The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells

The Small Rho GTPase TC10 Modulates B Cell Immune Responses

(2017) Marianne Burbage et al.   JOURNAL OF IMMUNOLOGY

Paxillin regulates cell polarization and anterograde vesicle trafficking during cell migration

(2017) Fatemeh Dubois et al.   MOLECULAR BIOLOGY OF THE CELL

Vamp-7–dependent secretion at the immune synapse regulates antigen extraction and presentation in B-lymphocytes

(2017) Dorian Obino et al.   MOLECULAR BIOLOGY OF THE CELL

Polarized Exocytosis

(2017) Jingwen Zeng et al.   Cold Spring Harbor Perspectives in Biology

Regulation of Cell Polarity by Exocyst-Mediated Trafficking

(2017) Noemi Polgar et al.   Cold Spring Harbor Perspectives in Biology

Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion

(2017) Peng Yue et al.   Nature Communications

The Par3 polarity protein is an exocyst receptor essential for mammary cell survival

(2017) Syed Mukhtar Ahmed et al.   Nature Communications

The role of Exo70 in vascular smooth muscle cell migration

(2016) Wenqing Ma et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

GEF-H1 is necessary for neutrophil shear stress–induced migration during inflammation

(2016) Noah Fine et al.   JOURNAL OF CELL BIOLOGY

Antigen Presentation to B Cells

(2016) Balthasar A. Heesters et al.   TRENDS IN IMMUNOLOGY

Actin nucleation at the centrosome controls lymphocyte polarity

(2016) Dorian Obino et al.   Nature Communications

The Exocyst at a Glance

(2015) B. Wu et al.   JOURNAL OF CELL SCIENCE

Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse

(2015) Anne Reversat et al.   MOLECULAR BIOLOGY OF THE CELL

Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

(2015) Margaret R Heider et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex

(2015) Margaret R Heider et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Microtubule acetylation regulates dynamics of KIF1C-powered vesicles and contact of microtubule plus ends with podosomes

(2014) Ridhirama Bhuwania et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells

(2014) Ana M. Avalos et al.   Frontiers in Immunology

The Actin and Tetraspanin Networks Organize Receptor Nanoclusters to Regulate B Cell Receptor-Mediated Signaling

(2013) Pieta K. Mattila et al.   IMMUNITY

Cdc42 interacts with the exocyst complex to promote phagocytosis

(2013) Sina Mohammadi et al.   JOURNAL OF CELL BIOLOGY

The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p

(2013) David Shen et al.   JOURNAL OF CELL BIOLOGY

VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites

(2013) Paola Larghi et al.   NATURE IMMUNOLOGY

GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses

(2013) Hao-Sen Chiang et al.   NATURE IMMUNOLOGY

GTP Hydrolysis of TC10 Promotes Neurite Outgrowth through Exocytic Fusion of Rab11- and L1-Containing Vesicles by Releasing Exocyst Component Exo70

(2013) Akane Fujita et al.   PLoS One

B Cells Use Mechanical Energy to Discriminate Antigen Affinities

(2013) E. Natkanski et al.   SCIENCE

Exo70 Stimulates the Arp2/3 Complex for Lamellipodia Formation and Directional Cell Migration

(2012) Jianglan Liu et al.   CURRENT BIOLOGY

Phosphoinositide Signaling Regulates the Exocyst Complex and Polarized Integrin Trafficking in Directionally Migrating Cells

(2012) Narendra Thapa et al.   DEVELOPMENTAL CELL

The Microtubule-Associated Rho Activating Factor GEF-H1 Interacts with Exocyst Complex to Regulate Vesicle Traffic

(2012) Ritu Pathak et al.   DEVELOPMENTAL CELL

Exocyst complex component Sec8: a presumed component in the progression of human oral squamous-cell carcinoma by secretion of matrix metalloproteinases

(2012) Ayumi Yamamoto et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Microtubules regulate GEF-H1 in response to extracellular matrix stiffness

(2012) Jessica N. Heck et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanistic Insight into the Microtubule and Actin Cytoskeleton Coupling through Dynein-Dependent RhoGEF Inhibition

(2012) David Meiri et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fission Yeast Sec3 and Exo70 Are Transported on Actin Cables and Localize the Exocyst Complex to Cell Poles

(2012) Felipe O. Bendezú et al.   PLoS One

Exorcising the Exocyst Complex

(2012) Margaret R. Heider et al.   TRAFFIC

RalB and the Exocyst Mediate the Cellular Starvation Response by Direct Activation of Autophagosome Assembly

(2011) Brian O. Bodemann et al.   CELL

Polarized Secretion of Lysosomes at the B Cell Synapse Couples Antigen Extraction to Processing and Presentation

(2011) Maria-Isabel Yuseff et al.   IMMUNITY

Ral GTPases Regulate Cell-Mediated Cytotoxicity in NK Cells

(2011) J. Sanchez-Ruiz et al.   JOURNAL OF IMMUNOLOGY

Regulation of exocytosis by the exocyst subunit Sec6 and the SM protein Sec1

(2011) Francesca Morgera et al.   MOLECULAR BIOLOGY OF THE CELL

Golgi Bypass: Skirting Around the Heart of Classical Secretion

(2011) A. G. Grieve et al.   Cold Spring Harbor Perspectives in Biology

Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability

(2010) Anna A. Birukova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The Membrane Skeleton Controls Diffusion Dynamics and Signaling through the B Cell Receptor

(2010) Bebhinn Treanor et al.   IMMUNITY

Structure-Function Study of the N-terminal Domain of Exocyst Subunit Sec3

(2010) Kyuwon Baek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The exocyst complex in polarized exocytosis

(2009) Bing He et al.   CURRENT OPINION IN CELL BIOLOGY

The Strength of T Cell Receptor Signal Controls the Polarization of Cytotoxic Machinery to the Immunological Synapse

(2009) Misty R. Jenkins et al.   IMMUNITY

GEF-H1 Mediates Tumor Necrosis Factor-α-induced Rho Activation and Myosin Phosphorylation

(2009) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The TC10-Exo70 Complex Is Essential for Membrane Expansion and Axonal Specification in Developing Neurons

(2009) S. Dupraz et al.   JOURNAL OF NEUROSCIENCE

The Role of the Exocyst in Matrix Metalloproteinase Secretion and Actin Dynamics during Tumor Cell Invadopodia Formation

(2009) Jianglan Liu et al.   MOLECULAR BIOLOGY OF THE CELL

ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA

(2008) Shuh-hei Fujishiro et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Rap GTPases Regulate B Cell Morphology, Immune-Synapse Formation, and Signaling by Particulate B Cell Receptor Ligands

(2008) Kevin B.L. Lin et al.   IMMUNITY

Membrane association and functional regulation of Sec3 by phospholipids and Cdc42

(2008) Xiaoyu Zhang et al.   JOURNAL OF CELL BIOLOGY

Ral-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migration

(2008) K. S. Spiczka et al.   JOURNAL OF CELL SCIENCE

Cellular functions of GEF-H1, a microtubule-regulated Rho-GEF: is altered GEF-H1 activity a crucial determinant of disease pathogenesis?

(2008) Jörg Birkenfeld et al.   TRENDS IN CELL BIOLOGY