Photoacoustic imaging as a tool to probe the tumour microenvironment

Quantitatively Visualizing Tumor-Related Protease Activity in Vivo Using a Ratiometric Photoacoustic Probe

(2019) Ling Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A roadmap for the clinical implementation of optical-imaging biomarkers

(2019) Dale J. Waterhouse et al.   Nature Biomedical Engineering

Photoacoustic clinical imaging

(2019) Idan Steinberg et al.   Photoacoustics

Optoacoustics delineates murine breast cancer models displaying angiogenesis and vascular mimicry

(2018) Isabel Quiros-Gonzalez et al.   BRITISH JOURNAL OF CANCER

A peek into cancer-associated fibroblasts: origins, functions and translational impact

(2018) Valerie S. LeBleu et al.   Disease Models & Mechanisms

The metabolic axis of macrophage and immune cell polarization

(2018) Spencer A. Hobson-Gutierrez et al.   Disease Models & Mechanisms

Photoacoustic imaging to assess pixel-based sO2 distributions in experimental prostate tumors

(2018) Alina L. Bendinger et al.   JOURNAL OF BIOMEDICAL OPTICS

Scalable and massively parallel Monte Carlo photon transport simulations for heterogeneous computing platforms

(2018) Leiming Yu et al.   JOURNAL OF BIOMEDICAL OPTICS

Noninvasive photoacoustic and fluorescent tracking of optical dye labeled T cellular activities of diseased sites at new depth

(2018) Shuai Zheng et al.   Journal of Biophotonics

In vivo photoacoustic/ultrasonic dual-modality endoscopy with a miniaturized full field-of-view catheter

(2018) Yan Li et al.   Journal of Biophotonics

Adipocyte biology in breast cancer: From silent bystander to active facilitator

(2018) Junjeong Choi et al.   PROGRESS IN LIPID RESEARCH

A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists

(2018) Erin I. Neuschler et al.   RADIOLOGY

Downgrading of Breast Masses Suspicious for Cancer by Using Optoacoustic Breast Imaging

(2018) Gisela L. G. Menezes et al.   RADIOLOGY

Optoacoustic Imaging Detects Hormone-Related Physiological Changes of Breast Parenchyma

(2018) Oshaani Abeyakoon et al.   ULTRASCHALL IN DER MEDIZIN

Single-breath-hold photoacoustic computed tomography of the breast

(2018) Li Lin et al.   Nature Communications

Identifying intestinal fibrosis and inflammation by spectroscopic photoacoustic imaging: an animal study in vivo

(2018) Yunhao Zhu et al.   Biomedical Optics Express

Fast assessment of lipid content in arteries in vivo by intravascular photoacoustic tomography

(2018) Yingchun Cao et al.   Scientific Reports

Oxygen-enhanced and dynamic contrast-enhanced optoacoustic tomography provide surrogate biomarkers of tumour vascular function, hypoxia and necrosis.

(2018) Michal R Tomaszewski et al.   CANCER RESEARCH

Interferon-gamma PET Imaging as a Predictive Tool for Monitoring Response to Tumor Immunotherapy

(2018) Heather M Gibson et al.   CANCER RESEARCH

FAPI-PET/CT: biodistribution and preliminary dosimetry estimate of two DOTA-containing FAP-targeting agents in patients with various cancers

(2018) Frederik Giesel et al.   JOURNAL OF NUCLEAR MEDICINE

Organic Semiconducting Polymer Nanoparticles for Photoacoustic Labeling and Tracking of Stem Cells in the Second Near-Infrared Window

(2018) Chao Yin et al.   ACS Nano

Immune regulation of metastasis: mechanistic insights and therapeutic opportunities

(2018) Olga S. Blomberg et al.   Disease Models & Mechanisms

Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model

(2018) Denver D. Britto et al.   Disease Models & Mechanisms

Indocyanine Green labeling for optical and photoacoustic imaging of Mesenchymal Stem Cells after in vivo transplantation

(2018) M Filippi et al.   Journal of Biophotonics

Non-invasive imaging in dermatology and the unique potential of Raster-Scan Optoacoustic Mesoscopy (RSOM)

(2018) B. Hindelang et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Imaging of Cancer Immunotherapy: Current Approaches and Future Directions

(2018) Mizuki Nishino et al.   RADIOLOGY

Magnetic resonance elastography: basic principles, technique, and clinical applications in the liver

(2018) Habip Eser Akkaya et al.   Diagnostic and Interventional Radiology

Towards Quantitative Evaluation of Tissue Absorption Coefficients Using Light Fluence Correction in Optoacoustic Tomography

(2017) Frederic M. Brochu et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Exploration of melanoma metastases in mice brains using endogenous contrast photoacoustic imaging

(2017) Jonathan Lavaud et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Photoacoustic imaging using genetically encoded reporters: a review

(2017) Joanna Brunker et al.   JOURNAL OF BIOMEDICAL OPTICS

Evaluation of Precision in Optoacoustic Tomography for Preclinical Imaging in Living Subjects

(2017) James Joseph et al.   JOURNAL OF NUCLEAR MEDICINE

Development of Novel ImmunoPET Tracers to Image Human PD-1 Checkpoint Expression on Tumor-Infiltrating Lymphocytes in a Humanized Mouse Model

(2017) Arutselvan Natarajan et al.   MOLECULAR IMAGING AND BIOLOGY

The immune contexture in cancer prognosis and treatment

(2017) Wolf H. Fridman et al.   Nature Reviews Clinical Oncology

Multispectral Optoacoustic Tomography for Assessment of Crohn’s Disease Activity

(2017) Ferdinand Knieling et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting pH regulating proteins for cancer therapy–Progress and limitations

(2017) Scott K. Parks et al.   SEMINARS IN CANCER BIOLOGY

The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications

(2017) Masato Nakajima et al.   TUMOR BIOLOGY

In vivo quantitative imaging of tumor pH by nanosonophore assisted multispectral photoacoustic imaging

(2017) Janggun Jo et al.   Nature Communications

A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

(2017) Hailey J. Knox et al.   Nature Communications

Oxygen Enhanced Optoacoustic Tomography (OE-OT) Reveals Vascular Dynamics in Murine Models of Prostate Cancer

(2017) Michal R Tomaszewski et al.   Theranostics

Characterization of the Tumor Microenvironment and Tumor–Stroma Interaction by Non-invasive Preclinical Imaging

(2017) Nirilanto Ramamonjisoa et al.   Frontiers in Oncology

Visualization of tumor-related blood vessels in human breast by photoacoustic imaging system with a hemispherical detector array

(2017) M. Toi et al.   Scientific Reports

The hypoxic tumor microenvironment: A driving force for breast cancer progression

(2016) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cycling hypoxia: A key feature of the tumor microenvironment

(2016) Carine Michiels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Gadolinium-based contrast agent toxicity: a review of known and proposed mechanisms

(2016) Moshe Rogosnitzky et al.   BIOMETALS

Functional Flow Patterns and Static Blood Pooling in Tumors Revealed by Combined Contrast-Enhanced Ultrasound and Photoacoustic Imaging

(2016) A. Bar-Zion et al.   CANCER RESEARCH

Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap

(2016) J. Jason Morton et al.   CANCER RESEARCH

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds

(2016) Alejandra Bruna et al.   CELL

The state of the art in breast imaging using the Twente Photoacoustic Mammoscope: results from 31 measurements on malignancies

(2016) Michelle Heijblom et al.   EUROPEAN RADIOLOGY

Tumour angiogenesis-Origin of blood vessels

(2016) S. Krishna Priya et al.   INTERNATIONAL JOURNAL OF CANCER

Molecular Imaging of Inflammation: Current Status

(2016) D. A. Hammoud   JOURNAL OF NUCLEAR MEDICINE

Quantitative CD3 PET Imaging Predicts Tumor Growth Response to Anti-CTLA-4 Therapy

(2016) B. M. Larimer et al.   JOURNAL OF NUCLEAR MEDICINE

Predictive biomarkers for checkpoint inhibitor-based immunotherapy

(2016) Geoffrey T Gibney et al.   LANCET ONCOLOGY

The ever-expanding role of HIF in tumour and stromal biology

(2016) Edward L. LaGory et al.   NATURE CELL BIOLOGY

Contrast agents for molecular photoacoustic imaging

(2016) Judith Weber et al.   NATURE METHODS

A practical guide to photoacoustic tomography in the life sciences

(2016) Lihong V Wang et al.   NATURE METHODS

Tumor-associated fibroblasts predominantly come from local and not circulating precursors

(2016) Ainhoa Arina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of Tumor-associated Stroma and Its Relationship with Tumor Hypoxia Using Dynamic Contrast-enhanced CT and18F Misonidazole PET in Murine Tumor Models

(2016) Sho Koyasu et al.   RADIOLOGY

Imaging approaches to optimize molecular therapies

(2016) Ralph Weissleder et al.   Science Translational Medicine

Dynamic contrast enhanced CT in nodule characterization: How we review and report

(2016) Nagmi R. Qureshi et al.   CANCER IMAGING

Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system

(2016) Pim J. van den Berg et al.   Biomedical Optics Express

Velocity measurements in whole blood using acoustic resolution photoacoustic Doppler

(2016) Joanna Brunker et al.   Biomedical Optics Express

Characterizing intestinal inflammation and fibrosis in Crohn’s disease by photoacoustic imaging: feasibility study

(2016) Hao Lei et al.   Biomedical Optics Express

Photoacoustic monitoring of tumor and normal tissue response to radiation

(2016) Laurie J. Rich et al.   Scientific Reports

High-Resolution Multispectral Optoacoustic Tomography of the Vascularization and Constitutive Hypoxemia of Cancerous Tumors

(2016) Andrei Chekkoury et al.   NEOPLASIA

High Resolution Ultrasound and Photoacoustic Imaging of Orthotopic Lung Cancer in Mice: New Perspectives for Onco-Pharmacology

(2016) Florian Raes et al.   PLoS One

A Self-Assembled Albumin-Based Nanoprobe for In Vivo Ratiometric Photoacoustic pH Imaging

(2015) Qian Chen et al.   ADVANCED MATERIALS

Oxygen-Enhanced MRI Accurately Identifies, Quantifies, and Maps Tumor Hypoxia in Preclinical Cancer Models

(2015) J. P. B. O'Connor et al.   CANCER RESEARCH

Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy

(2015) R. Hughes et al.   CANCER RESEARCH

Photoacoustic Tomography Detects Early Vessel Regression and Normalization During Ovarian Tumor Response to the Antiangiogenic Therapy Trebananib

(2015) S. E. Bohndiek et al.   JOURNAL OF NUCLEAR MEDICINE

Multiscale photoacoustic tomography using reversibly switchable bacterial phytochrome as a near-infrared photochromic probe

(2015) Junjie Yao et al.   NATURE METHODS

Deep in vivo photoacoustic imaging of mammalian tissues using a tyrosinase-based genetic reporter

(2015) Amit P. Jathoul et al.   Nature Photonics

Engineering high-affinity PD-1 variants for optimized immunotherapy and immuno-PET imaging

(2015) Roy L. Maute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Patrolling monocytes control tumor metastasis to the lung

(2015) R. N. Hanna et al.   SCIENCE

T cell exclusion, immune privilege, and the tumor microenvironment

(2015) J. A. Joyce et al.   SCIENCE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Optimizing Hypoxia Detection and Treatment Strategies

(2015) Cameron J. Koch et al.   SEMINARS IN NUCLEAR MEDICINE

Multiparametric ultrasound in the detection of prostate cancer: a systematic review

(2015) Arnoud Postema et al.   WORLD JOURNAL OF UROLOGY

Specific imaging of atherosclerotic plaque lipids with two-wavelength intravascular photoacoustics

(2015) Min Wu et al.   Biomedical Optics Express

Photoacoustic image patterns of breast carcinoma and comparisons with Magnetic Resonance Imaging and vascular stained histopathology

(2015) M. Heijblom et al.   Scientific Reports

Combined Effects of Pericytes in the Tumor Microenvironment

(2015) Aline Lopes Ribeiro et al.   Stem Cells International

Pushing the Optical Imaging Limits of Cancer with Multi-Frequency-Band Raster-Scan Optoacoustic Mesoscopy (RSOM)

(2015) Murad Omar et al.   NEOPLASIA

Lessons from patient-derived xenografts for better in vitro modeling of human cancer

(2014) Stephen Yiu Chuen Choi et al.   ADVANCED DRUG DELIVERY REVIEWS

Dynamic Contrast-Enhanced CT and MRI for Pulmonary Nodule Assessment

(2014) Yoshiharu Ohno et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

The Role of Mechanical Forces in Tumor Growth and Therapy

(2014) Rakesh K. Jain et al.   Annual Review of Biomedical Engineering

Spectroscopic intravascular photoacoustic imaging of lipids in atherosclerosis

(2014) Krista Jansen et al.   JOURNAL OF BIOMEDICAL OPTICS

Late Imaging with [1-11C]Acetate Improves Detection of Tumor Fatty Acid Synthesis with PET

(2014) D. Y. Lewis et al.   JOURNAL OF NUCLEAR MEDICINE

Gold nanoparticles for in vivo cell tracking

(2014) Rinat Meir et al.   Nanomedicine

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Remodelling the extracellular matrix in development and disease

(2014) Caroline Bonnans et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Immune cell imaging using multi-spectral optoacoustic tomography

(2014) Stratis Tzoumas et al.   OPTICS LETTERS

Engineered antibody fragments for immuno-PET imaging of endogenous CD8+ T cells in vivo

(2014) R. Tavare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Multiparametric Spectroscopic Photoacoustic Imaging of Breast Cancer Development in a Transgenic Mouse Model

(2014) Katheryne E. Wilson et al.   Theranostics

Real-Time Assessment of Tissue Hypoxia In Vivo with Combined Photoacoustics and High-Frequency Ultrasound

(2014) Marco Gerling et al.   Theranostics

Acidity Generated by the Tumor Microenvironment Drives Local Invasion

(2013) V. Estrella et al.   CANCER RESEARCH

Molecular Photoacoustic Imaging of Follicular Thyroid Carcinoma

(2013) J. Levi et al.   CLINICAL CANCER RESEARCH

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

(2013) F. Baenke et al.   Disease Models & Mechanisms

Hypoxia-inducible Factor 1 (HIF-1) Promotes Extracellular Matrix Remodeling under Hypoxic Conditions by InducingP4HA1, P4HA2,andPLOD2Expression in Fibroblasts

(2013) Daniele M. Gilkes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activatable Oligomerizable Imaging Agents for Photoacoustic Imaging of Furin-Like Activity in Living Subjects

(2013) Anca Dragulescu-Andrasi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Correlations of noninvasive BOLD and TOLD MRI with pO2and relevance to tumor radiation response

(2013) Rami R. Hallac et al.   MAGNETIC RESONANCE IN MEDICINE

Dedicated 3D photoacoustic breast imaging

(2013) Robert A. Kruger et al.   MEDICAL PHYSICS

Procollagen Lysyl Hydroxylase 2 Is Essential for Hypoxia-Induced Breast Cancer Metastasis

(2013) Daniele M. Gilkes et al.   MOLECULAR CANCER RESEARCH

The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis

(2013) Kun Zhang et al.   NATURE CELL BIOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Development and Application of Stable Phantoms for the Evaluation of Photoacoustic Imaging Instruments

(2013) Sarah E. Bohndiek et al.   PLoS One

Current MR Imaging Lipid Detection Techniques for Diagnosis of Lesions in the Abdomen and Pelvis

(2013) Sajal S. Pokharel et al.   RADIOGRAPHICS

PET Imaging of Inflammation Biomarkers

(2013) Chenxi Wu et al.   Theranostics

Tenascin-C Downregulates Wnt Inhibitor Dickkopf-1, Promoting Tumorigenesis in a Neuroendocrine Tumor Model

(2013) Falk Saupe et al.   Cell Reports

Modulation of Microenvironment Acidity Reverses Anergy in Human and Murine Tumor-Infiltrating T Lymphocytes

(2012) A. Calcinotto et al.   CANCER RESEARCH

Heterogeneity of the tumor vasculature: the need for new tumor blood vessel type-specific targets

(2012) Janice A. Nagy et al.   CLINICAL & EXPERIMENTAL METASTASIS

Predictive Impact of Circulating Vascular Endothelial Growth Factor in Four Phase III Trials Evaluating Bevacizumab

(2012) P. S. Hegde et al.   CLINICAL CANCER RESEARCH

In vivo preclinical photoacoustic imaging of tumor vasculature development and therapy

(2012) Jan Laufer et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantitative spectroscopic photoacoustic imaging: a review

(2012) Ben Cox et al.   JOURNAL OF BIOMEDICAL OPTICS

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs

(2012) L. V. Wang et al.   SCIENCE

In vivo Intravascular Ultrasound-guided Photoacoustic Imaging of Lipid in Plaques Using an Animal Model of Atherosclerosis

(2012) Bo Wang et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Functional photoacoustic microscopy of pH

(2011) Muhammad Rameez Chatni et al.   JOURNAL OF BIOMEDICAL OPTICS

Biomedical photoacoustic imaging

(2011) P. Beard   Interface Focus

pH control mechanisms of tumor survival and growth

(2010) Scott K. Parks et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Quantitative Parametric Perfusion Images Using 15O-Labeled Water and a Clinical PET/CT Scanner: Test-Retest Variability in Lung Cancer

(2010) A. A. M. van der Veldt et al.   JOURNAL OF NUCLEAR MEDICINE

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serum Fatty Acid Synthase as a Marker of Pancreatic Neoplasia

(2009) K. Walter et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

In situ Expression of Tumor Antigens by Messenger RNA-Electroporated Dendritic Cells in Lymph Nodes of Melanoma Patients

(2009) D. H. Schuurhuis et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Non-Invasive Molecular Imaging of Fibrosis Using a Collagen-Targeted Peptidomimetic of the Platelet Collagen Receptor Glycoprotein VI

(2009) Julien Muzard et al.   PLoS One

MR Elastography of Liver Tumors: Preliminary Results

(2008) Sudhakar K. Venkatesh et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Control of Cell Growth and Survival by Enzymes of the Fatty Acid Synthesis Pathway in HCT-116 Colon Cancer Cells

(2008) Y. Zhan et al.   CLINICAL CANCER RESEARCH

Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

(2008) Christian Stockmann et al.   NATURE

Noninvasive photoacoustic imaging of the developing vasculature during early tumor growth

(2008) Yeqi Lao et al.   PHYSICS IN MEDICINE AND BIOLOGY

Simultaneous Molecular and Hypoxia Imaging of Brain Tumors In Vivo Using Spectroscopic Photoacoustic Tomography

(2008) Meng-Lin Li et al.   PROCEEDINGS OF THE IEEE

Contrast safety in the cancer patient: preventing contrast-induced nephropathy

(2008) Jay P. Heiken   CANCER IMAGING