Inhibition of miR-21 in glioma cells using catalytic nucleic acids

Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

(2015) Ulrich Lächelt et al.   CHEMICAL REVIEWS

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

RNA catalysis—is that it?

(2015) Timothy J. Wilson et al.   RNA

MicroRNA-21 (miR-21) Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by Targeting PTEN, RECK and Bcl-2 in Lung Squamous Carcinoma, Gejiu City, China

(2014) Long-feng Xu et al.   PLoS One

Mature MiRNAs Form Secondary Structure, which Suggests Their Function beyond RISC

(2014) Agnieszka Belter et al.   PLoS One

A New Short Oligonucleotide-Based Strategy for the Precursor-Specific Regulation of microRNA Processing by Dicer

(2013) Anna Kurzynska-Kokorniak et al.   PLoS One

Biomaterials in RNAi therapeutics: quo vadis?

(2013) Ernst Wagner   Biomaterials Science

Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules

(2012) Asako Murata et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Epigenetics in human gliomas

(2012) Simone Kreth et al.   CANCER LETTERS

MiR-21 Modulates hTERT Through a STAT3-Dependent Manner on Glioblastoma Cell Growth

(2012) Ying-Yi Wang et al.   CNS Neuroscience & Therapeutics

Mechanism of Antisense Oligonucleotide Interaction with Natural RNAs

(2012) R. Serikov et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Recent advances in the molecular understanding of glioblastoma

(2012) Fonnet E. Bleeker et al.   JOURNAL OF NEURO-ONCOLOGY

MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas

(2012) Simon Kjær Hermansen et al.   JOURNAL OF NEURO-ONCOLOGY

Glioblastoma—a moving target

(2012) Bengt Westermark   UPSALA JOURNAL OF MEDICAL SCIENCES

On the origin of glioma

(2012) Yiwen Jiang et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Integrated analysis of mutations, miRNA and mRNA expression in glioblastoma

(2011) Hua Dong et al.   BMC Systems Biology

MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients

(2011) Radek Lakomy et al.   CANCER SCIENCE

A specific miRNA signature in the peripheral blood of glioblastoma patients

(2011) Patrick Roth et al.   JOURNAL OF NEUROCHEMISTRY

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

(2011) A. B. Gaur et al.   NEURO-ONCOLOGY

BTECH: A Platform to Integrate Genomic, Transcriptomic and Epigenomic Alterations in Brain Tumors

(2011) Min Wang et al.   NEUROINFORMATICS

A Ten-microRNA Expression Signature Predicts Survival in Glioblastoma

(2011) Sujaya Srinivasan et al.   PLoS One

MicroRNA and Target Protein Patterns Reveal Physiopathological Features of Glioma Subtypes

(2011) Elodie Lages et al.   PLoS One

Therapeutic applications of ribozymes and riboswitches

(2010) Jérôme Mulhbacher et al.   CURRENT OPINION IN PHARMACOLOGY

Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry

(2010) María Berdasco et al.   DEVELOPMENTAL CELL

Analysis of microRNA knockouts in mice

(2010) C. Y. Park et al.   HUMAN MOLECULAR GENETICS

Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status

(2010) Xuan Zhou et al.   LABORATORY INVESTIGATION

Effect of high hydrostatic pressure on hydration and activity of ribozymes

(2010) Małgorzata Giel-Pietraszuk et al.   MOLECULAR BIOLOGY REPORTS

Modulation of microRNA function by synthetic ribozymes

(2010) Hemant Suryawanshi et al.   Molecular BioSystems

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

Integrative genome analysis reveals an oncomir/oncogene cluster regulating glioblastoma survivorship

(2010) H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Molecule Modifiers of the microRNA and RNA Interference Pathway

(2009) Alexander Deiters   AAPS Journal

Antagomirzymes: Oligonucleotide Enzymes That Specifically Silence MicroRNA Function

(2009) Vaibhav M. Jadhav et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

MicroRNA-21 targets LRRFIP1 and contributes to VM-26 resistance in glioblastoma multiforme

(2009) Yiming Li et al.   BRAIN RESEARCH

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Highly Active Low Magnesium Hammerhead Ribozyme

(2009) Agnieszka Fedoruk-Wyszomirska et al.   JOURNAL OF BIOCHEMISTRY

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

(2009) Fumitaka Takeshita et al.   MOLECULAR THERAPY

Small-Molecule Inhibitors of MicroRNA miR-21 Function

(2008) Kiranmai Gumireddy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal

(2008) J. Godlewski et al.   CANCER RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Stable knockdown of microRNA in vivo by lentiviral vectors

(2008) Bernhard Gentner et al.   NATURE METHODS

miR2Disease: a manually curated database for microRNA deregulation in human disease

(2008) Q. Jiang et al.   NUCLEIC ACIDS RESEARCH

Specific expression of long noncoding RNAs in the mouse brain

(2008) T. R. Mercer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE

Protein interactions and complexes in human microRNA biogenesis and function

(2007) Marjorie et al.   Frontiers in Bioscience-Landmark