Three J-proteins impact Hsp104-mediated variant-specific prion elimination: a new critical role for a low-complexity domain

Impact of Amyloid Polymorphism on Prion-Chaperone Interactions in Yeast

(2019) Andrea N. Killian et al.   Viruses-Basel

Pop2 phosphorylation at S39 contributes to the glucose repression of stress response genes, HSP12 and HSP26

(2019) Pham Thi Kim Lien et al.   PLoS One

Anti-Prion Systems in Yeast and Inositol Polyphosphates

(2018) Reed B. Wickner et al.   BIOCHEMISTRY

Protein Regulation by Intrinsically Disordered Regions: A Role for Subdomains in the IDR of the HIV-1 Rev Protein

(2018) Ofrah Faust et al.   CHEMBIOCHEM

A reversible liquid drop aggregation controls glucose response in yeast

(2018) Kobi Simpson-Lavy et al.   CURRENT GENETICS

A prion-like domain in Hsp42 drives chaperone-facilitated aggregation of misfolded proteins

(2018) Tomas Grousl et al.   JOURNAL OF CELL BIOLOGY

Variant-specific and reciprocal Hsp40 functions in Hsp104-mediated prion elimination

(2018) Michael T. Astor et al.   MOLECULAR MICROBIOLOGY

Curing of [PSI+] by Hsp104 Overexpression: Clues to solving the puzzle

(2018) Lois E. Greene et al.   Prion

Chaperone functional specificity promotes yeast prion diversity

(2018) Andrea N. Killian et al.   PLoS Pathogens

Heat shock protein 104 (Hsp104)-mediated curing of [PSI+] yeast prions depends on both [PSI+] conformation and the properties of the Hsp104 homologs

(2017) Xiaohong Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Over-expression of the molecular chaperone Hsp104 inSaccharomyces cerevisiaeresults in the malpartition of [PSI+] propagons

(2017) Frederique Ness et al.   MOLECULAR MICROBIOLOGY

Prion-specific Hsp40 function: The role of the auxilin homolog Swa2

(2017) Emily E. Oliver et al.   Prion

How Do J-Proteins Get Hsp70 to Do So Many Different Things?

(2017) Elizabeth A. Craig et al.   TRENDS IN BIOCHEMICAL SCIENCES

Synthesis and evaluation of MR probes for targeted-reporter imaging

(2017) Kirti Dhingra Verma et al.   Chemical Science

The Pivotal Role of Protein Phosphorylation in the Control of Yeast Central Metabolism

(2017) Panayotis Vlastaridis et al.   G3-Genes Genomes Genetics

Broadening the functionality of a J-protein/Hsp70 molecular chaperone system

(2017) Brenda A. Schilke et al.   PLoS Genetics

Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation

(2016) Adam L Yokom et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation

(2016) Adam L Yokom et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Yeast Prions: Structure, Biology, and Prion-Handling Systems

(2015) Reed B. Wickner et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Swa2, the yeast homolog of mammalian auxilin, is specifically required for the propagation of the prion variant [URE3-1]

(2015) Elizabeth M. Troisi et al.   MOLECULAR MICROBIOLOGY

Hsp40 function in yeast prion propagation: Amyloid diversity necessitates chaperone functional complexity

(2015) Zachary A Sporn et al.   Prion

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Hsp104 Overexpression Cures Saccharomyces cerevisiae [ PSI + ] by Causing Dissolution of the Prion Seeds

(2014) Yang-Nim Park et al.   EUKARYOTIC CELL

Prion-like determinant [NSI +] decreases the expression of the SUP45 gene in Saccharomyces cerevisiae

(2014) A. M. Kondrashkina et al.   MOLECULAR BIOLOGY

Functional Diversification of Hsp40: Distinct J-Protein Functional Requirements for Two Prions Allow for Chaperone-Dependent Prion Selection

(2014) Julia M. Harris et al.   PLoS Genetics

Extensive Diversity of Prion Strains Is Defined by Differential Chaperone Interactions and Distinct Amyloidogenic Regions

(2014) Kevin C. Stein et al.   PLoS Genetics

Biology and Genetics of Prions Causing Neurodegeneration

(2013) Stanley B. Prusiner   Annual Review of Genetics

A Network of Cytosolic Factors Targets SRP-Independent Proteins to the Endoplasmic Reticulum

(2013) Tslil Ast et al.   CELL

Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion

(2013) Daniel L. Holmes et al.   CELL

Multisteric Regulation by Structural Disorder in Modular Signaling Proteins: An Extension of the Concept of Allostery

(2013) Peter Tompa   CHEMICAL REVIEWS

Sequential Duplications of an Ancient Member of the DnaJ-Family Expanded the Functional Chaperone Network in the Eukaryotic Cytosol

(2013) Chandan Sahi et al.   MOLECULAR BIOLOGY AND EVOLUTION

Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

(2013) Danielle L Swaney et al.   NATURE METHODS

Prions in Yeast

(2012) S. W. Liebman et al.   GENETICS

Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

(2012) Juliane Winkler et al.   JOURNAL OF CELL BIOLOGY

Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperones

(2012) Anne T. Gillies et al.   Molecular BioSystems

Influence of prion variant and yeast strain variation on prion-molecular chaperone requirements

(2012) Justin K. Hines et al.   Prion

A new perspective on Hsp104-mediated propagation and curing of the yeast prion [PSI+]

(2012) Christopher W. Helsen et al.   Prion

Molecular Chaperone Hsp104 Can Promote Yeast Prion Generation

(2011) Dmitry S. Kryndushkin et al.   GENETICS

The sensitive [SWI+] prion

(2011) Justin K. Hines et al.   Prion

[SWI+], the Prion Formed by the Chromatin Remodeling Factor Swi1, Is Highly Sensitive to Alterations in Hsp70 Chaperone System Activity

(2011) Justin K. Hines et al.   PLoS Genetics

[NSI +]: a novel non-Mendelian nonsense suppressor determinant in Saccharomyces cerevisiae

(2010) Alsu F. Saifitdinova et al.   CURRENT GENETICS

SUMOylation of the GTPase Rac1 is required for optimal cell migration

(2010) Sonia Castillo-Lluva et al.   NATURE CELL BIOLOGY

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Motor Mechanism for Protein Threading through Hsp104

(2009) Petra Wendler et al.   MOLECULAR CELL

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

(2009) Basant K. Patel et al.   NATURE CELL BIOLOGY

Heat Shock Protein 40: Structural Studies and Their Functional Implications

(2009) Jingzhi Li et al.   PROTEIN AND PEPTIDE LETTERS

Regulation of Thermotolerance by Stress-Induced Transcription Factors inSaccharomyces cerevisiae

(2008) Noritaka Yamamoto et al.   EUKARYOTIC CELL

In Vivo Monitoring of the Prion Replication Cycle Reveals a Critical Role for Sis1 in Delivering Substrates to Hsp104

(2008) Kimberly A. Tipton et al.   MOLECULAR CELL

Newly identified prion linked to the chromatin-remodeling factor Swi1 in Saccharomyces cerevisiae

(2008) Zhiqiang Du et al.   NATURE GENETICS

Protein disaggregation by the AAA+ chaperone ClpB involves partial threading of looped polypeptide segments

(2008) Tobias Haslberger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Specificity of the J-protein Sis1 in the propagation of 3 yeast prions

(2008) T. Higurashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA