Matrix metalloproteinases and ADAMs in stroke

Detection of plasma MMP-9 within minutes. Unveiling some of the clues to develop fast and simple electrochemical magneto-immunosensors

(2018) Gisela Ruiz-Vega et al.   BIOSENSORS & BIOELECTRONICS

Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association

(2018) Emelia J. Benjamin et al.   CIRCULATION

Biomarkers identify the Binswanger type of vascular cognitive impairment

(2018) Erik Barry Erhardt et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Accuracy of Serum Matrix Metalloproteinase-9 for Predicting Hemorrhagic Transformation After Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

(2018) Lu Wang et al.   Journal of Stroke & Cerebrovascular Diseases

OUP accepted manuscript

(2018)   NEPHROLOGY DIALYSIS TRANSPLANTATION

MMP-9 and/or TIMP as predictors of ischaemic stroke in patients with symptomatic and asymptomatic atherosclerotic stenosis of carotid artery treated by stenting or endarterectomy – A review

(2018) Justyna Zielinska-Turek et al.   Neurologia i Neurochirurgia Polska

Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct

(2018) Raul G. Nogueira et al.   NEW ENGLAND JOURNAL OF MEDICINE

Advances in Stroke 2017

(2018) Julie Bernhardt et al.   STROKE

High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage

(2018) Martin Söderholm et al.   STROKE

STARTING-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Intravenous Thrombolysis for Stroke

(2018) Manuel Cappellari et al.   STROKE

Small Vessel Disease Is Associated with Tissue Inhibitor of Matrix Metalloproteinase-4 After Ischaemic Stroke

(2018) Francesco Arba et al.   Translational Stroke Research

Serum Matrix Metalloproteinase‐9 and Cognitive Impairment After Acute Ischemic Stroke

(2018) Chongke Zhong et al.   Journal of the American Heart Association

The Accuracy of Serum Matrix Metalloproteinase-9 for Predicting Hemorrhagic Transformation After Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

(2018) Lu Wang et al.   Journal of Stroke & Cerebrovascular Diseases

The Role of von Willebrand Factor, ADAMTS13, and Cerebral Artery Thrombus Composition in Patient Outcome Following Mechanical Thrombectomy for Acute Ischemic Stroke

(2018) Vaclav Prochazka et al.   MEDICAL SCIENCE MONITOR

The Extracellular Environment of the CNS: Influence on Plasticity, Sprouting, and Axonal Regeneration after Spinal Cord Injury

(2018) Shmma Quraishe et al.   NEURAL PLASTICITY

Revascularization and Endothelial Progenitor Cells in Stroke

(2018) Gema Esquiva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Serum Markers of Blood-Brain Barrier Remodeling and Fibrosis as Predictors of Etiology and Clinicoradiologic Outcome in Intracerebral Hemorrhage

(2018) Matthew D. Howe et al.   Frontiers in Neurology

Inflammatory and metalloproteinases profiles predict three-month poor outcomes in ischemic stroke treated with thrombolysis

(2017) Anna Maria Gori et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Postischemic Inflammation in Acute Stroke

(2017) Simone Vidale et al.   Journal of Clinical Neurology

Neutrophil Infiltration and Matrix Metalloproteinase-9 in Lacunar Infarction

(2017) Wolfgang Walz et al.   NEUROCHEMICAL RESEARCH

Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke

(2017) Chongke Zhong et al.   NEUROLOGY

Blood Biomarkers for the Early Diagnosis of Stroke

(2017) Alejandro Bustamante et al.   STROKE

Plasma ADAMTS13 activity and von Willebrand factor antigen and activity in patients with subarachnoid haemorrhage

(2017) Jenny K. McDaniel et al.   THROMBOSIS AND HAEMOSTASIS

Biomarkers of Atrial Fibrillation in Hypertension

(2017) Costas Tsioufis et al.   CURRENT MEDICINAL CHEMISTRY

Plasma Matrix Metalloproteinases in Patients With Stroke During Intensive Rehabilitation Therapy

(2016) Feifei Ma et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Matrix Metalloproteinase-Mediated Neuroinflammation in Vascular Cognitive Impairment of the Binswanger Type

(2016) Gary A. Rosenberg   CELLULAR AND MOLECULAR NEUROBIOLOGY

Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke

(2016) Sighild Lemarchant et al.   GLIA

Blood biomarkers associated with neurological deterioration in patients with acute penetrating artery territory infarction: A multicenter prospective observational study

(2016) Tomohiro Kawano et al.   International Journal of Stroke

Matrix metalloproteinase-13 participates in neuroprotection and neurorepair after cerebral ischemia in mice

(2016) Feifei Ma et al.   NEUROBIOLOGY OF DISEASE

Tissue Plasminogen Activator Neurotoxicity is Neutralized by Recombinant ADAMTS 13

(2016) Mengchen Fan et al.   Scientific Reports

A score including ADAM17 substrates correlates to recurring cardiovascular event in subjects with atherosclerosis

(2015) Stefano Rizza et al.   ATHEROSCLEROSIS

Low ADAMTS13 activity is associated with an increased risk of ischemic stroke

(2015) M. A. H. Sonneveld et al.   BLOOD

Matrix metalloproteinases as therapeutic targets for stroke

(2015) Yi Yang et al.   BRAIN RESEARCH

Assessment of the Diagnostic Value of Plasma Levels, Activities, and Their Ratios of von Willebrand Factor and ADAMTS13 in Patients with Cerebral Infarction

(2015) Le Qu et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Protective Role for Tissue Inhibitor of Metalloproteinase-4, a Novel Peroxisome Proliferator–Activated Receptor-γ Target Gene, in Smooth Muscle in Deoxycorticosterone Acetate–Salt HypertensionNovelty and Significance

(2015) Pimonrat Ketsawatsomkron et al.   HYPERTENSION

Impaired Vascular Remodeling after Endothelial Progenitor Cell Transplantation in MMP9-Deficient Mice Suffering Cortical Cerebral Ischemia

(2015) Anna Morancho et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood and CSF biomarkers in brain subcortical ischemic vascular disease: Involved pathways and clinical applicability

(2015) A Vilar-Bergua et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Proteomic Signature of Endothelial Dysfunction Identified in the Serum of Acute Ischemic Stroke Patients by the iTRAQ-Based LC–MS Approach

(2015) Rakesh Sharma et al.   JOURNAL OF PROTEOME RESEARCH

Relationship between ADAMTS13 activity, von Willebrand factor antigen levels and platelet function in the early and late phases after TIA or ischaemic stroke

(2015) Dominick J.H. McCabe et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

ADAMTS expression and function in central nervous system injury and disorders

(2015) Paul E. Gottschall et al.   MATRIX BIOLOGY

Matrix metalloproteinase 9–mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy

(2015) Lingzhi Zhao et al.   NEUROBIOLOGY OF AGING

Recombinant ADAMTS 13 Attenuates Brain Injury After Intracerebral Hemorrhage

(2015) Ping Cai et al.   STROKE

Mechanical Thrombectomy in and Outside the REVASCAT Trial

(2015) Xabier Urra et al.   STROKE

Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip

(2015) Lars Lind et al.   STROKE

Matrix Metalloproteinase-12 Induces Blood–Brain Barrier Damage After Focal Cerebral Ischemia

(2015) Bharath Chelluboina et al.   STROKE

Unbalanced Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinases Ratios Predict Hemorrhagic Transformation of Lesion in Ischemic Stroke Patients Treated with Thrombolysis: Results from the MAGIC Study

(2015) Benedetta Piccardi et al.   Frontiers in Neurology

Association of MMP-9 Haplotypes and TIMP-1 Polymorphism with Spontaneous Deep Intracerebral Hemorrhage in the Taiwan Population

(2015) Wei-Min Ho et al.   PLoS One

Polymorphisms in the Promoters of the MMP-2 and TIMP-2 Genes Are Associated with Spontaneous Deep Intracerebral Hemorrhage in the Taiwan Population

(2015) Yi Chun Chen et al.   PLoS One

Matrix Metalloproteinase 7 Is Associated with Symptomatic Lesions and Adverse Events in Patients with Carotid Atherosclerosis

(2014) Azhar Abbas et al.   PLoS One

Role of Matrix Metalloproteinases in Migration and Neurotrophic Properties of Nasal Olfactory Stem and Ensheathing Cells

(2013) Adlane Ould-Yahoui et al.   CELL TRANSPLANTATION

TIMP-1 polymorphisms in a Chinese Han population with intracerebral hemorrhage

(2013) Hong-Xing Wang et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Cerebral ischaemia and matrix metalloproteinase-9 modulate the angiogenic function of early and late outgrowth endothelial progenitor cells

(2013) Anna Morancho et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Changes in platelet GPIbα and ADAM17 during the acute stage of atherosclerotic ischemic stroke among Chinese

(2013) Jia-yan Ling et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

ADAMTS proteoglycanases in the physiological and pathological central nervous system

(2013) Sighild Lemarchant et al.   Journal of Neuroinflammation

A Blood-based Biomarker Panel to Detect Acute Stroke

(2013) Richa Sharma et al.   Journal of Stroke & Cerebrovascular Diseases

proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke

(2013) J. A. Rodríguez et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

Differential Regulation of Matrix-Metalloproteinases and Their Tissue Inhibitors in Patients with Aneurysmal Subarachnoid Hemorrhage

(2013) Marlene Fischer et al.   PLoS One

Factors Secreted by Endothelial Progenitor Cells Enhance Neurorepair Responses after Cerebral Ischemia in Mice

(2013) Anna Rosell et al.   PLoS One

Association of Molecular Markers With Perihematomal Edema and Clinical Outcome in Intracerebral Hemorrhage

(2013) Na Li et al.   STROKE

ADAM17 is a survival factor for microglial cells in vitro and in vivo after spinal cord injury in mice

(2013) P M Vidal et al.   Cell Death & Disease

Recombinant ADAMTS13 reduces tissue plasminogen activator-induced hemorrhage after stroke in mice

(2012) Lixiang Wang et al.   ANNALS OF NEUROLOGY

Matrix Metalloproteinases in Human Spontaneous Intracerebral Hemorrhage: An Update

(2012) M. Florczak-Rzepka et al.   CEREBROVASCULAR DISEASES

Inhibition of MMP-9 Activity following Hypoxic Ischemia in the Developing Brain Using a Highly Specific Inhibitor

(2012) Himani S. Ranasinghe et al.   DEVELOPMENTAL NEUROSCIENCE

Melatonin reduced the elevated matrix metalloproteinase-9 level in a rat photothrombotic stroke model

(2012) Jae-Won Jang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia

(2012) Jiankun Cui et al.   Molecular Neurodegeneration

ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia–reperfusion injury

(2012) Masayuki Fujioka et al.   NEUROLOGICAL SCIENCES

A broad-spectrum matrix metalloproteinase inhibitor prevents hemorrhagic complications induced by tissue plasminogen activator in mice

(2012) K. Mishiro et al.   NEUROSCIENCE

MMP-2/MMP-9 Plasma Level and Brain Expression in Cerebral Amyloid Angiopathy-Associated Hemorrhagic Stroke

(2011) Mar Hernandez-Guillamon et al.   BRAIN PATHOLOGY

Collagenase matrix metalloproteinase-8 expressed in atherosclerotic carotid plaques is associated with systemic cardiovascular outcome

(2011) Wouter Peeters et al.   EUROPEAN HEART JOURNAL

The Potential Role of Metalloproteinases in Neurogenesis in the Gerbil Hippocampus Following Global Forebrain Ischemia

(2011) Luiza Wójcik-Stanaszek et al.   PLoS One

Matrix Metalloproteinase-9 in an Exploratory Trial of Intravenous Minocycline for Acute Ischemic Stroke

(2011) Jeffrey A. Switzer et al.   STROKE

Matrix Metalloproteinases Are Associated With Increased Blood–Brain Barrier Opening in Vascular Cognitive Impairment

(2011) Eduardo Candelario-Jalil et al.   STROKE

The Temporal Profile of Inflammatory Markers and Mediators in Blood after Acute Ischemic Stroke Differs Depending on Stroke Outcome

(2010) H. Worthmann et al.   CEREBROVASCULAR DISEASES

Matrix Metalloproteinase 2 (MMP-2) Degrades Soluble Vasculotropic Amyloid-β E22Q and L34V Mutants, Delaying Their Toxicity for Human Brain Microvascular Endothelial Cells

(2010) Mar Hernandez-Guillamon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A panel of biomarkers including caspase-3 and D-dimer may differentiate acute stroke from stroke-mimicking conditions in the emergency department

(2010) J. Montaner et al.   JOURNAL OF INTERNAL MEDICINE

Role of Tissue-Type Plasminogen Activator in Ischemic Stroke

(2010) Yasuhiro Suzuki   JOURNAL OF PHARMACOLOGICAL SCIENCES

Transplanted Late Outgrowth Endothelial Progenitor Cells as Cell Therapy Product for Stroke

(2010) Chahrazad Moubarik et al.   Stem Cell Reviews and Reports

Minocycline to Improve Neurologic Outcome in Stroke (MINOS)

(2010) Susan C. Fagan et al.   STROKE

Matrix Metalloproteinase-9 Is Essential for Ischemia-Induced Neovascularization by Modulating Bone Marrow–Derived Endothelial Progenitor Cells

(2009) Po-Hsun Huang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke

(2009) Z. Li et al.   BLOOD

von Willebrand factor-cleaving protease ADAMTS13 reduces ischemic brain injury in experimental stroke

(2009) B.-Q. Zhao et al.   BLOOD

Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases

(2009) Rory R. Koenen et al.   BLOOD

TIMP-2 Gene Polymorphism Is Associated with Intracerebral Hemorrhage

(2009) Bjoern Reuter et al.   CEREBROVASCULAR DISEASES

The role of dynamic contrast enhanced MRI in the detection of recurrent prostate carcinoma after external beam radiotherapy-correlation with transrectal ultrasound and pathological findings

(2009) Taylan Kara et al.   Diagnostic and Interventional Radiology

Atorvastatin Extends the Therapeutic Window for tPA to 6 h after the Onset of Embolic Stroke in Rats

(2009) Li Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Neuroprotective Effects of Overexpressing Tissue Inhibitor of Metalloproteinase TIMP-1

(2009) Emiri Tejima et al.   JOURNAL OF NEUROTRAUMA

Vascular MMP-9/TIMP-2 and Neuronal MMP-10 Up-Regulation in Human Brain after Stroke: A Combined Laser Microdissection and Protein Array Study

(2009) Eloy Cuadrado et al.   JOURNAL OF PROTEOME RESEARCH

ADAMTS-9 expression is up-regulated following transient middle cerebral artery occlusion (tMCAo) in the rat

(2009) Martin J. Reid et al.   NEUROSCIENCE LETTERS

Plasma and Brain Matrix Metalloproteinase-9 After Acute Focal Cerebral Ischemia in Rats

(2009) Kyung-Pil Park et al.   STROKE

Contributions of multiple proteases to neurotoxicity in a mouse model of intracerebral haemorrhage

(2008) Mengzhou Xue et al.   BRAIN

Maraviroc:in vitroassessment of drug-drug interaction potential

(2008) Ruth Hyland et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Multiphasic roles for matrix metalloproteinases after stroke

(2008) A ROSELL et al.   CURRENT OPINION IN PHARMACOLOGY

Delayed matrix metalloproteinase inhibition reduces intracerebral hemorrhage after embolic stroke in rats

(2008) Jean-Christophe Copin et al.   EXPERIMENTAL NEUROLOGY

Matrix Metalloproteinase-13 is Activated and is found in the Nucleus of Neural Cells after Cerebral Ischemia

(2008) Eloy Cuadrado et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

ADAMTS13: a new link between thrombosis and inflammation

(2008) Anil K. Chauhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tissue plasminogen activator (t-PA) promotes neutrophil degranulation and MMP-9 release

(2008) Eloy Cuadrado et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A new penumbra: transitioning from injury into repair after stroke

(2008) Eng H Lo   NATURE MEDICINE

Endogenous Matrix Metalloproteinase (MMP)-3 and MMP-9 Promote the Differentiation and Migration of Adult Neural Progenitor Cells in Response to Chemokines

(2008) Basam Z. Barkho et al.   STEM CELLS

Extension of the Thrombolytic Time Window With Minocycline in Experimental Stroke

(2008) Yoshihiro Murata et al.   STROKE

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE

Multimodal signaling by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs) promotes neurite extension

(2007) Michelle G. Hamel et al.   EXPERIMENTAL NEUROLOGY