Lysine methylation signaling of non-histone proteins in the nucleus
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Title
Lysine methylation signaling of non-histone proteins in the nucleus
Authors
Keywords
Post-translational modifications (PTMs), Protein lysine methyltransferases (PKMTs), Lysine methylation, Non-histone methylation, Methylation signaling
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 76, Issue 15, Pages 2873-2883
Publisher
Springer Science and Business Media LLC
Online
2019-05-23
DOI
10.1007/s00018-019-03142-0
References
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Note: Only part of the references are listed.- The methyltransferase SETD6 regulates Mitotic progression through PLK1 methylation
- (2019) Michal Feldman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Enhanced PKMT-substrate recognition through non active-site interactions
- (2018) Margarita Kublanovsky et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- SETD3 negatively regulates VEGF expression during hypoxic pulmonary hypertension in rats
- (2018) Xiufeng Jiang et al. HYPERTENSION RESEARCH
- Functional Regulation of PPARs through Post-Translational Modifications
- (2018) Reinhard Brunmeir et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular pathways involved in the transport of nuclear receptors from the nucleus to cytoplasm
- (2018) Angeles C. Tecalco-Cruz JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
- (2018) Lei Bao et al. NUCLEIC ACIDS RESEARCH
- Methylated DNMT1 and E2F1 are targeted for proteolysis by L3MBTL3 and CRL4DCAF5 ubiquitin ligase
- (2018) Feng Leng et al. Nature Communications
- The nuclear receptor superfamily: A structural perspective
- (2018) Emily R. Weikum et al. PROTEIN SCIENCE
- EZH2 promotes DNA replication by stabilizing interaction of POLδ and PCNA via methylation-mediated PCNA trimerization
- (2018) Peng A et al. Epigenetics & Chromatin
- Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8
- (2018) Takeshi Tsusaka et al. Epigenetics & Chromatin
- A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity
- (2018) Evan M. Cornett et al. Science Advances
- RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation
- (2017) Scott M. Carlson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease
- (2017) Linda Xiaoyan Li et al. JOURNAL OF CLINICAL INVESTIGATION
- The methyltransferase NSD3 promotes antiviral innate immunity via direct lysine methylation of IRF3
- (2017) Chunmei Wang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The winding path of protein methylation research: milestones and new frontiers
- (2017) Jernej Murn et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- LSD1 demethylates HIF1α to inhibit hydroxylation and ubiquitin-mediated degradation in tumor angiogenesis
- (2017) J-Y Lee et al. ONCOGENE
- A simplified characterization of S-adenosyl-l-methionine-consuming enzymes with 1-Step EZ-MTase: a universal and straightforward coupled-assay for in vitro and in vivo setting
- (2017) Emmanuel S. Burgos et al. Chemical Science
- Peptide inhibition of the SETD6 methyltransferase catalytic activity
- (2017) Michal Feldman et al. Oncotarget
- Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress
- (2017) Palaniraja Thandapani et al. Oncotarget
- WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer
- (2017) Vassiliki Saloura et al. Scientific Reports
- Protein lysine methylation by seven- -strand methyltransferases
- (2016) P. O. Falnes et al. BIOCHEMICAL JOURNAL
- SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling
- (2016) Menno J. Oudhoff et al. DEVELOPMENTAL CELL
- RB1: a prototype tumor suppressor and an enigma
- (2016) Nicholas J. Dyson GENES & DEVELOPMENT
- PAK4 Methylation by SETD6 Promotes the Activation of the Wnt/β-Catenin Pathway
- (2016) Zlata Vershinin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Specificity of the SUV4–20H1 and SUV4–20H2 protein lysine methyltransferases and methylation of novel substrates
- (2016) Sara Weirich et al. JOURNAL OF MOLECULAR BIOLOGY
- G9a-mediated methylation of ERα links the PHF20/MOF histone acetyltransferase complex to hormonal gene expression
- (2016) Xi Zhang et al. Nature Communications
- Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis
- (2016) Yunho Kim et al. Nature Communications
- Nonhistone Lysine Methylation in the Regulation of Cancer Pathways
- (2016) Scott M. Carlson et al. Cold Spring Harbor Perspectives in Medicine
- Set7 mediated Gli3 methylation plays a positive role in the activation of Sonic Hedgehog pathway in mammals
- (2016) Lin Fu et al. eLife
- Methylation by Set9 modulates FoxO3 stability and transcriptional activity
- (2016) Daniel R. Calnan et al. Aging-US
- Chromatin associated SETD3 negatively regulates VEGF expression
- (2016) Ofir Cohn et al. Scientific Reports
- Emerging roles of lysine methylation on non-histone proteins
- (2015) Xi Zhang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- SET7/9 regulates cancer cell proliferation by influencing β-catenin stability
- (2015) Changchun Shen et al. FASEB JOURNAL
- A Proteomic Strategy Identifies Lysine Methylation of Splicing Factor snRNP70 by the SETMAR Enzyme
- (2015) Scott M. Carlson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
- (2015) Xing Liu et al. NUCLEIC ACIDS RESEARCH
- STAT3-driven transcription depends upon the dimethylation of K49 by EZH2
- (2015) Maupali Dasgupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discovery of Substrates for a SET Domain Lysine Methyltransferase Predicted by Multistate Computational Protein Design
- (2015) Sylvain Lanouette et al. STRUCTURE
- A continuous kinetic assay for protein and DNA methyltransferase enzymatic activities
- (2015) Shai Duchin et al. Epigenetics & Chromatin
- RB1 dual role in proliferation and apoptosis: cell fate control and implications for cancer therapy
- (2015) Paola Indovina et al. Oncotarget
- Investigation of the methylation of Numb by the SET8 protein lysine methyltransferase
- (2015) Sara Weirich et al. Scientific Reports
- RB1 Methylation by SMYD2 Enhances Cell Cycle Progression through an Increase of RB1 Phosphorylation
- (2015) Hyun-Soo Cho et al. NEOPLASIA
- Molecular basis for substrate recognition by lysine methyltransferases and demethylases
- (2014) Paul A. Del Rizzo et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- An unexpected journey: Lysine methylation across the proteome
- (2014) Kaitlyn E. Moore et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Methyllysine Reader Plant Homeodomain (PHD) Finger Protein 20-like 1 (PHF20L1) Antagonizes DNA (Cytosine-5) Methyltransferase 1 (DNMT1) Proteasomal Degradation
- (2014) Pierre-Olivier Estève et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Emerging Technologies to Map the Protein Methylome
- (2014) Scott M. Carlson et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Insights into Estrogen Receptor α Methylation by Histone Methyltransferase SMYD2, a Cellular Event Implicated in Estrogen Signaling Regulation
- (2014) Yuanyuan Jiang et al. JOURNAL OF MOLECULAR BIOLOGY
- The functional diversity of protein lysine methylation
- (2014) S. Lanouette et al. Molecular Systems Biology
- Non-histone protein methylation as a regulator of cellular signalling and function
- (2014) Kyle K. Biggar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- New concepts in DNA methylation
- (2014) Albert Jeltsch et al. TRENDS IN BIOCHEMICAL SCIENCES
- The Histone Methyltransferase SMYD2 Methylates PARP1 and Promotes Poly(ADP-ribosyl)ation Activity in Cancer Cells
- (2014) Lianhua Piao et al. NEOPLASIA
- Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
- (2013) Eunhee Kim et al. CANCER CELL
- Control of the Hippo Pathway by Set7-Dependent Methylation of Yap
- (2013) Menno J. Oudhoff et al. DEVELOPMENTAL CELL
- Large-scale global identification of protein lysine methylation in vivo
- (2013) Xing-Jun Cao et al. Epigenetics
- Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation
- (2013) S. B. Rothbart et al. GENES & DEVELOPMENT
- Transcriptional Properties of Mammalian Elongin A and Its Role in Stress Response
- (2013) Junya Kawauchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Immunoaffinity Enrichment and Mass Spectrometry Analysis of Protein Methylation
- (2013) Ailan Guo et al. MOLECULAR & CELLULAR PROTEOMICS
- A General Molecular Affinity Strategy for Global Detection and Proteomic Analysis of Lysine Methylation
- (2013) Kaitlyn E. Moore et al. MOLECULAR CELL
- A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response
- (2013) Huadong Liu et al. MOLECULAR CELL
- Dynamic Methylation of Numb by Set8 Regulates Its Binding to p53 and Apoptosis
- (2013) Gurpreet Kaur Dhami et al. MOLECULAR CELL
- Proteome-wide enrichment of proteins modified by lysine methylation
- (2013) Scott M Carlson et al. Nature Protocols
- Regulation of estrogen receptor by histone methyltransferase SMYD2-mediated protein methylation
- (2013) X. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation
- (2013) K. Islam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- SET7/9-dependent methylation of ARTD1 at K508 stimulates poly-ADP-ribose formation after oxidative stress
- (2013) I. Kassner et al. Open Biology
- An easy-to-perform photometric assay for methyltransferase activity measurements
- (2012) Till F. Schäberle et al. ANALYTICAL BIOCHEMISTRY
- Luciferase-Based Assay for Adenosine: Application to S-Adenosyl-l-homocysteine Hydrolase
- (2012) Emmanuel S. Burgos et al. ANALYTICAL CHEMISTRY
- Histone Lysine Methyltransferase SETD8 Promotes Carcinogenesis by Deregulating PCNA Expression
- (2012) M. Takawa et al. CANCER RESEARCH
- Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death
- (2012) Qi Xie et al. EMBO REPORTS
- PRC2 directly methylates GATA4 and represses its transcriptional activity
- (2012) A. He et al. GENES & DEVELOPMENT
- Bioorthogonal Profiling of Protein Methylation Using Azido Derivative of S-Adenosyl-l-methionine
- (2012) Kabirul Islam et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
- (2012) Joshua C. Black et al. MOLECULAR CELL
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- Histone methylation: a dynamic mark in health, disease and inheritance
- (2012) Eric L. Greer et al. NATURE REVIEWS GENETICS
- PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53
- (2012) Gaofeng Cui et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Diversity within the pRb pathway: is there a code of conduct?
- (2012) S Munro et al. ONCOGENE
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Characterizing DNA Methyltransferases With An Ultrasensitive Luciferase-Linked Continuous Assay
- (2011) Ivan Hemeon et al. ANALYTICAL CHEMISTRY
- Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase
- (2011) Arunkumar Dhayalan et al. CHEMISTRY & BIOLOGY
- Methylation-mediated regulation of E2F1 in DNA damage-induced cell death
- (2011) Qi Xie et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Lysine Methylation and Functional Modulation of Androgen Receptor by Set9 Methyltransferase
- (2011) Soyoung Ko et al. MOLECULAR ENDOCRINOLOGY
- Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling
- (2011) Yanqi Chang et al. NUCLEIC ACIDS RESEARCH
- A proteomic approach for the identification of novel lysine methyltransferase substrates
- (2011) Dan Levy et al. Epigenetics & Chromatin
- MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a
- (2011) Yanqi Chang et al. Nature Communications
- An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases
- (2010) Glorymar Ibáñez et al. ANALYTICAL BIOCHEMISTRY
- Enzymatic Site-Specific Functionalization of Protein Methyltransferase Substrates with Alkynes for Click Labeling
- (2010) Wibke Peters et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Identification of Protein N-Terminal Methyltransferases in Yeast and Humans
- (2010) Kristofor J. Webb et al. BIOCHEMISTRY
- Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells
- (2010) H.-S. Cho et al. CANCER RESEARCH
- A Chemical Method for Labeling Lysine Methyltransferase Substrates
- (2010) Olivier Binda et al. CHEMBIOCHEM
- Methylation of the Retinoblastoma Tumor Suppressor by SMYD2
- (2010) Louis A. Saddic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression
- (2010) Lisandra E. West et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G9a and Glp Methylate Lysine 373 in the Tumor Suppressor p53
- (2010) Jing Huang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
- (2010) Jason S. Lee et al. MOLECULAR CELL
- Lysine Methylation Regulates E2F1-Induced Cell Death
- (2010) Haroula Kontaki et al. MOLECULAR CELL
- Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
- (2010) Dan Levy et al. NATURE IMMUNOLOGY
- A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability
- (2010) Pierre-Olivier Estève et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Regulation of the androgen receptor by SET9-mediated methylation
- (2010) Luke Gaughan et al. NUCLEIC ACIDS RESEARCH
- Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes
- (2010) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PCNA on the crossroad of cancer
- (2009) Ivaylo Stoimenov et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit
- (2009) Xiao-Dong Yang et al. EMBO JOURNAL
- Regulation of NF-κB activity through lysine monomethylation of p65
- (2009) Chee-Kwee Ea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells
- (2009) P.-O. Esteve et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of NF- B by NSD1/FBXL11-dependent reversible lysine methylation of p65
- (2009) T. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone methyltransferases in cancer
- (2009) Mareike Albert et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Control of NF- B-dependent Transcriptional Responses by Chromatin Organization
- (2009) G. Natoli Cold Spring Harbor Perspectives in Biology
- Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins
- (2008) Philipp Rathert et al. Molecular BioSystems
- Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
- (2008) Krithika Subramanian et al. MOLECULAR CELL
- Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo
- (2008) Julia K. Kurash et al. MOLECULAR CELL
- Protein lysine methyltransferase G9a acts on non-histone targets
- (2008) Philipp Rathert et al. Nature Chemical Biology
- The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
- (2008) Jing Wang et al. NATURE GENETICS
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