GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS
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Title
GDF15 mediates adiposity resistance through actions on GFRAL neurons in the hindbrain AP/NTS
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF OBESITY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-06-01
DOI
10.1038/s41366-019-0365-5
References
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Related references
Note: Only part of the references are listed.- Uniting GDF15 and GFRAL: Therapeutic Opportunities in Obesity and Beyond
- (2018) Shannon E. Mullican et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The MIC-1/GDF15-GFRAL Pathway in Energy Homeostasis: Implications for Obesity, Cachexia, and Other Associated Diseases
- (2018) Vicky W.W. Tsai et al. Cell Metabolism
- Genetic identification of leptin neural circuits in energy and glucose homeostases
- (2018) Jie Xu et al. NATURE
- Treatment with the TGF-b superfamily cytokine MIC-1/GDF15 reduces the adiposity and corrects the metabolic dysfunction of mice with diet-induced obesity
- (2017) V W Tsai et al. INTERNATIONAL JOURNAL OF OBESITY
- Non-homeostatic body weight regulation through a brainstem-restricted receptor for GDF15
- (2017) Jer-Yuan Hsu et al. NATURE
- GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand
- (2017) Linda Yang et al. NATURE MEDICINE
- GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates
- (2017) Shannon E Mullican et al. NATURE MEDICINE
- The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL
- (2017) Paul J Emmerson et al. NATURE MEDICINE
- Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys
- (2017) Yumei Xiong et al. Science Translational Medicine
- Targeting Obesity and Cachexia: Identification of the GFRAL Receptor–MIC-1/GDF15 Pathway
- (2017) Samuel N. Breit et al. TRENDS IN MOLECULAR MEDICINE
- Anorexia–cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15
- (2015) V W W Tsai et al. INTERNATIONAL JOURNAL OF OBESITY
- MAP3K11/GDF15 axis is a critical driver of cancer cachexia
- (2015) Lorena Lerner et al. Journal of Cachexia Sarcopenia and Muscle
- Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI
- (2015) Vicky Wang-Wei Tsai et al. PLoS One
- The Anorectic Actions of the TGFβ Cytokine MIC-1/GDF15 Require an Intact Brainstem Area Postrema and Nucleus of the Solitary Tract
- (2014) Vicky Wang-Wei Tsai et al. PLoS One
- TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator
- (2013) Vicky Wang-Wei Tsai et al. PLoS One
- Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets
- (2012) Laurence Macia et al. PLoS One
- Identification of Body Fat Mass as a Major Determinant of Metabolic Rate in Mice
- (2010) K. J. Kaiyala et al. DIABETES
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