis

(2008) G. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

(2008) C. A. Virgen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent evolution of an antiviral TRIMCyp in rhesus macaques

(2008) S. J. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution

(2008) R. J. Gifford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a RELIK orthologue in the European hare (Lepus europaeus) reveals a minimum age of 12 million years for the lagomorph lentiviruses

(2008) Z. Keckesova et al.   VIROLOGY

Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys

(2008) Ruchi M. Newman et al.   PLoS Pathogens