Treatment with scFv-h3D6 Prevented Neuronal Loss and Improved Spatial Memory in Young 3xTg-AD Mice by Reducing the Intracellular Amyloid-β Burden

Peripheral complement interactions with amyloid β peptide in Alzheimer's disease: 2. Relationship to amyloid β immunotherapy

(2018) Andrés Crane et al.   Alzheimers & Dementia

AβPP Accumulation and/or Intraneuronal Amyloid-β Accumulation? The 3xTg-AD Mouse Model Revisited

(2018) Oliver Wirths et al.   JOURNAL OF ALZHEIMERS DISEASE

Autoimmune Manifestations in the 3xTg-AD Model of Alzheimer's Disease

(2018) Monica Marchese et al.   JOURNAL OF ALZHEIMERS DISEASE

An Intracellular Amyloid-β/AβPP Epitope Correlates with Neurodegeneration in those Neuronal Populations Early Involved in Alzheimer’s Disease

(2017) Gisela Esquerda-Canals et al.   JOURNAL OF ALZHEIMERS DISEASE

Mouse Models of Alzheimer’s Disease

(2017) Gisela Esquerda-Canals et al.   JOURNAL OF ALZHEIMERS DISEASE

Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes

(2017) Wei Qiang et al.   NATURE

Production of an anti-Aβ antibody fragment in Pichia pastoris and in vitro and in vivo validation of its therapeutic effect

(2017) Laia Montoliu-Gaya et al.   PLoS One

Alzheimer's disease: The amyloid hypothesis on trial

(2016) Judith R. Harrison et al.   BRITISH JOURNAL OF PSYCHIATRY

Intracellular A? and its Pathological Role in Alzheimer's Disease: Lessons from Cellular to Animal Models

(2016) Lina Ji et al.   Current Alzheimer Research

Aβ-Immunotherapeutic strategies: a wide range of approaches for Alzheimer's disease treatment

(2016) Laia Montoliu-Gaya et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Comparing the efficacy and neuroinflammatory potential of three anti-abeta antibodies

(2015) James P. Fuller et al.   ACTA NEUROPATHOLOGICA

Enfermedad de Alzheimer: nuevas estrategias terapéuticas

(2015) Sandra Villegas   MEDICINA CLINICA

Abundance of Aβ5-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer’s disease

(2014) Erika Guzmán et al.   Molecular Neurodegeneration

Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

(2014) Anna Pensalfini et al.   NEUROBIOLOGY OF DISEASE

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice

(2014) V Gatta et al.   Cell Death & Disease

New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease

(2014) James P. Fuller et al.   Frontiers in Neuroscience

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

An improved model for calculating CO2 solubility in aqueous NaCl solutions and the application to CO2–H2O–NaCl fluid inclusions

(2013) Shide Mao et al.   CHEMICAL GEOLOGY

Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

(2013) Suhail Rasool et al.   JOURNAL OF NEUROCHEMISTRY

Loss of deep cerebellar nuclei neurons in the 3xTg-AD mice and protection by an anti-amyloid β antibody fragment

(2013) Gisela Esquerda-Canals et al.   mAbs

Early intervention in the 3xTg-AD mice with an amyloid β-antibody fragment ameliorates first hallmarks of Alzheimer disease

(2013) Lydia Giménez-Llort et al.   mAbs

Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

(2013) William A Eimer et al.   Molecular Neurodegeneration

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

(2012) Katherine L Youmans et al.   Molecular Neurodegeneration

An anti-Aβ (amyloid β) single-chain variable fragment prevents amyloid fibril formation and cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway

(2011) Marta Marín-Argany et al.   BIOCHEMICAL JOURNAL

Neurogenesis in Alzheimer’s disease

(2011) José J. Rodríguez et al.   JOURNAL OF ANATOMY

Intraneuronal APP, Not Free A  Peptides in 3xTg-AD Mice: Implications for Tau versus A -Mediated Alzheimer Neurodegeneration

(2011) M. J. Winton et al.   JOURNAL OF NEUROSCIENCE

Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

(2010) Gunnar K. Gouras et al.   ACTA NEUROPATHOLOGICA

Sex differences in β-amyloid accumulation in 3xTg-AD mice: Role of neonatal sex steroid hormone exposure

(2010) Jenna C. Carroll et al.   BRAIN RESEARCH

Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer’s disease

(2010) Laura K. Hamilton et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Transgenic Mouse Models of Alzheimer's Disease

(2010) Gregory A. Elder et al.   MOUNT SINAI JOURNAL OF MEDICINE

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Intraneuronal β-Amyloid Accumulation in the Amygdala Enhances Fear and Anxiety in Alzheimer's Disease Transgenic Mice

(2009) Judit España et al.   BIOLOGICAL PSYCHIATRY

Targeting BuChE-inflammatory Pathway by SK0506 to Manage Type 2 Diabetes and Alzheimer Disease

(2009) M. A. Kamal et al.   NEUROCHEMICAL RESEARCH

Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice

(2008) Michelle C. Janelsins et al.   AMERICAN JOURNAL OF PATHOLOGY

Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice

(2008) Michael A Mastrangelo et al.   BMC NEUROSCIENCE