VAMP7 controls T cell activation by regulating the recruitment and phosphorylation of vesicular Lat at TCR-activation sites

How SNARE molecules mediate membrane fusion: Recent insights from molecular simulations

(2012) Herre Jelger Risselada et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

A Molecular Network for the Transport of the TI-VAMP/VAMP7 Vesicles from Cell Center to Periphery

(2012) Andrea Burgo et al.   DEVELOPMENTAL CELL

End-binding protein 1 controls signal propagation from the T cell receptor

(2012) Noa B Martín-Cófreces et al.   EMBO JOURNAL

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

(2012) Alexander Babich et al.   JOURNAL OF CELL BIOLOGY

Cytokine Secretion by CD4+ T Cells at the Immunological Synapse Requires Cdc42-Dependent Local Actin Remodeling but Not Microtubule Organizing Center Polarity

(2012) K. Chemin et al.   JOURNAL OF IMMUNOLOGY

Absence of TI-VAMP/Vamp7 Leads to Increased Anxiety in Mice

(2012) L. Danglot et al.   JOURNAL OF NEUROSCIENCE

Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes

(2011) R Alonso et al.   CELL DEATH AND DIFFERENTIATION

Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

(2011) Eilon Sherman et al.   IMMUNITY

MAL Protein Controls Protein Sorting at the Supramolecular Activation Cluster of Human T Lymphocytes

(2011) O. M. Anton et al.   JOURNAL OF IMMUNOLOGY

Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments

(2011) Akanksha Chaturvedi et al.   NATURE IMMUNOLOGY

Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events

(2011) David J Williamson et al.   NATURE IMMUNOLOGY

Force Generation upon T Cell Receptor Engagement

(2011) Julien Husson et al.   PLoS One

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

(2011) Gregory D. Rak et al.   PLOS BIOLOGY

Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

(2011) Alice C. N. Brown et al.   PLOS BIOLOGY

Essential Role of Ubiquitin and TSG101 Protein in Formation and Function of the Central Supramolecular Activation Cluster

(2010) Santosha Vardhana et al.   IMMUNITY

PALM imaging and cluster analysis of protein heterogeneity at the cell surface

(2010) Dylan M. Owen et al.   Journal of Biophotonics

Role of TI-VAMP and CD82 in EGFR cell-surface dynamics and signaling

(2010) L. Danglot et al.   JOURNAL OF CELL SCIENCE

Dynamics of Subsynaptic Vesicles and Surface Microclusters at the Immunological Synapse

(2010) M. A. Purbhoo et al.   Science Signaling

Lymphoproliferative disorders involving T helper effector cells with defective LAT signalosomes

(2010) Romain Roncagalli et al.   Seminars in Immunopathology

Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking

(2009) Mathilde Chaineau et al.   FEBS LETTERS

Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor

(2009) Michael Mingueneau et al.   IMMUNITY

TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation

(2009) Björn F Lillemeier et al.   NATURE IMMUNOLOGY

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

(2008) Leif E. Sander et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line

(2007) Marcelo Marcet-Palacios et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS