Integrate genome-based assessment of safety for probiotic strains: Bacillus coagulans GBI-30, 6086 as a case study

Novel probiotics and prebiotics: road to the market

(2015) Himanshu Kumar et al.   CURRENT OPINION IN BIOTECHNOLOGY

Complete genome sequence of Bifidobacterium adolesentis BBMN23, a probiotic strain from healthy centenarian

(2015) Songling Liu et al.   JOURNAL OF BIOTECHNOLOGY

Complete genome sequence of Bifidobacterium animalis subsp. lactis A6, a probiotic strain with high acid resistance ability

(2015) Erna Sun et al.   JOURNAL OF BIOTECHNOLOGY

Bacillus coagulans GBI-30, 6086 Modulates Faecalibacterium prausnitzii in Older Men and Women

(2015) Edna P Nyangale et al.   JOURNAL OF NUTRITION

Feasibility of Genome-Wide Screening for Biosafety Assessment of Probiotics: A Case Study of Lactobacillus helveticus MTCC 5463

(2015) S. Senan et al.   Probiotics and Antimicrobial Proteins

Effect of prebiotics on the fecal microbiota of elderly volunteers after dietary supplementation of Bacillus coagulans GBI-30, 6086

(2014) Edna P. Nyangale et al.   ANAEROBE

Effects of genetic, processing, or product formulation changes on efficacy and safety of probiotics

(2014) Mary Ellen Sanders et al.   Annals of the New York Academy of Sciences

Safety of the Surrogate MicroorganismEnterococcus faeciumNRRL B-2354 for Use in Thermal Process Validation

(2014) Lauren M. Kopit et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Safety assessment of the butyrate-producing Butyricicoccus pullicaecorum strain 25-3T, a potential probiotic for patients with inflammatory bowel disease, based on oral toxicity tests and whole genome sequencing

(2014) Marjan Steppe et al.   FOOD AND CHEMICAL TOXICOLOGY

Control of tyramine and histamine accumulation by lactic acid bacteria using bacteriocin forming lactococci

(2014) Giulia Tabanelli et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

(2014) Colin Hill et al.   Nature Reviews Gastroenterology & Hepatology

Strengths and Limitations of 16S rRNA Gene Amplicon Sequencing in Revealing Temporal Microbial Community Dynamics

(2014) Rachel Poretsky et al.   PLoS One

Variable Characteristics of Bacteriocin-Producing Streptococcus salivarius Strains Isolated from Malaysian Subjects

(2014) Abdelahhad Barbour et al.   PLoS One

Homologous overexpression of alkyl hydroperoxide reductase subunit C (ahpC) protects Bifidobacterium longum strain NCC2705 from oxidative stress

(2014) FangLei Zuo et al.   RESEARCH IN MICROBIOLOGY

The Comprehensive Antibiotic Resistance Database

(2013) Andrew G. McArthur et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Antimicrobial Susceptibility of Bacillus Strains Isolated from Primary Starters for African Traditional Bread Production and Characterization of the Bacitracin Operon and Bacitracin Biosynthesis

(2012) David B. Adimpong et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Pangenomics – an avenue to improved industrial starter cultures and probiotics

(2012) Christel Garrigues et al.   CURRENT OPINION IN BIOTECHNOLOGY

Effect of Chemico-Physical Parameters on the Histidine Decarboxylase (HdcA) Enzymatic Activity in Streptococcus thermophilus PRI60

(2012) Giulia Tabanelli et al.   JOURNAL OF FOOD SCIENCE

Ribosomal multilocus sequence typing: universal characterization of bacteria from domain to strain

(2012) K. A. Jolley et al.   MICROBIOLOGY-SGM

Probiotic metabolites fromBacillus coagulansGanedenBC30TMsupport maturation of antigen-presenting cellsin vitro

(2012) Kathleen F Benson   WORLD JOURNAL OF GASTROENTEROLOGY

Safety assessment ofBifidobacterium longumJDM301 based on complete genome sequences

(2012) Yan-Xia Wei   WORLD JOURNAL OF GASTROENTEROLOGY

Health Claims in Europe: Probiotics and Prebiotics as Case Examples

(2012) Henk van Loveren et al.   Annual Review of Food Science and Technology

Bacillus coagulans GBI-30, 6086 limits the recurrence of Clostridium difficile-Induced colitis following vancomycin withdrawal in mice

(2012) Leo R Fitzpatrick et al.   Gut Pathogens

Screening for Antimicrobial Resistance Genes and Virulence Factors via Genome Sequencing

(2011) Mads Bennedsen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

One-year chronic oral toxicity with combined reproduction toxicity study of a novel probiotic, Bacillus coagulans, as a food ingredient

(2011) J.R. Endres et al.   FOOD AND CHEMICAL TOXICOLOGY

Antibiotic resistance determinants in the interplay between food and gut microbiota

(2011) Chiara Devirgiliis et al.   Genes and Nutrition

Safety assessment of Lactobacillus plantarum JDM1 based on the complete genome

(2011) Zhuo-Yang Zhang et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Alternative Spermidine Biosynthetic Route Is Critical for Growth ofCampylobacter jejuniand Is the Dominant Polyamine Pathway in Human Gut Microbiota

(2011) Colin C. Hanfrey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors

(2011) L. Chen et al.   NUCLEIC ACIDS RESEARCH

Bacillus Coagulans GBI-30 (BC30) improves indices of Clostridium difficile-Induced colitis in mice

(2011) Leo R Fitzpatrick et al.   Gut Pathogens

Use of a continuous culture fermentation system to investigate the effect of GanedenBC30 (Bacillus coagulans GBI-30, 6086) supplementation on pathogen survival in the human gut microbiota

(2010) Harue Honda et al.   ANAEROBE

Horizontal gene transfer amongst probiotic lactic acid bacteria and other intestinal microbiota: what are the possibilities? A review

(2010) Carol A. van Reenen et al.   ARCHIVES OF MICROBIOLOGY

GanedenBC30™ cell wall and metabolites: anti-inflammatory and immune modulating effects in vitro

(2010) Gitte S Jensen et al.   BMC IMMUNOLOGY

Bacillus probiotics

(2010) Simon M. Cutting   FOOD MICROBIOLOGY

Effects of a propietary Bacillus coagulans preparation on symptoms of diarrhea-predominant irritable bowel syndrome

(2010) B.J. Dolin   METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY

CRISPR/Cas, the Immune System of Bacteria and Archaea

(2010) P. Horvath et al.   SCIENCE

Qualified presumption of safety (QPS): a generic risk assessment approach for biological agents notified to the European Food Safety Authority (EFSA)

(2010) Renata G.K. Leuschner et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

New approach for the detection of non-ribosomal peptide synthetase genes in Bacillus strains by polymerase chain reaction

(2009) Arthur Tapi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A prospective, randomized, double-blind, placebo-controlled parallel-group dual site trial to evaluate the effects of a Bacillus coagulans-based product on functional intestinal gas symptoms

(2009) Douglas S Kalman et al.   BMC GASTROENTEROLOGY

Safety assessment of a proprietary preparation of a novel Probiotic, Bacillus coagulans, as a food ingredient

(2009) J.R. Endres et al.   FOOD AND CHEMICAL TOXICOLOGY

An Alternative Polyamine Biosynthetic Pathway Is Widespread in Bacteria and Essential for Biofilm Formation inVibrio cholerae

(2009) Jeongmi Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Original Research:Bacillus coagulansSignificantly Improved Abdominal Pain and Bloating in Patients with IBS

(2009) Larysa Hun   POSTGRADUATE MEDICINE

Survival and metabolic activity of the GanedenBC30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine

(2009) A. Maathuis et al.   Beneficial Microbes

CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA

(2008) Luciano A. Marraffini et al.   SCIENCE

Biosafety assessment of probiotics used for human consumption: recommendations from the EU-PROSAFE project

(2007) Vanessa Vankerckhoven et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY