Targeting asparagine and autophagy for pulmonary adenocarcinoma therapy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Inhibition of autophagy overcomes the nanotoxicity elicited by cadmium-based quantum dots

(2016) Jiajun Fan et al.   BIOMATERIALS

L-asparaginase as a critical component to combat Acute Lymphoblastic Leukaemia (ALL): A novel approach to target ALL

(2016) Usman Ali et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Autophagy is involved in regulating the immune response of dendritic cells to influenza A (H1N1) pdm09 infection

(2016) Farong Zang et al.   IMMUNOLOGY

Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies

(2016) Maria Xilouri et al.   MOVEMENT DISORDERS

Asparaginase Erwinia chrysanthemi as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia who have developed hypersensitivity to E. coli-derived asparaginase

(2016) Lisa Figueiredo et al.   Expert Review of Hematology

Downregulation of TFAM inhibits the tumorigenesis of non-small cell lung cancer by activating ROS-mediated JNK/p38MAPK signaling and reducing cellular bioenergetics

(2016) Deyao Xie et al.   Oncotarget

Hernandezine, a novel AMPK activator induces autophagic cell death in drug-resistant cancers

(2016) Betty Yuen Kwan Law et al.   Oncotarget

A Comprehensive Review on l-Asparaginase and Its Applications

(2015) Tahira Batool et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

The role of autophagy in the cytotoxicity induced by recombinant human arginase in laryngeal squamous cell carcinoma

(2015) Chen Lin et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Targeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemia

(2015) Xian Zeng et al.   Autophagy

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy

(2015) Jun He et al.   Autophagy

Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells

(2015) Hui Li et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Inherited genetic variation in childhood acute lymphoblastic leukemia

(2015) T. Moriyama et al.   BLOOD

Ligand-Independent EGFR Signaling

(2015) G. Guo et al.   CANCER RESEARCH

Primary Treatment Options for High-Risk/Medically Inoperable Early Stage NSCLC Patients

(2015) Guy C. Jones et al.   Clinical Lung Cancer

Adjuvant therapy for EGFR mutant and ALK positive NSCLC: Current data and future prospects

(2015) Jody C. Chuang et al.   LUNG CANCER

Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine

(2015) Elizabeth Emma Palmer et al.   MOLECULAR GENETICS AND METABOLISM

Selective Intracellular Delivery of Recombinant Arginine Deiminase (ADI) Using pH-Sensitive Cell Penetrating Peptides To Overcome ADI Resistance in Hypoxic Breast Cancer Cells

(2015) Tzyy-Harn Yeh et al.   MOLECULAR PHARMACEUTICS

Autophagy mediates degradation of nuclear lamina

(2015) Zhixun Dou et al.   NATURE

Inhibition of Autophagy Potentiated the Antitumor Effect of Nedaplatin in Cisplatin-Resistant Nasopharyngeal Carcinoma Cells

(2015) Zhongyu Liu et al.   PLoS One

A novel therapeutic approach against B-cell non-Hodgkin’s lymphoma through co-inhibition of Hedgehog signaling pathway and autophagy

(2015) Jiajun Fan et al.   TUMOR BIOLOGY

Asparagine requirement in Plasmodium berghei as a target to prevent malaria transmission and liver infections

(2015) Viswanathan A. Nagaraj et al.   Nature Communications

A current review of folate receptor alpha as a potential tumor target in non-small-cell lung cancer

(2015) Zhehai Wang et al.   Drug Design Development and Therapy

Asparaginase induces apoptosis and cytoprotective autophagy in chronic myeloid leukemia cells

(2015) Ping Song et al.   Oncotarget

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

The core autophagy protein ATG4B is a potential biomarker and therapeutic target in CML stem/progenitor cells

(2014) K. Rothe et al.   BLOOD

Asparagine Synthetase Polymorphisms and Toxicity and Efficacy of Asparaginases

(2014) V. I. Avramis   CLINICAL CANCER RESEARCH

L-asparaginase induces in AML U937 cells apoptosis via an AIF-mediated mechanism

(2014) Yingyi He   Frontiers in Bioscience-Landmark

Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells

(2014) Z Wang et al.   Cell Death & Disease

Asparagine synthetase: regulation by cell stress and involvement in tumor biology

(2013) Mukundh N. Balasubramanian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Genetics and biomarkers in personalisation of lung cancer treatment

(2013) Rafael Rosell et al.   LANCET

Autophagy Plays a Critical Role in ChLym-1-Induced Cytotoxicity of Non-Hodgkin’s Lymphoma Cells

(2013) Jiajun Fan et al.   PLoS One

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells

(2012) Y Yu et al.   LEUKEMIA

Arginine Deprivation, Autophagy, Apoptosis (AAA) for the Treatment of Melanoma

(2010) N. Savaraj et al.   CURRENT MOLECULAR MEDICINE

Autophagy basics

(2010) Isei Tanida   MICROBIOLOGY AND IMMUNOLOGY

ADI, autophagy and apoptosis: Metabolic stress as a therapeutic option for prostate cancer

(2009) Randie H. Kim et al.   Autophagy

Asparagine synthetase is a predictive biomarker of l-asparaginase activity in ovarian cancer cell lines

(2008) Philip L. Lorenzi et al.   MOLECULAR CANCER THERAPEUTICS