Long Non-Coding RNAs in Kidney Disease

microRNAs in chronic kidney disease

(2019) Hui Zhao et al.   CLINICA CHIMICA ACTA

MicroRNAs in Acute Kidney Injury and Kidney Transplantation

(2019) Kristien J. Ledeganck et al.   Clinical Journal of the American Society of Nephrology

Long noncoding RNA LINC00339 promotes renal tubular epithelial pyroptosis by regulating the miR-22-3p/NLRP3 axis in calcium oxalate-induced kidney stone

(2019) Zhengyao Song et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

LncRNA TapSAKI promotes inflammation injury in HK-2 cells and urine derived sepsis-induced kidney injury

(2019) Jun Shen et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Upregulated long noncoding RNA LOC105375913 induces tubulointerstitial fibrosis in focal segmental glomerulosclerosis

(2019) Runhong Han et al.   Scientific Reports

Single-Cell RNA Profiling of Glomerular Cells Shows Dynamic Changes in Experimental Diabetic Kidney Disease

(2019) Jia Fu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A negative feedback loop of H19/miR-675/EGR1 is involved in diabetic nephropathy by downregulating the expression of the vitamin D receptor

(2019) WenXing Fan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Deregulation of long noncoding RNA (TUG1) contributes to excessive podocytes apoptosis by activating endoplasmic reticulum stress in the development of diabetic nephropathy

(2019) Hongchun Shen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LINC00520 targeting miR-27b-3p regulates OSMR expression level to promote acute kidney injury development through the PI3K/AKT signaling pathway

(2019) Xinghan Tian et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Downregulation of lncRNA TUG1 contributes to the development of sepsis-associated acute kidney injury via regulating miR-142-3p/sirtuin 1 axis and modulating NF-κB pathway

(2019) Xiaodi Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inhibition of lncRNA MEG3 protects renal tubular from hypoxia-induced kidney injury in acute renal allografts by regulating miR-181b/TNF-α signaling pathway

(2019) Xinlu Pang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Long noncoding RNA MALAT1 mediates high glucose-induced glomerular endothelial cell injury by epigenetically inhibiting klotho via methyltransferase G9a

(2019) Yebei Li et al.   IUBMB LIFE

LRNA9884, a Novel Smad3-Dependent LncRNA, Promotes Diabetic Kidney Injury in db/db Mice Via Enhancing MCP-1-Dependent Renal Inflammation

(2019) Ying-ying Zhang et al.   DIABETES

Non-Coding RNAs as New Therapeutic Targets in the Context of Renal Fibrosis

(2019) Cynthia Van der Hauwaert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cellular functions of long noncoding RNAs

(2019) Run-Wen Yao et al.   NATURE CELL BIOLOGY

LncRNA NEAT1 promotes hypoxia‐induced renal tubular epithelial apoptosis through downregulating miR‐27a‐3p

(2019) Xinxin Jiang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Identification of Renal Long Non-coding RNA RP11-2B6.2 as a Positive Regulator of Type I Interferon Signaling Pathway in Lupus Nephritis

(2019) Zhuojun Liao et al.   Frontiers in Immunology

Long Noncoding RNA LINC01619 Regulates MicroRNA-27a/Forkhead Box Protein O1 and Endoplasmic Reticulum Stress-Mediated Podocyte Injury in Diabetic Nephropathy

(2018) Xiaoyan Bai et al.   ANTIOXIDANTS & REDOX SIGNALING

LncRNA Uc.173 is a key molecule for the regulation of lead-induced renal tubular epithelial cell apoptosis

(2018) Jiabi Qin et al.   BIOMEDICINE & PHARMACOTHERAPY

Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223

(2018) Yan Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

Effects of Long Non-Coding RNA LINC00963 on Renal Interstitial Fibrosis and Oxidative Stress of Rats with Chronic Renal Failure via the Foxo Signaling Pathway

(2018) Wen Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Potential role of lncRNAs in contributing to pathogenesis of chronic glomerulonephritis based on microarray data

(2018) Jia-rong Gao et al.   GENE

Long non-coding RNA NEAT1 plays an important role in sepsis-induced acute kidney injury by targeting miR-204 and modulating the NF-κB pathway

(2018) Yi Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Long noncoding RNAHoxb3osis dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling

(2018) Karam Aboudehen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of maternally expressed gene 3 attenuated lipopolysaccharide-induced apoptosis through sponging miR-21 in renal tubular epithelial cells

(2018) Ru Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A Single-Cell Transcriptome Atlas of the Mouse Glomerulus

(2018) Nikos Karaiskos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

(2018) David Adams et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis

(2018) Merrill D. Benson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling

(2018) Ailing Li et al.   Cell Death & Disease

Hypoxia-induced long non-coding RNA Malat1 is dispensable for renal ischemia/reperfusion-injury

(2018) Malte Kölling et al.   Scientific Reports

Analyses of long non-coding RNA and mRNA profiling using RNA sequencing in calcium oxalate monohydrate-stimulated renal tubular epithelial cells

(2018) Zhu Wang et al.   Urolithiasis

Changing expression profiles of long non-coding RNAs, mRNAs and circular RNAs in ethylene glycol-induced kidney calculi rats

(2018) Yanan Cao et al.   BMC GENOMICS

Long Non-Coding RNA CYP4B1-PS1-001 Inhibits Proliferation and Fibrosis in Diabetic Nephropathy by Interacting with Nucleolin

(2018) Suyu Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

LncRNA HOX transcript antisense RNA accelerated kidney injury induced by urine-derived sepsis through the miR-22/high mobility group box 1 pathway

(2018) Jun Shen et al.   LIFE SCIENCES

The effect of long noncoding RNA GAS5 on apoptosis in renal ischemia/reperfusion injury

(2018) Xuemei Geng et al.   NEPHROLOGY

Astragaloside IV/lncRNA-TUG1/TRAF5 signaling pathway participates in podocyte apoptosis of diabetic nephropathy rats

(2018) Xiao Lei et al.   Drug Design Development and Therapy

lncRNA ZEB1-AS1 Was Suppressed by p53 for Renal Fibrosis in Diabetic Nephropathy

(2018) Juan Wang et al.   Molecular Therapy-Nucleic Acids

Down‐regulation of the long non‐coding RNA XIST ameliorates podocyte apoptosis in membranous nephropathy via the miR‐217–TLR4 pathway

(2018) Ling‐wei Jin et al.   EXPERIMENTAL PHYSIOLOGY

The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosis

(2018) Shuai Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long noncoding RNA NEAT1 accelerates the proliferation and fibrosis in diabetic nephropathy through activating Akt/mTOR signaling pathway

(2018) Shan Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

EA15, MIR22, LINC00472 as diagnostic markers for diabetic kidney disease

(2018) Yan-Zhe Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Long noncoding RNA Gm6135 functions as a competitive endogenous RNA to regulate toll-like receptor 4 expression by sponging miR-203-3p in diabetic nephropathy

(2018) Ting-Ting Ji et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LncRNA NEAT1 promotes extracellular matrix accumulation and epithelial‐to‐mesenchymal transition by targeting miR‐27b‐3p and ZEB1 in diabetic nephropathy

(2018) Xiaowei Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Advantages of Single-Nucleus over Single-Cell RNA Sequencing of Adult Kidney: Rare Cell Types and Novel Cell States Revealed in Fibrosis

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The long non-coding RNA MALAT1 is increased in renal ischemia-reperfusion injury and inhibits hypoxia-induced inflammation

(2018) Hongyan Tian et al.   RENAL FAILURE

LncRNAs expression in adriamycin-induced rats reveals the potential role of LncRNAs contributing to chronic glomerulonephritis pathogenesis

(2018) Xiu-juan Qin et al.   GENE

Effects of long non-coding RNA LINC00667 on renal tubular epithelial cell proliferation, apoptosis and renal fibrosis via the miR-19b-3p/LINC00667/CTGF signaling pathway in chronic renal failure

(2018) Wen Chen et al.   CELLULAR SIGNALLING

LncRNA ANRIL promotes NLRP3 inflammasome activation in uric acid nephropathy through miR-122-5p/BRCC3 axis

(2018) Jiacai Hu et al.   BIOCHIMIE

Long noncoding RNA MALAT1 regulates renal tubular epithelial pyroptosis by modulated miR-23c targeting of ELAVL1 in diabetic nephropathy

(2017) Xue Li et al.   EXPERIMENTAL CELL RESEARCH

Long non-coding RNA PVT1 promote LPS-induced septic acute kidney injury by regulating TNFα and JNK/NF-κB pathways in HK-2 cells

(2017) Wei Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mechanism of long non-coding RNA MALAT1 in lipopolysaccharide-induced acute kidney injury is mediated by the miR-146a/NF-κB signaling pathway

(2017) Ying Ding et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

LncRNA MALAT1 is dysregulated in diabetic nephropathy and involved in high glucose-induced podocyte injury via its interplay with β-catenin

(2017) Mengsi Hu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Differentially expressed long non-coding RNAs and mRNAs in patients with IgA nephropathy

(2017) Nan Zuo et al.   Molecular Medicine Reports

LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy

(2017) Hong Yi et al.   Cell Death & Disease

RNA-sequencing reveals genome-wide long non-coding RNAs profiling associated with early development of diabetic nephropathy

(2017) Wanxin Tang et al.   Oncotarget

The specificity of long noncoding RNA expression

(2016) Brian S. Gloss et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy

(2016) Jianyin Long et al.   JOURNAL OF CLINICAL INVESTIGATION

A novel long non-coding RNA CYP4B1-PS1-001 regulates proliferation and fibrosis in diabetic nephropathy

(2016) Min Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Unique features of long non-coding RNA biogenesis and function

(2016) Jeffrey J. Quinn et al.   NATURE REVIEWS GENETICS

An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy

(2016) Mitsuo Kato et al.   Nature Communications

RANTES mediates kidney ischemia reperfusion injury through a possible role of HIF-1α and LncRNA PRINS

(2016) Tung-Min Yu et al.   Scientific Reports

Diabetes

(2015) David M. Nathan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Long non-coding RNA MALAT1 regulates hyperglycaemia induced inflammatory process in the endothelial cells

(2015) Prasanth Puthanveetil et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology

(2015) Ravindra L Mehta et al.   LANCET

The Landscape of long noncoding RNA classification

(2015) Georges St. Laurent et al.   TRENDS IN GENETICS

A transcribed ultraconserved noncoding RNA, Uc.173, is a key molecule for the inhibition of lead-induced neuronal apoptosis

(2015) Aruo Nan et al.   Oncotarget

Urinary Xist is a potential biomarker for membranous nephropathy

(2014) Yen-Sung Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Circulating Long Noncoding RNA TapSAKI Is a Predictor of Mortality in Critically Ill Patients with Acute Kidney Injury

(2014) J. M. Lorenzen et al.   CLINICAL CHEMISTRY

Long non-coding RNA in health and disease

(2014) Philipp G. Maass et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Evolutionary conservation of long non-coding RNAs; sequence, structure, function

(2013) Per Johnsson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy?

(2013) G C Higgins et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diabetic nephropathy: diagnosis and treatment

(2013) Daniel Fineberg et al.   Nature Reviews Endocrinology

Role of MicroRNA 1207-5P and Its Host Gene, the Long Non-Coding RNA Pvt1, as Mediators of Extracellular Matrix Accumulation in the Kidney: Implications for Diabetic Nephropathy

(2013) M. Lucrecia Alvarez et al.   PLoS One

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Altered long non-coding RNA expression profile in patients with IgA-negative mesangial proliferative glomerulonephritis

(2012) Yong Dai   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Functional Characterization of the Plasmacytoma Variant Translocation 1 Gene (PVT1) in Diabetic Nephropathy

(2011) M. Lucrecia Alvarez et al.   PLoS One

The Identification of MicroRNAs in a Genomically Unstable Region of Human Chromosome 8q24

(2008) K. Huppi et al.   MOLECULAR CANCER RESEARCH