Antioxidant Effect of Fructus Ligustri Lucidi Aqueous Extract in Ovariectomized Rats Is Mediated through Nox4-ROS-NF-κB Pathway

The New Synthetic H2S-Releasing SDSS Protects MC3T3-E1 Osteoblasts against H2O2-Induced Apoptosis by Suppressing Oxidative Stress, Inhibiting MAPKs, and Activating the PI3K/Akt Pathway

(2017) Xiaofei Yan et al.   Frontiers in Pharmacology

Nrf2 protects mitochondrial decay by oxidative stress

(2016) Joshua Strom et al.   FASEB JOURNAL

Raloxifene and Tamoxifen Reduce PARP Activity, Cytokine and Oxidative Stress Levels in the Brain and Blood of Ovariectomized Rats

(2016) Betül Yazğan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

JiangTang XiaoKe granule attenuates cathepsin K expression and improves IGF-1 expression in the bone of high fat diet induced KK-Ay diabetic mice

(2016) Yubo Guo et al.   LIFE SCIENCES

Fructus Ligustri Lucidi ethanol extract inhibits osteoclastogenesis in RAW264.7 cells via the RANKL signaling pathway

(2016) Dan Xu et al.   Molecular Medicine Reports

Antioxidant Capacities of Hot Water Extracts and Endopolysaccharides of Selected Chinese Medicinal Fruits

(2016) Sang Jeong et al.   Cancers

Spiranthes sinensis Suppresses Production of Pro-Inflammatory Mediators by Down-Regulating the NF-κB Signaling Pathway and Up-Regulating HO-1/Nrf2 Anti-Oxidant Protein

(2015) Pei-Hsin Shie et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Regulation of Mitochondrial Biogenesis and Its Intersection with Inflammatory Responses

(2015) Anne D. Cherry et al.   ANTIOXIDANTS & REDOX SIGNALING

Gastrodin: An ancient Chinese herbal medicine as a source for anti-osteoporosis agents via reducing reactive oxygen species

(2015) Qiang Huang et al.   BONE

Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

(2015) Danielle A. Callaway et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2 O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats

(2015) Chao Fu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effect of Fructus Ligustri Lucidi on osteoblastic like cell-line MC3T3-E1

(2015) Qin Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

Inhibitory effect of zinc on the advanced glycation end product-induced apoptosis of mouse osteoblastic cells

(2015) MINGYUE XIONG et al.   Molecular Medicine Reports

Stereological study of the effect of black olive hydroalcoholic extract on osteoporosis in vertebra and tibia in ovariectomized rats

(2015) A. Noorafshan et al.   OSTEOPOROSIS INTERNATIONAL

Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK Signalling

(2015) Dinesh Thummuri et al.   PHARMACOLOGICAL RESEARCH

Naringin prevents ovariectomy-induced osteoporosis and promotes osteoclasts apoptosis through the mitochondria-mediated apoptosis pathway

(2014) Fengbo Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ginsenoside-Rb2 displays anti-osteoporosis effects through reducing oxidative damage and bone-resorbing cytokines during osteogenesis

(2014) Qiang Huang et al.   BONE

NADPH oxidase 4 represents a potential target for the treatment of osteoporosis

(2014) Paula Hoff et al.   Cellular & Molecular Immunology

Beneficial Effects of Traditional Chinese Medicine on the Treatment of Osteoporosis on Ovariectomised Rat Models

(2014) Pamela Rufus et al.   CURRENT DRUG TARGETS

Effects of total lignans from Eucommia ulmoides barks prevent bone loss in vivo and in vitro

(2014) Rong Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protective effects of water fraction of Fructus Ligustri Lucidi extract against hypercalciuria and trabecular bone deterioration in experimentally type 1 diabetic mice

(2014) Yan Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Involvement of oxidative stress, Nuclear Factor kappa B and the Ubiquitin proteasomal pathway in dysferlinopathy

(2014) Dhanarajan Rajakumar et al.   LIFE SCIENCES

Combination therapy of Chinese herbal medicine Fructus Ligustri Lucidi with high calcium diet on calcium imbalance induced by ovariectomy in mice

(2014) Yan Zhang et al.   PHARMACEUTICAL BIOLOGY

Strontium ranelate treatment improves oxidative damage in osteoporotic rat model

(2014) Serap Yalin et al.   Pharmacological Reports

Nicotinamide Adenine Dinucleotide Phosphate Oxidase Is Differentially Regulated in Normal Myometrium Versus Leiomyoma

(2014) Nicole M. Fletcher et al.   Reproductive Sciences

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

(2014) Anu Rahal et al.   Biomed Research International

Oxidative Stress and Bone Resorption Interplay as a Possible Trigger for Postmenopausal Osteoporosis

(2014) Carlo Cervellati et al.   Biomed Research International

Osteoporosis and alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling

(2014) Carolin Cornelius et al.   Frontiers in Pharmacology

Fructus ligustri lucidi Ethanol Extract Improves Bone Mineral Density and Properties Through Modulating Calcium Absorption-Related Gene Expression in Kidney and Duodenum of Growing Rats

(2013) Xin Feng et al.   CALCIFIED TISSUE INTERNATIONAL

Pomegranate and its derivatives can improve bone health through decreased inflammation and oxidative stress in an animal model of postmenopausal osteoporosis

(2013) Mélanie Spilmont et al.   EUROPEAN JOURNAL OF NUTRITION

Fructus Ligustri Lucidi (FLL) ethanol extract increases bone mineral density and improves bone properties in growing female rats

(2013) Ying Lyu et al.   JOURNAL OF BONE AND MINERAL METABOLISM

NADPH oxidase 4 limits bone mass by promoting osteoclastogenesis

(2013) Claudia Goettsch et al.   JOURNAL OF CLINICAL INVESTIGATION

Plumbagin Ameliorates Diabetic Nephropathy via Interruption of Pathways that Include NOX4 Signalling

(2013) Rachel Yong et al.   PLoS One

Zinc Inhibits H2O2-Induced MC3T3-E1 Cells Apoptosis via MAPK and PI3K/AKT Pathways

(2012) Dan Liang et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Bioactivity-guided Isolation of Antiosteoporotic Compounds fromLigustrum lucidum

(2012) Qianfeng Chen et al.   PHYTOTHERAPY RESEARCH

Improvement of calcium balance by Fructus Ligustri Lucidi extract in mature female rats was associated with the induction of serum parathyroid hormone levels

(2011) Xiao-Li Dong et al.   BRITISH JOURNAL OF NUTRITION

Antioxidant phenolic profile from ethyl acetate fraction of Fructus Ligustri Lucidi with protection against hydrogen peroxide-induced oxidative damage in SH-SY5Y cells

(2011) Heng-Yin Ju et al.   FOOD AND CHEMICAL TOXICOLOGY

Increased blood oxidative stress in experimental menopause rat model: the effects of vitamin A low-dose supplementation upon antioxidant status in bilateral ovariectomized rats

(2011) Guilherme Antônio Behr et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Bcl-2 Family Proteins as Therapeutic Targets

(2010) Peter E. Czabotar et al.   CURRENT PHARMACEUTICAL DESIGN

Update on Estrogens and the Skeleton

(2010) Sundeep Khosla   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Ethanol extract of Fructus Ligustri Lucidi increases circulating 1,25-dihydroxyvitamin D3 by inducing renal 25-hydroxyvitamin D-1α hydroxylase activity

(2010) Xiao-Li Dong et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

NADPH oxidase 4 (Nox4) is a major source of oxidative stress in the failing heart

(2010) J. Kuroda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoprotective effects of Fructus Ligustri Lucidi aqueous extract in aged ovariectomized rats

(2010) Chun Ko et al.   Chinese Medicine

8-hydroxy-2′ -deoxyguanosine (8-OHdG): A Critical Biomarker of Oxidative Stress and Carcinogenesis

(2009) ATHANASIOS VALAVANIDIS et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS

Inhibition of osteoblastic bone formation by nuclear factor-κB

(2009) Jia Chang et al.   NATURE MEDICINE

Ethanol extract ofFructus Ligustri Lucidipromotes osteogenesis of mesenchymal stem cells

(2009) Guo Li et al.   PHYTOTHERAPY RESEARCH

Fructus ligustri lucidi extract improves calcium balance and modulates the calciotropic hormone level and vitamin D-dependent gene expression in aged ovariectomized rats

(2008) Yan Zhang et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY