Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma

Whole-Genome Sequencing Reveals Diverse Models of Structural Variations in Esophageal Squamous Cell Carcinoma

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Cancer statistics in China, 2015

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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

(2016) Michele Ceccarelli et al.   CELL

Do short, frequent DNA sequence motifs mould the epigenome?

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Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma

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Global cancer statistics, 2012

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DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors

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Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution

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The Molecular Taxonomy of Primary Prostate Cancer

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The role of DNA methylation in directing the functional organization of the cancer epigenome

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The tumor area occupied by Tbet+ cells in deeply invading cervical cancer predicts clinical outcome

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Integrative analysis of 111 reference human epigenomes

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Paired exome analysis of Barrett's esophagus and adenocarcinoma

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Kinase inhibitors and monoclonal antibodies in oncology: clinical implications

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Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

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Tracking the Genomic Evolution of Esophageal Adenocarcinoma through Neoadjuvant Chemotherapy

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Multiple region whole-exome sequencing reveals dramatically evolving intratumor genomic heterogeneity in esophageal squamous cell carcinoma

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Cancer: Evolution Within a Lifetime

(2014) Marco Gerlinger et al.   Annual Review of Genetics

SAMBLASTER: fast duplicate marking and structural variant read extraction

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Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy

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A Novel Wnt Regulatory Axis in Endometrioid Endometrial Cancer

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Protocadherin 10 suppresses tumorigenesis and metastasis in colorectal cancer and its genetic loss predicts adverse prognosis

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Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

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Comprehensive molecular characterization of gastric adenocarcinoma

(2014) Adam J. Bass et al.   NATURE

Identification of genomic alterations in oesophageal squamous cell cancer

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Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Genetic landscape of esophageal squamous cell carcinoma

(2014) Yi-Bo Gao et al.   NATURE GENETICS

Genomic and molecular characterization of esophageal squamous cell carcinoma

(2014) De-Chen Lin et al.   NATURE GENETICS

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

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Genome-Wide Gene Expression Profile Analyses Identify CTTN as a Potential Prognostic Marker in Esophageal Cancer

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Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

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ABCB4 is frequently epigenetically silenced in human cancers and inhibits tumor growth

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Intratumor DNA Methylation Heterogeneity Reflects Clonal Evolution in Aggressive Prostate Cancer

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Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

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Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization

(2013) Z.-Z. Shi et al.   CLINICAL CANCER RESEARCH

PCDH10promoter hypermethylation is frequent in most histologic subtypes of mature lymphoid malignancies and occurs early in lymphomagenesis

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Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

DNA methylation dynamics in health and disease

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A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics

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Estimation of the Fraction of Cancer Cells in a Tumor DNA Sample Using DNA Methylation

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Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

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Infiltration of Lynch Colorectal Cancers by Activated Immune Cells Associates with Early Staging of the Primary Tumor and Absence of Lymph Node Metastases

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VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

Absolute quantification of somatic DNA alterations in human cancer

(2012) Scott L Carter et al.   NATURE BIOTECHNOLOGY

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

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Intratumor Heterogeneity: Seeing the Wood for the Trees

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Comparative Genomic Analysis of Esophageal Adenocarcinoma and Squamous Cell Carcinoma

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EPHA7 , a new target gene for 6q deletion in T-cell lymphoblastic lymphomas

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The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma

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Epigenomic program of Barrett's-associated neoplastic progression reveals possible involvement of insulin signaling pathways

(2011) Rachana Agarwal et al.   ENDOCRINE-RELATED CANCER

Inactivation of the putative suppressor gene DOK1 by promoter hypermethylation in primary human cancers

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Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer

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Temporal Dissection of Tumorigenesis in Primary Cancers

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Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis

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A method and server for predicting damaging missense mutations

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ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

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In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer

(2009) Franck Pagès et al.   JOURNAL OF CLINICAL ONCOLOGY

Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

(2009) Akiko Doi et al.   NATURE GENETICS

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

Methylation of Protocadherin 10, a Novel Tumor Suppressor, Is Associated With Poor Prognosis in Patients With Gastric Cancer

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