Klebsiella pneumoniaetargets an EGF receptor-dependent pathway to subvert inflammation

Lipopolysaccharide O1 Antigen Contributes to the Virulence in Klebsiella pneumoniae Causing Pyogenic Liver Abscess

(2012) Pei-Fang Hsieh et al.   PLoS One

Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF- B network

(2012) K. M. Holmes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Z’ Factor including siRNA design quality parameter in RNAi screening experiments

(2012) Sławomir Mazur et al.   RNA Biology

CYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating Akt

(2012) Jae Hyang Lim et al.   Nature Communications

Subversion of innate immune responses by bacterial hindrance of NF-κB pathway

(2011) Gaëlle Le Negrate   CELLULAR MICROBIOLOGY

Involvement of Epidermal Growth Factor Receptor-Linked Signaling Responses in Pseudomonas fluorescens-Infected Alveolar Epithelial Cells

(2011) Hye Jin Choi et al.   INFECTION AND IMMUNITY

High Throughput Short Interfering RNA (siRNA) Screening of the Human Kinome Identifies Novel Kinases Controlling the Canonical Nuclear Factor-κB (NF-κB) Activation Pathway

(2011) Sanjeev Choudhary et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Klebsiella pneumoniaeOuter Membrane Protein A Is Required to Prevent the Activation of Airway Epithelial Cells

(2011) Catalina March et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Immunological Characterization of the Capsular Polysaccharide of a Pyrogenic Liver Abscess Caused byKlebsiella pneumoniae

(2011) Feng-Ling Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Arie Hoogendijk et al.   MOLECULAR MEDICINE

Modulation of NF-κB signalling by microbial pathogens

(2011) Masmudur M. Rahman et al.   NATURE REVIEWS MICROBIOLOGY

The Rate of NF-κB Nuclear Translocation Is Regulated by PKA and A Kinase Interacting Protein 1

(2011) Charles C. King et al.   PLoS One

Activation of Epidermal Growth Factor Receptor Is Required for NTHi-Induced NF-κB-Dependent Inflammation

(2011) Xiangbin Xu et al.   PLoS One

High-throughput and single-cell imaging of NF-κB oscillations using monoclonal cell lines

(2010) Sina Bartfeld et al.   BMC CELL BIOLOGY

Klebsiella pneumoniae subverts the activation of inflammatory responses in a NOD1-dependent manner

(2010) Verónica Regueiro et al.   CELLULAR MICROBIOLOGY

Glycogen synthase kinase 3: A point of convergence for the host inflammatory response

(2010) Huizhi Wang et al.   CYTOKINE

Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2

(2010) C. W. Wieland et al.   EUROPEAN RESPIRATORY JOURNAL

A-kinase-interacting Protein 1 (AKIP1) Acts as a Molecular Determinant of PKA in NF-κB Signaling

(2010) Nan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transactivation of the Epidermal Growth Factor Receptor by Heat Shock Protein 90 via Toll-like Receptor 4 Contributes to the Migration of Glioblastoma Cells

(2010) Dominique Thuringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored

(2010) D. Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Ubiquitin chain cleavage: CYLD at work

(2010) Ramin Massoumi   TRENDS IN BIOCHEMICAL SCIENCES

Pathogen recognition in the innate immune response

(2009) Himanshu Kumar et al.   BIOCHEMICAL JOURNAL

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Klebsiella pneumoniae Capsule Polysaccharide Impedes the Expression of  -Defensins by Airway Epithelial Cells

(2009) D. Moranta et al.   INFECTION AND IMMUNITY

Both TRIF- and MyD88-Dependent Signaling Contribute to Host Defense against Pulmonary Klebsiella Infection

(2009) S. Cai et al.   JOURNAL OF IMMUNOLOGY

The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria

(2009) Patrice Nordmann et al.   LANCET INFECTIOUS DISEASES

Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment

(2009) Minsoo Kim et al.   NATURE

Statistical methods for analysis of high-throughput RNA interference screens

(2009) Amanda Birmingham et al.   NATURE METHODS

Virulent Clones of Klebsiella pneumoniae: Identification and Evolutionary Scenario Based on Genomic and Phenotypic Characterization

(2009) Sylvain Brisse et al.   PLoS One

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

(2008) Jonathan L. Koff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Klebsiella pneumoniae OmpA Confers Resistance to Antimicrobial Peptides

(2008) E. Llobet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Klebsiella pneumoniae Increases the Levels of Toll-Like Receptors 2 and 4 in Human Airway Epithelial Cells

(2008) V. Regueiro et al.   INFECTION AND IMMUNITY

TLR4 Signaling Is Coupled to SRC Family Kinase Activation, Tyrosine Phosphorylation of Zonula Adherens Proteins, and Opening of the Paracellular Pathway in Human Lung Microvascular Endothelia

(2008) Ping Gong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capsule polysaccharide is a bacterial decoy for antimicrobial peptides

(2008) E. Llobet et al.   MICROBIOLOGY-SGM

RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF- B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes

(2008) D. E. Nowak et al.   MOLECULAR AND CELLULAR BIOLOGY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE

Host-Directed Drug Targeting of Factors Hijacked by Pathogens

(2008) A. Schwegmann et al.   Science Signaling

Signaling through cAMP and cAMP-dependent protein kinase: Diverse strategies for drug design

(2007) Susan S. Taylor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS