Toxoplasma gondii induces prolonged host epidermal growth factor receptor signalling to prevent parasite elimination by autophagy: Perspectives for in vivo control of the parasite

Epidermal growth factor receptor promotes cerebral and retinal invasion by Toxoplasma gondii

(2019) Yalitza Lopez Corcino et al.   Scientific Reports

CD40 in endothelial cells restricts neural tissue invasion by Toxoplasma gondii

(2019) Jose-Andres C. Portillo et al.   INFECTION AND IMMUNITY

Patterns, Receptors, and Signals: Regulation of Phagosome Maturation

(2017) Anne-Marie Pauwels et al.   TRENDS IN IMMUNOLOGY

Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy

(2017) Jose-Andres C. Portillo et al.   PLoS Pathogens

Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer

(2017) Zhaoyun Liu et al.   PLoS One

Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages

(2016) Elizabeth Liu et al.   INFECTION AND IMMUNITY

Clinically Available Medicines Demonstrating Anti-Toxoplasma Activity

(2015) Andrew J. Neville et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer

(2015) Wei Wen et al.   Molecular Cancer

The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy

(2014) Jayoung Choi et al.   IMMUNITY

Activation of Protein Kinase C-  and Src Kinase Increases Urea Transporter A1  -2, 6 Sialylation

(2014) X. Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth

(2014) Sarah A. Stanley et al.   PLoS Pathogens

Scheduling of paclitaxel and gefitinib to inhibit repopulation for optimal treatment of human cancer cells and xenografts that overexpress the epidermal growth factor receptor

(2013) Andrea S. Fung et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A Host GPCR Signaling Network Required for the Cytolysis of Infected Cells Facilitates Release of Apicomplexan Parasites

(2013) Melanie G. Millholland et al.   Cell Host & Microbe

Klebsiella pneumoniaetargets an EGF receptor-dependent pathway to subvert inflammation

(2013) Christian G. Frank et al.   CELLULAR MICROBIOLOGY

CD40 Induces Anti-Toxoplasma gondii Activity in Nonhematopoietic Cells Dependent on Autophagy Proteins

(2013) Jennifer Van Grol et al.   INFECTION AND IMMUNITY

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

The Protein Kinase Double-Stranded RNA-Dependent (PKR) Enhances Protection against Disease Cause by a Non-Viral Pathogen

(2013) Pauline Sebby Ogolla et al.   PLoS Pathogens

Toxoplasma gondii-Induced Activation of EGFR Prevents Autophagy Protein-Mediated Killing of the Parasite

(2013) Luis Muniz-Feliciano et al.   PLoS Pathogens

Epidermal growth factor receptor is a preferred target for treating Amyloid- -induced memory loss

(2012) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis

(2011) Ruth J. Napier et al.   Cell Host & Microbe

The moving junction of apicomplexan parasites: a key structure for invasion

(2011) Sébastien Besteiro et al.   CELLULAR MICROBIOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

The CD40-Autophagy Pathway Is Needed for Host Protection Despite IFN-Γ-Dependent Immunity and CD40 Induces Autophagy via Control of P21 Levels

(2011) Jose-Andres C. Portillo et al.   PLoS One

Toxoplasma gondii Rhoptry Kinase ROP16 Activates STAT3 and STAT6 Resulting in Cytokine Inhibition and Arginase-1-Dependent Growth Control

(2011) Barbara A. Butcher et al.   PLoS Pathogens

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Avirulent Uracil Auxotrophs Based on Disruption of Orotidine-5'-Monophosphate Decarboxylase Elicit Protective Immunity to Toxoplasma gondii

(2010) B. A. Fox et al.   INFECTION AND IMMUNITY

EGF receptor activation by GPCRs: An universal pathway reveals different versions

(2010) Claus Liebmann   MOLECULAR AND CELLULAR ENDOCRINOLOGY

EGFR Signaling and Drug Discovery

(2010) Georg Lurje et al.   ONCOLOGY

The Epidermal Growth Factor Receptor (EGFR) Promotes Uptake of Influenza A Viruses (IAV) into Host Cells

(2010) Thorsten Eierhoff et al.   PLoS Pathogens

Membrane-anchored growth factors, the epidermal growth factor family: Beyond receptor ligands

(2008) Shigeki Higashiyama et al.   CANCER SCIENCE

Two conventional protein kinase C isoforms, α and βI, are involved in the ATP-induced activation of volume-regulated anion channel and glutamate release in cultured astrocytes

(2008) Alena Rudkouskaya et al.   JOURNAL OF NEUROCHEMISTRY

Kinase-Inactivated ULK Proteins Inhibit Autophagy via Their Conserved C-Terminal Domains Using an Atg13-Independent Mechanism

(2008) E. Y. W. Chan et al.   MOLECULAR AND CELLULAR BIOLOGY