Novel CB1-ligands maintain homeostasis of the endocannabinoid system in ω3- and ω6-long-chain-PUFA deficiency

Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics

(2018) Qing-Rong Liu et al.   ACTA PHARMACOLOGICA SINICA

When orexins meet cannabinoids: Bidirectional functional interactions

(2018) Fernando Berrendero et al.   BIOCHEMICAL PHARMACOLOGY

Crystal structures of agonist-bound human cannabinoid receptor CB1

(2017) Tian Hua et al.   NATURE

Cannabinoid Receptor Signaling in Central Regulation of Feeding Behavior: A Mini-Review

(2017) Marco Koch   Frontiers in Neuroscience

Feeding Behavior: Hypocretin/Orexin Neurons Act between Food Seeking and Eating

(2016) Xiao-Bing Gao et al.   CURRENT BIOLOGY

High-resolution crystal structure of the human CB1 cannabinoid receptor

(2016) Zhenhua Shao et al.   NATURE

A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: does the ratio really matter?

(2015) Stefano Marventano et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION

PUFAs: Structures, Metabolism and Functions

(2015) Anna Wiktorowska-Owczarek et al.   Advances in Clinical and Experimental Medicine

Nuclear Receptors, RXR, and the Big Bang

(2014) Ronald M. Evans et al.   CELL

Obesity resistance and deregulation of lipogenesis in Δ6-fatty acid desaturase (FADS2) deficiency

(2013) Wilhelm Stoffel et al.   EMBO REPORTS

Endocannabinoid system and pain: an introduction

(2013) James J. Burston et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

N-Palmitoyl-ethanolamine (PEA) Induces Peripheral Antinociceptive Effect by ATP-Sensitive K+-Channel Activation

(2012) Thiago Roberto Lima Romero et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Peripheral antinociceptive effect of anandamide and drugs that affect the endocannabinoid system on the formalin test in normal and streptozotocin-diabetic rats

(2012) Anne K. Schreiber et al.   NEUROPHARMACOLOGY

Docosahexaenoic Acid (DHA): An Ancient Nutrient for the Modern Human Brain

(2011) Joanne Bradbury   Nutrients

Endocannabinoid Binding to the Cannabinoid Receptors: What Is Known and What Remains Unknown

(2010) Patricia Reggio   CURRENT MEDICINAL CHEMISTRY

Dietary docosahexaenoic acid supplementation alters select physiological endocannabinoid-system metabolites in brain and plasma

(2010) JodiAnne T. Wood et al.   JOURNAL OF LIPID RESEARCH

TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus

(2010) Andrés E Chávez et al.   NATURE NEUROSCIENCE

Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression

(2010) W.C. Tu et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration

(2009) Chad K. Stroud et al.   JOURNAL OF LIPID RESEARCH

An alternate pathway to long-chain polyunsaturates: theFADS2gene product Δ8-desaturates 20:2n-6 and 20:3n-3

(2009) Woo Jung Park et al.   JOURNAL OF LIPID RESEARCH

Endocannabinoids May Mediate the Ability of (n-3) Fatty Acids to Reduce Ectopic Fat and Inflammatory Mediators in Obese Zucker Rats

(2009) Barbara Batetta et al.   JOURNAL OF NUTRITION

Influence of dietary fatty acids on endocannabinoid and N-acylethanolamine levels in rat brain, liver and small intestine

(2008) Andreas Artmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Δ6-Desaturase (FADS2) deficiency unveils the role of ω3- and ω6-polyunsaturated fatty acids

(2008) Wilhelm Stoffel et al.   EMBO JOURNAL

The Importance of the Omega-6/Omega-3 Fatty Acid Ratio in Cardiovascular Disease and Other Chronic Diseases

(2008) Artemis P. Simopoulos   EXPERIMENTAL BIOLOGY AND MEDICINE

Brain arachidonic and docosahexaenoic acid cascades are selectively altered by drugs, diet and disease

(2008) Stanley I. Rapoport   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS