An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

A Bayesian framework for multiple trait colocalization from summary association statistics

(2018) Claudia Giambartolomei et al.   BIOINFORMATICS

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease

(2018) Tom G Richardson et al.   HUMAN MOLECULAR GENETICS

Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood

(2018) Ting Qi et al.   Nature Communications

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

(2018) Elmar W. Tobi et al.   Science Advances

A critical view on transgenerational epigenetic inheritance in humans

(2018) Bernhard Horsthemke   Nature Communications

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

(2017) Gemma C Sharp et al.   HUMAN MOLECULAR GENETICS

An epigenome-wide association study meta-analysis of educational attainment

(2017) R Karlsson Linnér et al.   MOLECULAR PSYCHIATRY

Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease

(2017) Barbara E Stranger et al.   NATURE GENETICS

Epigenome-wide association study of chronic obstructive pulmonary disease and lung function in Koreans

(2017) Mi Kyeong Lee et al.   Epigenomics

DNA methylation signatures in peripheral blood strongly predict all-cause mortality

(2017) Yan Zhang et al.   Nature Communications

Understanding Tissue-Specific Gene Regulation

(2017) Abhijeet Rajendra Sonawane et al.   Cell Reports

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

(2016) Bonnie R. Joubert et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Epigenetic Signatures of Cigarette SmokingCLINICAL PERSPECTIVE

(2016) Roby Joehanes et al.   Circulation-Cardiovascular Genetics

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Maternal Rest/Nrsf Regulates Zebrafish Behavior through snap25a/b

(2016) Cara E. Moravec et al.   JOURNAL OF NEUROSCIENCE

Epigenome-wide association study of body mass index and the adverse outcomes of adiposity

(2016) Simone Wahl et al.   NATURE

Disease variants alter transcription factor levels and methylation of their binding sites

(2016) Marc Jan Bonder et al.   NATURE GENETICS

Epigenetic modulators, modifiers and mediators in cancer aetiology and progression

(2016) Andrew P. Feinberg et al.   NATURE REVIEWS GENETICS

Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns

(2016) Bonnie R. Joubert et al.   Nature Communications

Epigenetic Signatures of Cigarette SmokingCLINICAL PERSPECTIVE

(2016) Roby Joehanes et al.   Circulation-Cardiovascular Genetics

Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation

(2016) Saskia Trump et al.   Scientific Reports

REST is a hypoxia-responsive transcriptional repressor

(2016) Miguel A. S. Cavadas et al.   Scientific Reports

The Genotype-Tissue Expression (GTEx) Project

(2015) Latarsha J. Carithers et al.   BIOPRESERVATION AND BIOBANKING

Data Resource Profile: Accessible Resource for Integrated Epigenomic Studies (ARIES)

(2015) Caroline L Relton et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian randomization: applications and limitations in epigenetic studies

(2015) Caroline L Relton et al.   Epigenomics

The Genotype-Tissue Expression (GTEx) Project

(2015) Latarsha J. Carithers et al.   Biopreservation and Biobanking

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Prenatal exposure to maternal smoking and offspring DNA methylation across the lifecourse: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)

(2015) Rebecca C. Richmond et al.   HUMAN MOLECULAR GENETICS

Approaches for drawing causal inferences from epidemiological birth cohorts: A review

(2014) Rebecca C. Richmond et al.   EARLY HUMAN DEVELOPMENT

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

(2013) Elin Grundberg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data

(2013) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Calculating statistical power in Mendelian randomization studies

(2013) Marie-Jo A Brion et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Molecular cytogenetic analysis for TFE3 rearrangement in Xp11.2 renal cell carcinoma and alveolar soft part sarcoma: validation and clinical experience with 75 cases

(2013) Jennelle C Hodge et al.   MODERN PATHOLOGY

LRRC45 Is a Centrosome Linker Component Required for Centrosome Cohesion

(2013) Runsheng He et al.   Cell Reports

Cigarette smoking and DNA methylation

(2013) Ken W. K. Lee et al.   Frontiers in Genetics

Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort

(2012) A. Fraser et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

(2012) Andy Boyd et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Two-step epigenetic Mendelian randomization: a strategy for establishing the causal role of epigenetic processes in pathways to disease

(2012) Caroline L Relton et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia

(2012) Marta Kulis et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

(2012) Jordana T. Bell et al.   PLoS Genetics

Epigenetic Modifications

(2011) Diane E. Handy et al.   CIRCULATION

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

The Effects of Smoking on the Developing Lung: Insights from a Biologic Model for Lung Development, Homeostasis, and Repair

(2009) Virender K. Rehan et al.   LUNG