Crosstalk between chitosan and cell signaling pathways

New therapeutic activity of metabolic enhancer piracetam in treatment of neurodegenerative disease: Participation of caspase independent death factors, oxidative stress, inflammatory responses and apoptosis

(2018) Dinesh Kumar Verma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

3D Protein-Based Bilayer Artificial Skin for the Guided Scarless Healing of Third-Degree Burn Wounds in Vivo

(2018) Mazaher Gholipourmalekabadi et al.   BIOMACROMOLECULES

Migration and Contraction of Fibroblasts from Normal and Scar Vocal Folds with Applications to Wound Healing

(2018) Anete Branco et al.   BIOPHYSICAL JOURNAL

Sulfite protects neurons from oxidative stress

(2018) Yuka Kimura et al.   BRITISH JOURNAL OF PHARMACOLOGY

A systematic approach of chitosan nanoparticle preparation via emulsion crosslinking as potential adsorbent in wastewater treatment

(2018) Benjamin R. Riegger et al.   CARBOHYDRATE POLYMERS

Systemic Delivery of Free Chitosan Accelerates Femur Fracture Healing in Rats

(2018) Peng Shao et al.   CURRENT DRUG TARGETS

Oxidative stress caused by accumulation of misfolded Z-type alpha1-antitrypsin

(2018) Hana Im et al.   FREE RADICAL BIOLOGY AND MEDICINE

Novel 1,4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells

(2018) Chang Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Organically modified clay supported chitosan/hydroxyapatite-zinc oxide nanocomposites with enhanced mechanical and biological properties for the application in bone tissue engineering

(2018) Arundhati Bhowmick et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitin and chitosan preparation from shrimp shells Penaeus monodon and its human ovarian cancer cell line, PA-1

(2018) Haripriya Srinivasan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

A review on chitosan and its nanocomposites in drug delivery

(2018) Akbar Ali et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitosan-film associated with mesenchymal stem cells enhanced regeneration of peripheral nerves: A rat sciatic nerve model

(2018) Mehrnaz Moattari et al.   JOURNAL OF CHEMICAL NEUROANATOMY

The interplay between AR, EGF receptor and MMP-9 signaling pathways in invasive prostate cancer

(2018) Anna Mandel et al.   MOLECULAR MEDICINE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Comparision between human amniotic fluid and adipous tissue mesenchymal stem cells induced-chondrogenesis cultured in chitosan-xanthan scaffold stimulated with TGF-β3

(2018) I.I. Damas et al.   OSTEOARTHRITIS AND CARTILAGE

Recent advances in chitosan-based self-healing materials

(2018) Fuyuan Ding et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Application of Chitin/Chitosan and Their Derivatives in the Papermaking Industry

(2018) et al.   Polymers

Graphene oxide as a dual Zn/Mg ion carrier and release platform: enhanced osteogenic activity and antibacterial properties

(2018) Jiajun Qiu et al.   Journal of Materials Chemistry B

Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease

(2018) Yen Ying Lim et al.   JAMA Neurology

Ionic liquids in the processing and chemical modification of chitin and chitosan for biomedical applications

(2017) Simone S. Silva et al.   GREEN CHEMISTRY

Chitosan/TiO 2 composite membrane improves proliferation and survival of L929 fibroblast cells: Application in wound dressing and skin regeneration

(2017) Sudhanshu Shekhar Behera et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Interaction of chitin/chitosan with salivary and other epithelial cells—An overview

(2017) Sharvari Vijaykumar Patil et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Overviews on the cellular uptake mechanism of polysaccharide colloidal nanoparticles

(2017) Sara Salatin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

An Overview of the Protective Effects of Chitosan and Acetylated Chitosan Oligosaccharides against Neuronal Disorders

(2017) Cui Hao et al.   Marine Drugs

The effect of PEGylated hollow gold nanoparticles on stem cell migration: potential application in tissue regeneration

(2017) Maria del Mar Encabo-Berzosa et al.   Nanoscale

p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection

(2017) Manoj B. Menon et al.   NATURE CELL BIOLOGY

Chitosan for wastewater treatment

(2017) Jacques Desbrières et al.   POLYMER INTERNATIONAL

Effects of Chitosan on the Secretion of Cytokines and Expression of Inducible Nitric Oxide Synthase mRNA in Peritoneal Macrophages of Broiler Chicken

(2017) Huiying Li et al.   BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY

Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing

(2016) V. Patrulea et al.   CARBOHYDRATE POLYMERS

Chitosan attenuates dibutyltin-induced apoptosis in PC12 cells through inhibition of the mitochondria-dependent pathway

(2016) Xiaorui Wang et al.   CARBOHYDRATE POLYMERS

Antimicrobial and antitumor activities of chitosan from shiitake stipes, compared to commercial chitosan from crab shells

(2016) Rao-Chi Chien et al.   CARBOHYDRATE POLYMERS

Decellularized human amniotic membrane: how viable is it as a delivery system for human adipose tissue-derived stromal cells?

(2016) M. Gholipourmalekabadi et al.   CELL PROLIFERATION

Chitosan oligosaccharides inhibit IL-1β-induced chondrocyte apoptosis via the P38 MAPK signaling pathway

(2016) Chun Zhang et al.   GLYCOCONJUGATE JOURNAL

Cytotoxicity of chitosans with different acetylation degrees and molecular weights on bladder carcinoma cells

(2016) Islem Younes et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Antitumor Effects of Orally and Intraperitoneally Administered Chitosan Oligosaccharides (COSs) on S180-Bearing/Residual Mouse

(2016) Pan Zou et al.   JOURNAL OF FOOD SCIENCE

Chitosan promotes aquaporin formation and inhibits mucociliary differentiation of nasal epithelial cells through increased TGF-β1 production

(2016) Tsung-Wei Huang et al.   Journal of Tissue Engineering and Regenerative Medicine

Oxygen-Generating Biomaterials: A New, Viable Paradigm for Tissue Engineering?

(2016) Mazaher Gholipourmalekabadi et al.   TRENDS IN BIOTECHNOLOGY

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

Activation of AMPK by chitosan oligosaccharide in intestinal epithelial cells: Mechanism of action and potential applications in intestinal disorders

(2015) Chatchai Muanprasat et al.   BIOCHEMICAL PHARMACOLOGY

Optimization of nanofibrous silk fibroin scaffold as a delivery system for bone marrow adherent cells:in vitroandin vivostudies

(2015) Mazaher Gholipourmalekabadi et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

The cell factory approach toward biotechnological production of high-value chitosan oligomers and their derivatives: an update

(2015) Shoa Naqvi et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Chitosan as a starting material for wound healing applications

(2015) V. Patrulea et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Chitosan oligosaccharides prevented retinal ischemia and reperfusion injury via reduced oxidative stress and inflammation in rats

(2015) I-Mo Fang et al.   EXPERIMENTAL EYE RESEARCH

Chitosan molecular weight effect on starch-composite film properties

(2015) María Julieta Bof et al.   FOOD HYDROCOLLOIDS

Chitosan Oligosaccharides Inhibit/Disaggregate Fibrils and Attenuate Amyloid β-Mediated Neurotoxicity

(2015) Xueling Dai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Review of Cell Adhesion Studies for Biomedical and Biological Applications

(2015) Amelia Khalili et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acetylated Chitosan Oligosaccharides Act as Antagonists against Glutamate-Induced PC12 Cell Death via Bcl-2/Bax Signal Pathway

(2015) Cui Hao et al.   Marine Drugs

Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

(2015) Randy Cheung et al.   Marine Drugs

Chitosan as an adjuvant for a Helicobacter pylori therapeutic vaccine

(2015) YANFENG GONG et al.   Molecular Medicine Reports

Synergistic effect of nanomaterials and BMP-2 signalling in inducing osteogenic differentiation of adipose tissue-derived mesenchymal stem cells

(2015) ZuFu Lu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Structural, phenotypic and functional maturation of bone marrow dendritic cells (BMDCs) induced by Chitosan (CTS)

(2014) Lihui Jia et al.   BIOLOGICALS

The potential role of free chitosan in bone trauma and bone cancer management

(2014) Mei L. Tan et al.   BIOMATERIALS

Anti-tumor properties of orally administered glucosamine and N-acetyl-d-glucosamine oligomers in a mouse model

(2014) Sachie Masuda et al.   CARBOHYDRATE POLYMERS

3D Porous Chitosan Scaffolds Suit Survival and Neural Differentiation of Dental Pulp Stem Cells

(2014) Xingmei Feng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Toll like receptor 4 (TLR4) mediates the stimulating activities of chitosan oligosaccharide on macrophages

(2014) Pei Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chitin extraction from shrimp shell using enzymatic treatment. Antitumor, antioxidant and antimicrobial activities of chitosan

(2014) Islem Younes et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

TLR-2 and IL-17A in Chitin-Induced Macrophage Activation and Acute Inflammation

(2014) C. A. Da Silva et al.   JOURNAL OF IMMUNOLOGY

Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-β1 and TGF-β2-dependent pathway

(2014) Ignacio Montorfano et al.   LABORATORY INVESTIGATION

Inhibitory effects of oligochitosan on TNF-α, IL-1β and nitric oxide production in lipopolysaccharide-induced RAW264.7 cells

(2014) JIE ZHU et al.   Molecular Medicine Reports

Flexible, micro-porous chitosan–gelatin hydrogel/nanofibrin composite bandages for treating burn wounds

(2014) P. T. Sudheesh Kumar et al.   RSC Advances

Chitosan exerts anticancer activity through induction of apoptosis and cell cycle arrest in oral cancer cells

(2014) Yuniardini S. Wimardhani et al.   Journal of Oral Science

Controlling branching structure formation of the salivary gland by the degree of chitosan deacetylation

(2013) Ya-Chuan Hsiao et al.   Acta Biomaterialia

Antibacterial Mechanism of Chitosan and its Applications in Protection of Plant from Bacterial Disease

(2013)   ASIAN JOURNAL OF CHEMISTRY

The localisation of inflammatory cells and expression of associated proteoglycans in response to implanted chitosan

(2013) Brooke L. Farrugia et al.   BIOMATERIALS

Chitosan stabilizes platelet growth factors and modulates stem cell differentiation toward tissue regeneration

(2013) Alberto Busilacchi et al.   CARBOHYDRATE POLYMERS

Immunomodulation of macrophages by methylglyoxal conjugated with chitosan nanoparticles against Sarcoma-180 tumor in mice

(2013) Adrita Chakrabarti et al.   CELLULAR IMMUNOLOGY

Efficient siRNA delivery and tumor accumulation mediated by ionically cross-linked folic acid–poly(ethylene glycol)–chitosan oligosaccharide lactate nanoparticles: For the potential targeted ovarian cancer gene therapy

(2013) Tony Shing Chau Li et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chitosan-based biomaterials for tissue engineering

(2013) Florence Croisier et al.   EUROPEAN POLYMER JOURNAL

Inflammation in neurodegenerative diseases - an update

(2013) Sandra Amor et al.   IMMUNOLOGY

Chitosan oligosaccharides downregulate the expression of E-selectin and ICAM-1 induced by LPS in endothelial cells by inhibiting MAP kinase signaling

(2013) YU LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Chitosan nanoparticles: Preparation, size evolution and stability

(2013) Antonio Rampino et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Low Molecular Weight Chitosan Accelerates Glucagon-like Peptide-1 Secretion in Human Intestinal Endocrine Cells via a p38-Dependent Pathway

(2013) Shing Hwa Liu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Effect of cell culture using chitosan membranes on stemness marker genes in mesenchymal stem cells

(2013) ZHIQIANG LI et al.   Molecular Medicine Reports

Chitosan Oligosaccharides Attenuates Oxidative-Stress Related Retinal Degeneration in Rats

(2013) I-Mo Fang et al.   PLoS One

Challenges and Opportunities for Tissue-Engineering Polarized Epithelium

(2013) Ana C. Paz et al.   TISSUE ENGINEERING PART B-REVIEWS

Nitric oxide compounds have different effects profiles on human articular chondrocyte metabolism

(2013) María C de Andrés et al.   ARTHRITIS RESEARCH & THERAPY

The influence of chitosan hydrogel on stem cell engraftment, survival and homing in the ischemic myocardial microenvironment

(2012) Zhiqiang Liu et al.   BIOMATERIALS

Anti-metastatic and anti-angiogenic activities of sulfated polysaccharide of Sepiella maindroni ink

(2012) Aizhen Zong et al.   CARBOHYDRATE POLYMERS

Sulfated chitooligosaccharide II (SCOS II) suppress collagen degradation in TNF-induced chondrosarcoma cells via NF-κB pathway

(2012) BoMi Ryu et al.   CARBOHYDRATE RESEARCH

The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses

(2012) Andres Mori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chitosan-based drug delivery systems

(2012) Andreas Bernkop-Schnürch et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Effective antitumor gene therapy delivered by polyethylenimine-conjugated stearic acid-g-chitosan oligosaccharide micelles

(2012) F-Q Hu et al.   GENE THERAPY

Chitosan oligosaccharides suppress production of nitric oxide in lipopolysaccharide-induced N9 murine microglial cells in vitro

(2012) Peng Wei et al.   GLYCOCONJUGATE JOURNAL

Chitosan oligosaccharide–arachidic acid-based nanoparticles for anti-cancer drug delivery

(2012) Ubonvan Termsarasab et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

In vitroantitumour activity of stearic acid-g-chitosan oligosaccharide polymeric micelles loading podophyllotoxin

(2012) Xuan Huang et al.   JOURNAL OF MICROENCAPSULATION

Chitosan Biomaterials Induce Branching Morphogenesis in a Model of Tissue-Engineered Glandular Organs in Serum-Free Conditions

(2012) Tsung-Lin Yang et al.   TISSUE ENGINEERING PART A

Chitosan oligosaccharides suppress LPS-induced IL-8 expression in human umbilical vein endothelial cells through blockade of p38 and Akt protein kinases

(2011) Hong-tao Liu et al.   ACTA PHARMACOLOGICA SINICA

The modulation of platelet adhesion and activation by chitosan through plasma and extracellular matrix proteins

(2011) Megan S. Lord et al.   BIOMATERIALS

Synthesis, characterization and biological safety of O-carboxymethyl chitosan used to treat Sarcoma 180 tumor

(2011) Meiling Zheng et al.   CARBOHYDRATE POLYMERS

Attenuation of pro-inflammatory mediators in LPS-stimulated BV2 microglia by chitooligosaccharides via the MAPK signaling pathway

(2011) Ratih Pangestuti et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Effects of the Molecular Weight and the Degree of Deacetylation of Chitosan Oligosaccharides on Antitumor Activity

(2011) Jae Kweon Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chitosan but Not Chitin Activates the Inflammasome by a Mechanism Dependent upon Phagocytosis

(2011) Chelsea L. Bueter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proliferation of Mesenchymal Stem Cell on Chitosan Films Associated with Convex Micro-topography

(2011) Julin Yang et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Chitosan Nanoparticles Act as an Adjuvant to Promote both Th1 and Th2 Immune Responses Induced by Ovalbumin in Mice

(2011) Zheng-Shun Wen et al.   Marine Drugs

Protective effect of chitosan oligosaccharides against FcɛRI-mediated RBL-2H3 mast cell activation

(2011) Thanh-Sang Vo et al.   PROCESS BIOCHEMISTRY

The role of mast cells in allergic inflammation

(2011) Kawa Amin   RESPIRATORY MEDICINE

Photocrosslinkable chitosan based hydrogels for neural tissue engineering

(2011) Chandra M. Valmikinathan et al.   Soft Matter

Chitooligosaccharides protect rat cortical neurons against copper induced damage by attenuating intracellular level of reactive oxygen species

(2010) Wei Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth

(2010) Serif Senturk et al.   HEPATOLOGY

Signaling networks in RUNX2-dependent bone development

(2010) Toshihisa Komori   JOURNAL OF CELLULAR BIOCHEMISTRY

Chitosan Modification and Pharmaceutical/Biomedical Applications

(2010) Jiali Zhang et al.   Marine Drugs

Molecular-Weight-Dependent Toxic Effects of Chitosans on the Human Keratinocyte Cell Line HaCaT

(2010) C. Wiegand et al.   SKIN PHARMACOLOGY AND PHYSIOLOGY

Effect of chitosan scaffold microstructure on mesenchymal stem cell chondrogenesis

(2009) Guillaume R. Ragetly et al.   Acta Biomaterialia

Simple Agarose−Chitosan Gel Composite System for Enhanced Neuronal Growth in Three Dimensions

(2009) Zheng Cao et al.   BIOMACROMOLECULES

Inhibitory effects of chitooligosaccharides on tumor growth and metastasis

(2009) Kun-Te Shen et al.   FOOD AND CHEMICAL TOXICOLOGY

Runx2-mediatedbcl-2gene expression contributes to nitric oxide protection against hydrogen peroxide-induced osteoblast apoptosis

(2009) Wei-Pin Ho et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chitosan prevents oxidative stress-induced amyloid β formation and cytotoxicity in NT2 neurons: involvement of transcription factors Nrf2 and NF-κB

(2009) Fariba Khodagholi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

A review of the antimicrobial activity of chitosan

(2009) Rejane C. Goy et al.   Polimeros-Ciencia e Tecnologia

Neutrophils exhibit distinct phenotypes toward chitosans with different degrees of deacetylation: implications for cartilage repair

(2009) Pascale Simard et al.   ARTHRITIS RESEARCH & THERAPY

The Mechanical and Biological Properties of Chitosan Scaffolds for Tissue Regeneration Templates Are Significantly Enhanced by Chitosan from Gongronella butleri

(2009) Nitar Nwe et al.   Materials

The effect of chitosan on the migration of neutrophil-like HL60 cells, mediated by IL-8

(2008) Chan J. Park et al.   BIOMATERIALS

Stress fracture healing: Fatigue loading of the rat ulna induces upregulation in expression of osteogenic and angiogenic genes that mimic the intramembranous portion of fracture repair

(2008) Gregory R. Wohl et al.   BONE

The effect of hyaluronic acid on IL-1β-induced chondrocyte apoptosis in a rat model of osteoarthritis

(2008) Pang-Hu Zhou et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The Interleukin 1β Pathway in the Pathogenesis of Osteoarthritis

(2008) Massoud Daheshia et al.   JOURNAL OF RHEUMATOLOGY

Specific Renal Uptake of Randomly 50%N-Acetylated Low Molecular Weight Chitosan

(2008) Zhi-xiang Yuan et al.   MOLECULAR PHARMACEUTICS

Stem-cell therapy for cardiac disease

(2008) Vincent F. M. Segers et al.   NATURE

Chitooligosaccharides protect cultured hippocampal neurons against glutamate-induced neurotoxicity

(2008) Songlin Zhou et al.   NEUROSCIENCE LETTERS

Chitosan oligosaccharides attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells

(2008) Hong-Tao Liu et al.   PHARMACOLOGICAL RESEARCH

Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis

(2008) Donna M Urquhart et al.   ARTHRITIS RESEARCH & THERAPY

Estrogen-TGFβ cross-talk in bone and other cell types: Role of TIEG, Runx2, and other transcription factors

(2007) J. R. Hawse et al.   JOURNAL OF CELLULAR BIOCHEMISTRY