Loss of p27 kip1 suppresses the myocardial senescence caused by estrogen deficiency

Dietary nitrate protects submandibular gland from hyposalivation in ovariectomized rats via suppressing cell apoptosis

(2018) Yipu Xu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells

(2018) Alessandra Antunes dos Santos et al.   FOOD AND CHEMICAL TOXICOLOGY

Heart Failure as an Aging-Related Phenotype

(2018) Hiroyuki Morita et al.   International Heart Journal

PHLPP2 stabilization by p27 mediates its inhibition of bladder cancer invasion by promoting autophagic degradation of MMP2 protein

(2018) Minggang Peng et al.   ONCOGENE

A Review of Osteoporosis in the Older Adult

(2018) Paloma Alejandro et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

BMI-1 Mediates Estrogen-Deficiency-Induced Bone Loss by Inhibiting Reactive Oxygen Species Accumulation and T Cell Activation

(2017) Jinbo Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Blunting of cardioprotective actions of estrogen in female rodent heart linked to altered expression of cardiac tissue chymase and ACE2

(2017) Jaqueline S. da Silva et al.   JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM

Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1

(2017) Chien-Hsing Lee et al.   Oncotarget

Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway

(2017) Lili Wang et al.   Frontiers in Pharmacology

Activation of AMPK Attenuated Cardiac Fibrosis by Inhibiting CDK2 via p21/p27 and miR-29 Family Pathways in Rats

(2017) Hanping Qi et al.   Molecular Therapy-Nucleic Acids

Role of p16 INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells

(2017) Cristina Mas-Bargues et al.   Redox Biology

PTHrP Nuclear Localization and Carboxyl Terminus Sequences Modulate Dental and Mandibular Development in Part via the Action of p27

(2016) Wen Sun et al.   ENDOCRINOLOGY

Effect of Age, Estrogen Status, and Late-Life GPER Activation on Cardiac Structure and Function in the Fischer344×Brown Norway Female Rat

(2016) Allan K. Alencar et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Effect of Phosphatase and Tensin Homologue on Chromosome 10 on Angiotensin II-Mediated Proliferation, Collagen Synthesis, and Akt/P27 Signaling in Neonatal Rat Cardiac Fibroblasts

(2016) Ling Nie et al.   Biomed Research International

Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106

(2016) Tao Luo et al.   PLoS One

Programmed cell death in aging

(2015) John Tower   AGEING RESEARCH REVIEWS

Bmi-1 Regulates Extensive Erythroid Self-Renewal

(2015) Ah Ram Kim et al.   Stem Cell Reports

Increased activity of osteocyte autophagy in ovariectomized rats and its correlation with oxidative stress status and bone loss

(2014) Yuehua Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration

(2014) D. Zhang et al.   JOURNAL OF CELL SCIENCE

p27kip1 haplo-insufficiency improves cardiac function in early-stages of myocardial infarction by protecting myocardium and increasing angiogenesis by promoting IKK activation

(2014) Ningtian Zhou et al.   Scientific Reports

Decreased proliferation of aging tenocytes is associated with down-regulation of cellular senescence-inhibited gene and up-regulation of p27

(2011) Wen-Chung Tsai et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

A woman's journey through the reproductive, transitional and postmenopausal periods of life: Impact on cardiovascular and musculo-skeletal risk and the role of estrogen replacement

(2011) John C. Stevenson   MATURITAS

Novel Markers of Left Ventricular Hypertrophy in Uremia

(2010) Hironori Nakamura et al.   AMERICAN JOURNAL OF NEPHROLOGY

Effects of growth hormone, melatonin, oestrogens and phytoestrogens on the oxidized glutathione (GSSG)/reduced glutathione (GSH) ratio and lipid peroxidation in aged ovariectomized rats

(2010) Isabel Baeza et al.   BIOGERONTOLOGY

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

(2010) Ismail Hassan Ismail et al.   JOURNAL OF CELL BIOLOGY

FoxM1c Counteracts Oxidative Stress-induced Senescence and Stimulates Bmi-1 Expression

(2008) Samuel K. M. Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY