Direct observation of branching MT nucleation in living animal cells

Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth

(2019) Ana F. David et al.   JOURNAL OF CELL BIOLOGY

The PSIPRED Protein Analysis Workbench: 20 years on

(2019) Daniel W A Buchan et al.   NUCLEIC ACIDS RESEARCH

Microtubule plus-ends act as physical signaling hubs to activate RhoA during cytokinesis

(2019) Vikash Verma et al.   eLife

Spatiotemporal organization of branched microtubule networks

(2019) Akanksha Thawani et al.   eLife

Augmin Antagonizes Katanin at Microtubule Crossovers to Control the Dynamic Organization of Plant Cortical Arrays

(2018) Guangda Wang et al.   CURRENT BIOLOGY

Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules

(2018) Jae-Geun Song et al.   JOURNAL OF CELL BIOLOGY

TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis

(2018) Sriyash Mangal et al.   JOURNAL OF CELL BIOLOGY

Measuring and modeling polymer concentration profiles near spindle boundaries argues that spindle microtubules regulate their own nucleation

(2018) Bryan Kaye et al.   NEW JOURNAL OF PHYSICS

Autocatalytic microtubule nucleation determines the size and mass of Xenopus laevis egg extract spindles

(2018) Franziska Decker et al.   eLife

Direct induction of microtubule branching by microtubule nucleation factor SSNA1

(2018) Nirakar Basnet et al.   NATURE CELL BIOLOGY

Microtubule nucleation by γ-tubulin complexes and beyond

(2018) Corinne A. Tovey et al.   Essays in Biochemistry

Structural analysis of the role of TPX2 in branching microtubule nucleation

(2017) Raymundo Alfaro-Aco et al.   JOURNAL OF CELL BIOLOGY

Microtubule nucleation: beyond the template

(2017) Johanna Roostalu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-tubulin ring complex to the mitotic spindle

(2017) Jack W. C. Chen et al.   Biology Open

Suppression of microtubule assembly kinetics by the mitotic protein TPX2

(2016) Taylor A. Reid et al.   JOURNAL OF CELL SCIENCE

Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission

(2016) Ryota Uehara et al.   MOLECULAR BIOLOGY OF THE CELL

Spatial organization of the Ran pathway by microtubules in mitosis

(2016) Doogie Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity

(2016) Carlos Sánchez-Huertas et al.   Nature Communications

Physical basis of large microtubule aster growth

(2016) Keisuke Ishihara et al.   eLife

TPX2

(2015) Pat Wadsworth   CURRENT BIOLOGY

Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway

(2015) Anna A. Ye et al.   CURRENT BIOLOGY

Spatial Regulation of Kinetochore Microtubule Attachments by Destabilization at Spindle Poles in Meiosis I

(2015) Lukáš Chmátal et al.   CURRENT BIOLOGY

Thirty years of search and capture: The complex simplicity of mitotic spindle assembly

(2015) Rebecca Heald et al.   JOURNAL OF CELL BIOLOGY

Augmin Triggers Microtubule-Dependent Microtubule Nucleation in Interphase Plant Cells

(2014) Ting Liu et al.   CURRENT BIOLOGY

GCP-WD Mediates γ-TuRC Recruitment and the Geometry of Microtubule Nucleation in Interphase Arrays of Arabidopsis

(2014) Ankit Walia et al.   CURRENT BIOLOGY

Synergy between Multiple Microtubule-Generating Pathways Confers Robustness to Centrosome-Driven Mitotic Spindle Formation

(2014) Daniel Hayward et al.   DEVELOPMENTAL CELL

Reconstitution of the augmin complex provides insights into its architecture and function

(2014) Kuo-Chiang Hsia et al.   NATURE CELL BIOLOGY

Microtubule nucleation remote from centrosomes may explain how asters span large cells

(2014) Keisuke Ishihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Branching Microtubule Nucleation in Xenopus Egg Extracts Mediated by Augmin and TPX2

(2013) Sabine Petry et al.   CELL

Ultrastructure of protrusive actin filament arrays

(2013) Tatyana M Svitkina   CURRENT OPINION IN CELL BIOLOGY

Augmin-dependent microtubule nucleation at microtubule walls in the spindle

(2013) Tomoko Kamasaki et al.   JOURNAL OF CELL BIOLOGY

Restarting life: fertilization and the transition from meiosis to mitosis

(2013) Dean Clift et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nucleation and Transport Organize Microtubules in Metaphase Spindles

(2012) Jan Brugués et al.   CELL

Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells

(2012) Timothy Mitchison et al.   Cytoskeleton

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Aurora-A Phosphorylates Augmin Complex Component Hice1 Protein at an N-terminal Serine/Threonine Cluster to Modulate Its Microtubule Binding Activity during Spindle Assembly

(2011) Connie Y. Tsai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a TPX2-Like Microtubule-Associated Protein in Drosophila

(2011) Gohta Goshima   PLoS One

Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1

(2011) Y. Johmura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase

(2010) Ryota Uehara et al.   JOURNAL OF CELL BIOLOGY

Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux

(2010) Nan Ma et al.   MOLECULAR BIOLOGY OF THE CELL

Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry

(2010) Justin M. Kollman et al.   NATURE

Microtubule and katanin-dependent dynamics of microtubule nucleation complexes in the acentrosomal Arabidopsis cortical array

(2010) Masayoshi Nakamura et al.   NATURE CELL BIOLOGY

Spindle Assembly in the Absence of a RanGTP Gradient Requires Localized CPC Activity

(2009) Thomas J. Maresca et al.   CURRENT BIOLOGY

HAUS, the 8-Subunit Human Augmin Complex, Regulates Centrosome and Spindle Integrity

(2009) Steffen Lawo et al.   CURRENT BIOLOGY

Wac: a new Augmin subunit required for chromosome alignment but not for acentrosomal microtubule assembly in female meiosis

(2009) Ana M. Meireles et al.   JOURNAL OF CELL BIOLOGY

Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the  TuRC to the centrosome

(2009) X. Zhang et al.   JOURNAL OF CELL SCIENCE

Functional Overlap of Microtubule Assembly Factors in Chromatin-Promoted Spindle Assembly

(2009) Aaron C. Groen et al.   MOLECULAR BIOLOGY OF THE CELL

Arabidopsis Cortical Microtubules Are Initiated along, as Well as Branching from, Existing Microtubules

(2009) J. Chan et al.   PLANT CELL

The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells

(2009) R. Uehara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for an Upper Limit to Mitotic Spindle Length

(2008) Martin Wühr et al.   CURRENT BIOLOGY

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

(2008) Gohta Goshima et al.   JOURNAL OF CELL BIOLOGY

FAM29A promotes microtubule amplification via recruitment of the NEDD1–γ-tubulin complex to the mitotic spindle

(2008) Hui Zhu et al.   JOURNAL OF CELL BIOLOGY

The RanGTP gradient - a GPS for the mitotic spindle

(2008) P. Kalab et al.   JOURNAL OF CELL SCIENCE

Hice1, a Novel Microtubule-Associated Protein Required for Maintenance of Spindle Integrity and Chromosomal Stability in Human Cells

(2008) G. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

The Plant TPX2 Protein Regulates Prospindle Assembly before Nuclear Envelope Breakdown

(2008) J. W. Vos et al.   PLANT CELL