Development of Novel antimiRzymes for Targeted Inhibition of miR-21 Expression in Solid Cancer Cells

MicroRNA replacement therapy in cancer

(2019) Homa Mollaei et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Detailed Protein-SELEX Protocol Allowing Visual Assessments of Individual Steps for a High Success Rate

(2019) Tao Wang et al.   Human Gene Therapy Methods

Identification of Novel MicroRNAs and Their Diagnostic and Prognostic Significance in Oral Cancer

(2019) Falzone et al.   Cancers

Integrated analysis of colorectal cancer microRNA datasets: identification of microRNAs associated with tumor development

(2018) Luca Falzone et al.   Aging-US

Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregates in vitro

(2018) Madhuri Chakravarthy et al.   CHEMICAL COMMUNICATIONS

The regulatory role of microRNAs in angiogenesis-related diseases

(2018) Li-Li Sun et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Suppression of miR-21 Expression Inhibits Cell Proliferation and Migration of Liver Cancer Cells by Targeting Phosphatase and Tensin Homolog (PTEN)

(2018) Haiwei Liu et al.   MEDICAL SCIENCE MONITOR

Three decades of nucleic acid aptamer technologies: Lessons learned, progress and opportunities on aptamer development

(2018) Tao Wang et al.   BIOTECHNOLOGY ADVANCES

RNA-Cleaving DNAzymes: Old Catalysts with New Tricks for Intracellular and In Vivo Applications

(2018) JingJing Zhang   Catalysts

Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium

(2018) Luca Falzone et al.   Frontiers in Pharmacology

MiR-21: A key player in glioblastoma pathogenesis

(2017) Mohammad Sadegh Masoudi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Construction of a Bivalent Thrombin Binding Aptamer and Its Antidote with Improved Properties

(2017) Quintin Hughes et al.   MOLECULES

Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis

(2017) Madhuri Chakravarthy et al.   Scientific Reports

Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery

(2017) Dongxi Xiang et al.   Theranostics

Theranostic DNAzymes

(2017) Wenhu Zhou et al.   Theranostics

Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

(2017) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

(2017) Hadi AlShamaileh et al.   Scientific Reports

In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies

(2016) Farhana Lipi et al.   RNA Biology

Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells

(2016) James A. McCubrey et al.   Oncotarget

Inhibition of miR-21 in glioma cells using catalytic nucleic acids

(2016) Agnieszka Belter et al.   Scientific Reports

CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo

(2016) Hong Chang et al.   Scientific Reports

miR-21: A gene of dual regulation in breast cancer

(2015) CHUNFU ZHANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Probing the effect of minor groove interactions on the catalytic efficiency of DNAzymes 8–17 and 10–23

(2015) Michael H. Räz et al.   Molecular BioSystems

Smart functional nucleic acid chimeras: Enabling tissue specific RNA targeting therapy

(2015) Lukas J Aaldering et al.   RNA Biology

Cancer stem cell targeted therapy: progress amid controversies

(2015) Tao Wang et al.   Oncotarget

EpCAM Aptamer-mediated Survivin Silencing Sensitized Cancer Stem Cells to Doxorubicin in a Breast Cancer Model

(2015) Tao Wang et al.   Theranostics

MicroRNA-21 Promotes Glioblastoma Tumorigenesis by Down-regulating Insulin-like Growth Factor-binding Protein-3 (IGFBP3)

(2014) Chuan He Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

Multifunctional Nucleic Acids for Tumor Cell Treatment

(2014) Monika Pofahl et al.   Nucleic Acid Therapeutics

The transferrin receptor and the targeted delivery of therapeutic agents against cancer

(2011) Tracy R. Daniels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

(2011) Radek Lakomy et al.   CANCER SCIENCE

Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

(2011) Y. J. Yu et al.   Science Translational Medicine

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNA Expression Profiles Associated With Prognosis and Therapeutic Outcome in Colon Adenocarcinoma

(2008) Aaron J. Schetter et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Aptamer-based endocytosis of a lysosomal enzyme

(2008) C.-h. B. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA