Identification of novel mouse and rat CB1R isoforms and in silico modeling of human CB1R for peripheral cannabinoid therapeutics

Absence of cannabinoid 1 receptor in beta cells protects against high-fat/high-sugar diet-induced beta cell dysfunction and inflammation in murine islets

(2018) Isabel González-Mariscal et al.   DIABETOLOGIA

MicroRNAs-361-5p and miR-574-5p associate with human adipose morphology and regulate EBF1 expression in white adipose tissue

(2018) Yasmina Belarbi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Reading m 6 A in the Transcriptome: m 6 A-Binding Proteins

(2018) Deepak P. Patil et al.   TRENDS IN CELL BIOLOGY

Cannabinoid receptor 1/2 double-knockout mice develop epilepsy

(2017) Shane Rowley et al.   EPILEPSIA

Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide

(2017) Sarath Vijayakumar et al.   HUMAN MOLECULAR GENETICS

Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages

(2017) Inigo Ruiz de Azua et al.   JOURNAL OF CLINICAL INVESTIGATION

Synthesis of S -2-((S )-3-(4-chlorophenyl)-N '-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H -pyrazole-1-carboximidamido)-3-(methyl-d 3 )butanamide-d5 , octadeuterated JD5037

(2017) Malliga R. Iyer et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Discovery and characterization of two novel CB1 receptor splice variants with modified N-termini in mouse

(2017) Sabine Ruehle et al.   JOURNAL OF NEUROCHEMISTRY

Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD

(2017) Shiran Udi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Slowly Signaling G Protein–Biased CB2Cannabinoid Receptor Agonist LY2828360 Suppresses Neuropathic Pain with Sustained Efficacy and Attenuates Morphine Tolerance and Dependence

(2017) Xiaoyan Lin et al.   MOLECULAR PHARMACOLOGY

Crystal structures of agonist-bound human cannabinoid receptor CB1

(2017) Tian Hua et al.   NATURE

JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

(2017) Aziz Khan et al.   NUCLEIC ACIDS RESEARCH

Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling

(2017) Joseph Tam et al.   Molecular Metabolism

Crystal Structure of the Human Cannabinoid Receptor CB 1

(2016) Tian Hua et al.   CELL

Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice

(2016) Isabel González-Mariscal et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features

(2016) Yuan Zhou et al.   NUCLEIC ACIDS RESEARCH

m6A: Signaling for mRNA splicing

(2016) Samir Adhikari et al.   RNA Biology

Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism

(2016) Isabel González-Mariscal et al.   Scientific Reports

Endocannabinoid System Contributes to Liver Injury and Inflammation by Activation of Bone Marrow–Derived Monocytes/Macrophages in a CB1-Dependent Manner

(2015) Ping Mai et al.   JOURNAL OF IMMUNOLOGY

Non-Selective Cannabinoid Receptor Antagonists, Hinokiresinols Reduce Infiltration of Microglia/Macrophages into Ischemic Brain Lesions in Rat via Modulating 2-Arachidonolyglycerol-Induced Migration and Mitochondrial Activity

(2015) Angela M. A. Anthony Jalin et al.   PLoS One

Neuronal cell type–specific alternative splicing is regulated by the KH domain protein SLM1

(2014) Takatoshi Iijima et al.   JOURNAL OF CELL BIOLOGY

Species Differences in Cannabinoid Receptor 2 and Receptor Responses to Cocaine Self-Administration in Mice and Rats

(2014) Hai-Ying Zhang et al.   NEUROPSYCHOPHARMACOLOGY

Cannabinoid CB2receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice

(2014) Hai-Ying Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of molecular alterations in methamphetamine-activated Fos-expressing neurons from a single rat dorsal striatum using fluorescence-activated cell sorting (FACS)

(2013) Qing-Rong Liu et al.   JOURNAL OF NEUROCHEMISTRY

Crosstalk between Dopamine D2receptors and cannabinoid CB1receptors regulatesCNR1promoter activity via ERK1/2 signaling

(2013) Yao-Chang Chiang et al.   JOURNAL OF NEUROCHEMISTRY

The Endocannabinoid System and the Brain

(2012) Raphael Mechoulam et al.   Annual Review of Psychology

Hepatic Cannabinoid Receptor-1 Mediates Diet-Induced Insulin Resistance via Inhibition of Insulin Signaling and Clearance in Mice

(2012) Jie Liu et al.   GASTROENTEROLOGY

CNS effects of CB2 cannabinoid receptors: beyond neuro-immuno-cannabinoid activity

(2011) Emmanuel S Onaivi et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Genome-wide impact of a recently expanded microRNA cluster in mouse

(2011) G. X. Y. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropsychiatric Adverse Effects of Centrally Acting Antiobesity Drugs

(2010) Pradeep J. Nathan et al.   CNS Neuroscience & Therapeutics

Endocannabinoids in liver disease

(2010) Joseph Tam et al.   HEPATOLOGY

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes

(2009) N. Perwitz et al.   DIABETES OBESITY & METABOLISM

Species differences in cannabinoid receptor 2 (CNR2gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands

(2009) Q.-R. Liu et al.   GENES BRAIN AND BEHAVIOR

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Diadenosine tetraphosphate reduces toxicity caused by high-dose methamphetamine administration

(2009) Brandon K. Harvey et al.   NEUROTOXICOLOGY

Meta-analysis of cannabinoid ligand binding affinity and receptor distribution: interspecies differences

(2007) J M McPartland et al.   BRITISH JOURNAL OF PHARMACOLOGY