Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis

Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation

(2015) Xing Liu et al.   NUCLEIC ACIDS RESEARCH

LSD1 sustains pancreatic cancer growth via maintaining HIF1α-dependent glycolytic process

(2014) Yi Qin et al.   CANCER LETTERS

Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer

(2013) Peter J. Ratcliffe   JOURNAL OF PHYSIOLOGY-LONDON

The lysine specific demethylase-1 (LSD1/KDM1A) regulates VEGF-A expression in prostate cancer

(2013) Vasundhra Kashyap et al.   Molecular Oncology

Integrated genomic characterization of endometrial carcinoma

(2013) Gad Getz et al.   NATURE

Titivated for Destruction: The Methyl Degron

(2012) Yanzhong Yang et al.   MOLECULAR CELL

EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex

(2012) Ji Min Lee et al.   MOLECULAR CELL

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The HIF Pathway and Erythrocytosis

(2011) Frank S. Lee et al.   Annual Review of Pathology-Mechanisms of Disease

Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

(2011) Arunkumar Dhayalan et al.   CHEMISTRY & BIOLOGY

The Methyltransferase Set7/9 (Setd7) Is Dispensable for the p53-Mediated DNA Damage Response In Vivo

(2011) Stefano Campaner et al.   MOLECULAR CELL

Oxygen Sensing, Homeostasis, and Disease

(2011) Gregg L. Semenza   NEW ENGLAND JOURNAL OF MEDICINE

Genetic and Functional Studies Implicate HIF1  as a 14q Kidney Cancer Suppressor Gene

(2011) C. Shen et al.   Cancer Discovery

Methylation, a new epigenetic mark for protein stability

(2010) Xiao-Dong Yang et al.   Epigenetics

Hypoxia-mediated biological control

(2010) Jessica Cassavaugh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Lysine Methylation Regulates E2F1-Induced Cell Death

(2010) Haroula Kontaki et al.   MOLECULAR CELL

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

(2010) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy

(2009) J. H. Schulte et al.   CANCER RESEARCH

Lysine-specific demethylase 1 (LSD1) is highly expressed in ER-negative breast cancers and a biomarker predicting aggressive biology

(2009) Soyoung Lim et al.   CARCINOGENESIS

Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis

(2009) Kip M Connor et al.   Nature Protocols

Generating specificity and diversity in the transcriptional response to hypoxia

(2009) Urban Lendahl et al.   NATURE REVIEWS GENETICS

Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells

(2009) P.-O. Esteve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical Characterization of Human Prolyl Hydroxylase Domain Protein 2 Variants Associated with Erythrocytosis

(2008) Melissa B. Pappalardi et al.   BIOCHEMISTRY

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

(2008) Julia K. Kurash et al.   MOLECULAR CELL

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

(2008) Jing Wang et al.   NATURE GENETICS

Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

(2007) K. Takeda et al.   BLOOD