A bioreducible N-oxide-based probe for photoacoustic imaging of hypoxia

H2O2-responsive liposomal nanoprobe for photoacoustic inflammation imaging and tumor theranostics via in vivo chromogenic assay

(2017) Qian Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photoacoustic probes for real-time tracking of endogenous H2S in living mice

(2017) Ben Shi et al.   Chemical Science

A universal fluorogenic switch for Fe(ii) ion based on N-oxide chemistry permits the visualization of intracellular redox equilibrium shift towards labile iron in hypoxic tumor cells

(2017) Tasuku Hirayama et al.   Chemical Science

Activatable Photoacoustic Nanoprobes for In Vivo Ratiometric Imaging of Peroxynitrite

(2016) Jianjian Zhang et al.   ADVANCED MATERIALS

Near-Infrared Photoacoustic Imaging Probe Responsive to Calcium

(2016) Anurag Mishra et al.   ANALYTICAL CHEMISTRY

Mitochondrial Nitroreductase Activity Enables Selective Imaging and Therapeutic Targeting

(2016) Arnaud Chevalier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A practical guide to photoacoustic tomography in the life sciences

(2016) Lihong V Wang et al.   NATURE METHODS

Peripheral Artery Disease

(2016) Iftikhar J. Kullo et al.   NEW ENGLAND JOURNAL OF MEDICINE

CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes

(2016) Liam J. O’Connor et al.   ACS Central Science

Parts per billion detection of uranium with a porphyrinoid-containing nanoparticle and in vivo photoacoustic imaging

(2015) I-Ting Ho et al.   ANALYST

A Bioorthogonal Reaction ofN-Oxide and Boron Reagents

(2015) Justin Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting Tumor Hypoxia With Hypoxia-Activated Prodrugs

(2015) Jen Jen Yeh et al.   JOURNAL OF CLINICAL ONCOLOGY

Photoacoustic Probes for Ratiometric Imaging of Copper(II)

(2015) Hao Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Optimizing Hypoxia Detection and Treatment Strategies

(2015) Cameron J. Koch et al.   SEMINARS IN NUCLEAR MEDICINE

PHOTOACOUSTIC TOMOGRAPHY: PRINCIPLES AND ADVANCES (Invited Review)

(2015) Jun Xia et al.   Progress in Electromagnetics Research-PIER

Imaging tumour hypoxia with positron emission tomography

(2014) I N Fleming et al.   BRITISH JOURNAL OF CANCER

Light In and Sound Out: Emerging Translational Strategies for Photoacoustic Imaging

(2014) S. Zackrisson et al.   CANCER RESEARCH

Real-time imaging of oxidative and nitrosative stress in the liver of live animals for drug-toxicity testing

(2014) Adam J Shuhendler et al.   NATURE BIOTECHNOLOGY

Development of Azo-Based Fluorescent Probes to Detect Different Levels of Hypoxia

(2013) Wen Piao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Role of hypoxia-inducible factors in breast cancer metastasis

(2013) Daniele M Gilkes et al.   Future Oncology

Activatable Oligomerizable Imaging Agents for Photoacoustic Imaging of Furin-Like Activity in Living Subjects

(2013) Anca Dragulescu-Andrasi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells

(2012) Shodai Takahashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A highly selective turn-on fluorescent probe for iron(ii) to visualize labile iron in living cells

(2012) Tasuku Hirayama et al.   Chemical Science

Hypoxia and hypoxia inducible factors: Diverse roles in liver diseases

(2011) Bharath Nath et al.   HEPATOLOGY

The mechanism of enzymatic and non-enzymatic N-oxide reductive metabolism of cyadox in pig liver

(2011) Ming Zheng et al.   XENOBIOTICA

Hypoxia-Sensitive Fluorescent Probes forin VivoReal-Time Fluorescence Imaging of Acute Ischemia

(2010) Kazuki Kiyose et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design, Synthesis, and Imaging of an Activatable Photoacoustic Probe

(2010) Jelena Levi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor Hypoxia Imaging

(2010) Xilin Sun et al.   MOLECULAR IMAGING AND BIOLOGY

Efficient Hypoxic Activation of the Anticancer Agent AQ4N by CYP2S1 and CYP2W1

(2010) C. R. Nishida et al.   MOLECULAR PHARMACOLOGY

Going deeper than microscopy: the optical imaging frontier in biology

(2010) Vasilis Ntziachristos   NATURE METHODS

Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia

(2009) Shinae Kizaka-Kondoh et al.   CANCER SCIENCE

Serial Noninvasive Targeted Imaging of Peripheral Angiogenesis: Validation and Application of a Semiautomated Quantitative Approach

(2009) L. W. Dobrucki et al.   JOURNAL OF NUCLEAR MEDICINE

Ferritins: A family of molecules for iron storage, antioxidation and more

(2008) Paolo Arosio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hypoxia-Selective Targeting by the Bioreductive Prodrug AQ4N in Patients with Solid Tumors: Results of a Phase I Study

(2008) M. R. Albertella et al.   CLINICAL CANCER RESEARCH

Targeted imaging of hypoxia-induced integrin activation in myocardium early after infarction

(2008) Leszek Kalinowski et al.   JOURNAL OF APPLIED PHYSIOLOGY

Reductive Heme-Dependent Activation of theN-Oxide Prodrug AQ4N by Nitric Oxide Synthase

(2008) Clinton R. Nishida et al.   JOURNAL OF MEDICINAL CHEMISTRY