Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis via regulation of ROS/NLRP3/Caspase-1 signaling pathway

USCAP 2018 Abstracts: Autopsy (1–44)

(2018)   LABORATORY INVESTIGATION

Pharmacological benefits of neferine - A comprehensive review

(2018) Shibu Marthandam Asokan et al.   LIFE SCIENCES

Caspase-11-mediated tubular epithelial pyroptosis underlies contrast-induced acute kidney injury

(2018) Zhen Zhang et al.   Cell Death & Disease

Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation

(2017) Shaofei Wang et al.   Cell Death & Disease

Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells

(2017) Onat Kadioglu et al.   Frontiers in Pharmacology

The NLRP3 inflammasome in kidney disease and autoimmunity

(2016) Holly L Hutton et al.   NEPHROLOGY

Targeting Cell Death Pathways for Therapeutic Intervention in Kidney Diseases

(2016) Jay P. Garg et al.   SEMINARS IN NEPHROLOGY

Cadmium induces NLRP3 inflammasome-dependent pyroptosis in vascular endothelial cells

(2016) Haiyan Chen et al.   TOXICOLOGY LETTERS

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

(2015) Justine M. Abais et al.   ANTIOXIDANTS & REDOX SIGNALING

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

An update on the role of the inflammasomes in the pathogenesis of kidney diseases

(2015) Murthy N. Darisipudi et al.   PEDIATRIC NEPHROLOGY

NLRP3 Inflammasome Activation in Dialyzed Chronic Kidney Disease Patients

(2015) Simona Granata et al.   PLoS One

NLRP3 Inflammasome as a Novel Player in Myocardial Infarction

(2014) Masafumi Takahashi   International Heart Journal

Targeting inflammation: New therapeutic approaches in chronic kidney disease (CKD)

(2014) Daniela Impellizzeri et al.   PHARMACOLOGICAL RESEARCH

Oxidative stress in patients with cardiovascular disease and chronic renal failure

(2013) A. Popolo et al.   FREE RADICAL RESEARCH

Neferine isolated from Nelumbo nucifera enhances anti-cancer activities in Hep3B cells: Molecular mechanisms of cell cycle arrest, ER stress induced apoptosis and anti-angiogenic response

(2013) Jin-Soo Yoon et al.   PHYTOMEDICINE

Protective Effect of Neferine Against Isoproterenol-Induced Cardiac Toxicity

(2012) Gurusamy Lalitha et al.   Cardiovascular Toxicology

Impact of sevelamer versus calcium-based binders on hospitalizations and missed in-center dialysis treatments among CKD patients on dialysis: a modeled analysis

(2012) Daniel T. Grima et al.   CURRENT MEDICAL RESEARCH AND OPINION

Neferine Inhibits the Upregulation of CCL5 and CCR5 in Vascular Endothelial Cells During Chronic High Glucose Treatment

(2012) Guilin Li et al.   INFLAMMATION

Neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 MAPK-mediated p21 stabilization

(2011) Xiyu Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Chronic kidney disease

(2011) Andrew S Levey et al.   LANCET

NLRP3 inflammasomes link inflammation and metabolic disease

(2011) Dominic De Nardo et al.   TRENDS IN IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis

(2009) Libo Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neferine enhances insulin sensitivity in insulin resistant rats

(2009) Yang Pan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Reply: Vitamin D compounds in chronic kidney disease: change may be needed for good!

(2008) S. Palmer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION